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•Low-cost carbon – adsorbent was prepared from orange peel waste by simple method.•The synthesised orange peel activated carbon surface area was 592.471 m2 g−1.•Adsorption mechanism ...and kinetics studies of highly hazardous chlorophenoxy herbicides from aqueous was studied.•Maximum Langmuir capacity of 574.71 mg g−1 was achieved.
This study presents the orange peel activated carbon (OPAC), derived from biowaste precursor (orange peel) by single step pyrolysis method and its application for the adsorption of chlorophenoxyacetic acid herbicides from the water. The OPAC exhibited the surface area of 592.471 m2 g−1, pore volume and pore diameter of 0.242 cc g−1 and 1.301 nm respectively. The adsorption kinetics and thermodynamic equilibrium modelling for all chlorophenoxyacetic acid herbicides were investigated. The various parametric effects such as pH and temperature were evaluated. A pseudo-second-order kinetic model was well fitted for all the herbicides. The Langmuir isotherm was obeyed for all the herbicides and the maximum Langmuir capacity of 574.71 mg g−1 was achieved. The thermodynamic studies revealed that the adsorption increases with increase in temperature. The results shows that the orange peel derived carbon (OPAC) as effective and efficient adsorbent material for the removal of chlorophenoxyacid herbicides from the water.
This study deals with the removal of nitrate from water by electrocoagulation process using zinc and stainless steel as anode and cathode respectively. The optimizations of various experimental ...operating parameters like effect of electrolyte pH, current density, temperature, and inter-electrode distance on the removal of nitrate were carried out. The effect of co-existing anions such as carbonate, phosphate, silicate and phosphate was studied on the removal efficiency of nitrate. The results showed that the optimum removal efficiency of 69% was achieved. The maximum removal efficiency was achieved at a current density of 0.1Adm−2 and pH of 7.0. First and second-order rate equations were applied to study adsorption kinetics and the adsorption process follows second order kinetics model with good correlation. The Langmuir adsorption isotherm favors monolayer coverage of adsorbed molecules for adsorption nitrate. Thermodynamic parameters, including the Gibbs free energy, enthalpy, and entropy, indicated that the adsorption of nitrate on zinc hydroxide was feasible, spontaneous and endothermic.
•Nitrate was removed efficiently by in situ prepared zinc hydroxide.•Maximum adsorption efficiency was achieved.•Adsorption equilibrium follows pseudo-second-order model.•Equilibrium data were well described by the typical Langmuir adsorption isotherm.•Thermodynamic studies revealed that the adsorption reaction was spontaneous.
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•MCPP was removed efficiently by one-pot electrosynthesised zinc hydroxide.•Adsorption equilibrium follows pseudo-second-order model.•Equilibrium data were well described by the ...typical Langmuir adsorption isotherm.•Thermodynamic studies revealed that the adsorption reaction was spontaneous.
This present research work investigates the adsorption of hazardous 2-(2-methyl-4-chlorophenoxy) propionic acid (MCPP) from water using electrochemically synthesized zinc hydroxide material. In order to compute the conditions of higher adsorption efficiency, the various parameters such as pH, temperature, current density and the concentration of the contaminant, and inter-electrode distance were studied. The obtained results were analysed by modeling studies viz. Langmuir, Freundlich, D-R isotherm, and Temkin isotherms. The Langmuir isotherm confirms that the monolayer adsorption of 2-(2-methyl-4-chlorophenoxy) propionic acid molecule on the surface of zinc hydroxide. The adsorption mechanism was studied by pseudo-first order, second-order, Elovich model Weber and Morris intraparticle diffusion models. The adsorption of MCPP on zinc hydroxide follows the second-order kinetic model. Based on the heat effect of adsorption, the thermodynamic parameter via enthalpy, entropy, and free energy was evaluated. The calculated thermodynamic parameters endorse that the adsorption was endothermic, spontaneous and thermodynamically feasible.
Citrullus colocynthis (Colocynth) has gained a great deal of interest in their applications as indigenous nutraceutical and as a functional food ingredient. The intact colocynth seed protein was ...enzymatically hydrolyzed using proteolytic enzymes (alcalase, bromelain, and chymotrypsin) at different time intervals of 3, 6, and 9 h. The highest degree of hydrolysis (87.82%) was observed in chymotrypsin derived colocynth seed protein hydrolysates (CSPH) for 9 h. The CSPHs was further investigated through in-vitro assay to explore its potential biological activity such as antioxidant, inhibition of enzymatic marker related to diabetes (DPP-IV, α-glucosidase and α-amylase) and hyperlipidaemia (cholesteryl esterase and pancreatic lipase). Chymotrypsin hydrolysate showed the strongest DPPH (65.7 mM TEAC) and ABTS (525.2 mM TEAC) radical scavenging activity after 6 h of hydrolysis. Moreover, chymotrypsin-treated CSPH for 6 h inhibited cholesteryl esterase (IC50 = 13.68 μg/mL) and pancreatic lipase (IC50 = 14.12 μg/mL) significantly when compared to native protein. Whereas, bromelain and alcalase treated hydrolysate for 6 h effectively inhibited α-glucosidase and α-amylase at an inhibitory concentration of IC50 = 13.27 μg/mL and of IC50 = 17 μg/mL. Overall, the findings indicated that protein hydrolysates exhibited superior biological activity than intact colocynth seed proteins isolate (CSPI) and could be a sustainable source of bioactive peptides.
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•The intact colocynth seed protein was enzymatically hydrolyzed.•The highest hydrolysis was observed in chymotrypsin hydrolysate.•Chymotrypsin hydrolysate showed the strongest antioxidant activity.•Bromelain and alcalase hydrolysate showed strongest inhibition of enzymatic marker related to diabetes.•Chymotrypsin hydrolysate showed the highest inhibition of enzymatic marker related to hyperlipidaemia.
A recent genome-wide association study (GWAS) identified association with variants in X-linked CLDN2 and MORC4, and PRSS1-PRSS2 loci with chronic pancreatitis (CP) in North American patients of ...European ancestry. We selected 9 variants from the reported GWAS and replicated the association with CP in Indian patients by genotyping 1807 unrelated Indians of Indo-European ethnicity, including 519 patients with CP and 1288 controls. The etiology of CP was idiopathic in 83.62% and alcoholic in 16.38% of 519 patients. Our study confirmed a significant association of 2 variants in CLDN2 gene (rs4409525-OR 1.71, P = 1.38 x 10-09; rs12008279-OR 1.56, P = 1.53 x 10-04) and 2 variants in MORC4 gene (rs12688220-OR 1.72, P = 9.20 x 10-09; rs6622126-OR 1.75, P = 4.04x10-05) in Indian patients with CP. We also found significant association at PRSS1-PRSS2 locus (OR 0.60; P = 9.92 x 10-06) and SAMD12-TNFRSF11B (OR 0.49, 95% CI 0.31-0.78, P = 0.0027). A variant in the gene MORC4 (rs12688220) showed significant interaction with alcohol (OR for homozygous and heterozygous risk allele -14.62 and 1.51 respectively, P = 0.0068) suggesting gene-environment interaction. A combined analysis of the genes CLDN2 and MORC4 based on an effective risk allele score revealed a higher percentage of individuals homozygous for the risk allele in CP cases with 5.09 fold enhanced risk in individuals with 7 or more effective risk alleles compared with individuals with 3 or less risk alleles (P = 1.88 x 10-14). Genetic variants in CLDN2 and MORC4 genes were associated with CP in Indian patients.
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