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zadetkov: 35
1.
  • SARS-CoV-2 viral proteins N... SARS-CoV-2 viral proteins NSP1 and NSP13 inhibit interferon activation through distinct mechanisms
    Vazquez, Christine; Swanson, Sydnie E; Negatu, Seble G ... PloS one, 06/2021, Letnik: 16, Številka: 6
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    Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has caused a devastating global pandemic, infecting over 43 million people and claiming over 1 million lives, with these numbers ...
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2.
  • Comprehensive functional an... Comprehensive functional analysis of Mycobacterium tuberculosis toxin-antitoxin systems: implications for pathogenesis, stress responses, and evolution
    Ramage, Holly R; Connolly, Lynn E; Cox, Jeffery S PLoS genetics, 12/2009, Letnik: 5, Številka: 12
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    Toxin-antitoxin (TA) systems, stress-responsive genetic elements ubiquitous in microbial genomes, are unusually abundant in the major human pathogen Mycobacterium tuberculosis. Why M. tuberculosis ...
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3.
  • A Combined Proteomics/Genom... A Combined Proteomics/Genomics Approach Links Hepatitis C Virus Infection with Nonsense-Mediated mRNA Decay
    Ramage, Holly R.; Kumar, G. Renuka; Verschueren, Erik ... Molecular cell, 01/2015, Letnik: 57, Številka: 2
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    Hepatitis C virus (HCV) is a leading cause of liver disease, but insight into virus-host interactions remains limited. We systematically used affinity purification/mass spectrometry to define the ...
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4.
  • Controllable protein phase ... Controllable protein phase separation and modular recruitment to form responsive membraneless organelles
    Schuster, Benjamin S; Reed, Ellen H; Parthasarathy, Ranganath ... Nature communications, 07/2018, Letnik: 9, Številka: 1
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    Many intrinsically disordered proteins self-assemble into liquid droplets that function as membraneless organelles. Because of their biological importance and ability to colocalize molecules at high ...
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5.
  • Comparative Flavivirus-Host... Comparative Flavivirus-Host Protein Interaction Mapping Reveals Mechanisms of Dengue and Zika Virus Pathogenesis
    Shah, Priya S.; Link, Nichole; Jang, Gwendolyn M. ... Cell, 12/2018, Letnik: 175, Številka: 7
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    Mosquito-borne flaviviruses, including dengue virus (DENV) and Zika virus (ZIKV), are a growing public health concern. Systems-level analysis of how flaviviruses hijack cellular processes through ...
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6.
  • Drug repurposing screens re... Drug repurposing screens reveal cell-type-specific entry pathways and FDA-approved drugs active against SARS-Cov-2
    Dittmar, Mark; Lee, Jae Seung; Whig, Kanupriya ... Cell reports (Cambridge), 04/2021, Letnik: 35, Številka: 1
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    There is an urgent need for antivirals to treat the newly emerged severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). To identify new candidates, we screen a repurposing library of ∼3,000 ...
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7.
  • Diacylglycerol Acyltransfer... Diacylglycerol Acyltransferase-1 Localizes Hepatitis C Virus NS5A Protein to Lipid Droplets and Enhances NS5A Interaction with the Viral Capsid Core
    Camus, Gregory; Herker, Eva; Modi, Ankit A. ... The Journal of biological chemistry, 04/2013, Letnik: 288, Številka: 14
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    The triglyceride-synthesizing enzyme acyl CoA:diacylglycerol acyltransferase 1 (DGAT1) plays a critical role in hepatitis C virus (HCV) infection by recruiting the HCV capsid protein core onto the ...
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8.
  • Pharmacological activation ... Pharmacological activation of STING blocks SARS-CoV-2 infection
    Li, Minghua; Ferretti, Max; Ying, Baoling ... Science immunology, 05/2021, Letnik: 6, Številka: 59
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    Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has caused a global pandemic, resulting millions of infections and deaths with few effective interventions available. Here, we demonstrate ...
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9.
  • Langerhans cells and cDC1s ... Langerhans cells and cDC1s play redundant roles in mRNA-LNP induced protective anti-influenza and anti-SARS-CoV-2 immune responses
    Ndeupen, Sonia; Bouteau, Aurélie; Herbst, Christopher ... PLoS pathogens, 01/2022, Letnik: 18, Številka: 1
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    Nucleoside modified mRNA combined with Acuitas Therapeutics' lipid nanoparticles (LNPs) has been shown to support robust humoral immune responses in many preclinical animal vaccine studies and later ...
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10.
  • Virus-Host Interactions: Fr... Virus-Host Interactions: From Unbiased Genetic Screens to Function
    Ramage, Holly; Cherry, Sara Annual review of virology, 11/2015, Letnik: 2, Številka: 1
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    Deciphering the many interactions that occur between a virus and host cell over the course of infection is paramount to understanding mechanisms of pathogenesis and to the future development of ...
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zadetkov: 35

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