Repeated teenage pregnancy is a major burden on the healthcare system worldwide.
We aimed to compare teenagers with their first and third pregnancies and to evaluate the likelihood of neonatal ...complications.
This cross-sectional study was performed on female teenagers (aged
19 yr) with singleton pregnancies. The subjects (n = 298) were screened over 12 months. Ninety-six women were excluded, based on the exclusion criteria. The remaining subjects (n = 202) were divided into two groups: teenagers with first pregnancy (n = 96) and teenagers with third pregnancy (n = 47). The subjects were observed throughout pregnancy and delivery. The final sample size of the first and third pregnancy groups was 96 and 47, respectively.
There was a significant risk of preeclampsia in the first pregnancy group (p = 0.01). Low birth weight, five-min Apgar score
7, and neonatal intensive care unit admission were the most significant neonatal outcomes in the first pregnancy group. In the third pregnancy group, significant predictors of neonatal complications included very young age in the first pregnancy (
15 yr), an inter-pregnancy interval
2 yr, current anemia, and history of obstetric and/or neonatal complications in previous pregnancies.
Based on the results, teenagers with their first pregnancy had comparable obstetric outcomes (except for preeclampsia) as teenagers with their third pregnancy, whereas neonatal complications occurred more frequently in the first pregnancy group. Overall, we can predict high-risk neonates in the third pregnancy, based on the abovementioned parameters.
We present a study on the correlation of the superconducting critical temperature (Tc) and structural morphology with a chemically substituted high-temperature superconductor (HTS) (Bi,Pb)-2212 via ...Powder X-ray Diffraction (PXRD), Scanning Electron Microscopy (SEM), Energy Dispersive X-ray Spectroscopy (EDX), and d c magnetometry. The elements Zn, Y, Ti, and Nd are incorporated within the bismuth cuprate structure at amounts that extend the ranges currently found in literature.
Drawing on theoretical streams of compensatory control theory, regulatory focus theory, and cognitive load theory, this study proposes and validates a model to illustrate the underlying mechanism of ...panic buying behavior in an online context during the COVID-19 pandemic. Building on the scholarly research on compensatory control theory, regulatory focus theory, and cognitive load theory, this study is one of the preliminary attempts to investigate the relationship between consumer's perceived resilience and vulnerability with COVID-19 threat perceptions and panic buying. This paper also provides a novel empirical inquiry into the moderating role of COVID-19 conspiracy beliefs. Using an online survey, a total of 395 usable responses were collected. The data were collected during the lockdown imposed in May-June 2021 in Pakistan after the country was hit with the second wave of the COVID-19 pandemic. Overall findings signaled that resilient consumers perceived a lesser threat of COVID-19 as compared to vulnerable consumers, and consequently, panic buying disposition was more prevalent among the vulnerable consumers. COVID-19 conspiracy beliefs exhibited significant interaction effects. The implications for the e-commerce sector in general and online retailers, mainly, are discussed regarding panic buying and personality type of consumers.
This study reports on the impact of elevated recovery (i.e., 80%, 85%, and 90%) on the fouling and performance of air gap membrane distillation (AGMD) with real seawater and landfill leachate ...wastewater samples using polytetrafluoroethylene (PTFE) polymer membranes. Increasing the feed temperature from 55 °C to 65 °C improved the water flux of seawater and wastewater and shortened the operating time by 42.8% for all recoveries. The average water flux in the 80%, 85%, and 90% recovery experiments at the 65 °C feed temperature was 32%, 37.32%, and 36.7% higher than the case of 55 °C for the same recoveries. The water flux decline was more severe at a higher temperature and recovery. The highest flux decline was observed with a 90% recovery at 65 °C feed temperature, followed by an 85% recovery at 65 °C. Close examination of the foulants layer revealed that seawater formed a cake fouling layer made predominantly of metal oxides. In contrast, the landfill leachate fouling was a combination of pore blocking and cake formation, consisting mainly of carbonous and nitrogenous compounds. Physical cleaning with deionized (DI) water at 55 °C and 65 °C and chemical cleaning with hydrogen peroxide (H2O2) were investigated for their efficiency in removing membrane foulants. Analytical results revealed that seawater fouling caused membrane pore blockage while wastewater fouling formed a porous layer on the membrane surface. The results showed that membrane cleaning with hydrogen peroxide restored >97% of the water flux. Interestingly, the fouling factor in seawater tests was 10%, while it was 16% for the wastewater tests.
Business technology has brought conventional marketing methods to the next level. These emerging integrated technologies has contributed to the growth and understanding of the consumer decision ...making process. Several studies have attempted to evaluate media content, especially on video advertising or TV commercials using various neuroimaging techniques such as the electroencephalography (EEG) device. Currently, the use of neuroscience in Malaysia’s marketing research is very limited due to its limited adoption as an emerging technology in this field. This research uncovers the neuroscientific approach, particularly through the use of an EEG device; examining consumers’ responses in terms of brain wave signals and cognition. A proposed theoretical framework on the factors affecting visual stimulus (movement, color, shape, and light) during the decision-making process by watching video advertising had been customized using two conceptual models of sensory stimulation. Ten respondents participated in the experiment to investigate the spectral changes of alpha brain wave signals detected in the occipital lobe. A 2-channel Arduino-based EEG device from Backyard Brains and Spike Recorder software was used to analyze the EEG signal through Fast Fourier Transform (FFT) method. Results obtained from the investigated population showed that there was statistically significant brain wave activity during the observation of the video advertising which demonstrated the interconnection with short-term memory through visual stimulus. Application of the neuroscience tool helped to explore consumer brain responses towards marketing stimuli with regards to the consumers’ decision-making processes. This study manifests a useful tool for neuromarketing and concludes with a discussion, together with recommendations on the way forward.
Abstract Geochemical equilibrium models are useful tools for predicting metal solubility and speciation prior to appropriate decisions on remediation possibilities. Therefore, for lead (Pb) ...bioremediation purposes from artificial groundwater are critical to predicting its availability and speciation. This study assesses to predict the solubility and speciation of Pb in laboratory-prepared groundwater under the change in pH, and calcium, phosphate, and humic acid effects using thermodynamic calculation (MINTEQ program). In the results, lead availability declined with an increase in pH, calcium, phosphate, and humic acid of AGW. Rendering to the MINTEQ program, lead binds to some cations exit fewer free ions accessible in AGW such as Pb(SO 4 ) 2 , PbCl + , HA1-Pb, FA1-Pb, FA2-Pb, and HA2-Pb. It is suggested that pH in AGW is maintained at low pH intended for the best obtainability of lead and remediation possibilities.
In the last decades, the development of high‐throughput molecular assays has revolutionised cancer diagnostics, paving the way for the concept of personalised cancer medicine. This progress has been ...driven by the introduction of such technologies through biomarker‐driven oncology trials. In this review, strengths and limitations of various state‐of‐the‐art sequencing technologies, including gene panel sequencing (DNA and RNA), whole‐exome/whole‐genome sequencing and whole‐transcriptome sequencing, are explored, focusing on their ability to identify clinically relevant biomarkers with diagnostic, prognostic and/or predictive impact. This includes the need to assess complex biomarkers, for example microsatellite instability, tumour mutation burden and homologous recombination deficiency, to identify patients suitable for specific therapies, including immunotherapy. Furthermore, the crucial role of biomarker analysis and multidisciplinary molecular tumour boards in selecting patients for trial inclusion is discussed in relation to various trial concepts, including drug repurposing. Recognising that today's exploratory techniques will evolve into tomorrow's routine diagnostics and clinical study inclusion assays, the importance of emerging technologies for multimodal diagnostics, such as proteomics and in vivo drug sensitivity testing, is also discussed. In addition, key regulatory aspects and the importance of patient engagement in all phases of a clinical trial are described. Finally, we propose a set of recommendations for consideration when planning a new precision cancer medicine trial.
There is a growing need for systems that efficiently support the work of medical teams at the precision-oncology point of care. Here, we present the implementation of the Molecular Tumor Board Portal ...(MTBP), an academic clinical decision support system developed under the umbrella of Cancer Core Europe that creates a unified legal, scientific and technological platform to share and harness next-generation sequencing data. Automating the interpretation and reporting of sequencing results decrease the need for time-consuming manual procedures that are prone to errors. The adoption of an expert-agreed process to systematically link tumor molecular profiles with clinical actions promotes consistent decision-making and structured data capture across the connected centers. The use of information-rich patient reports with interactive content facilitates collaborative discussion of complex cases during virtual molecular tumor board meetings. Overall, streamlined digital systems like the MTBP are crucial to better address the challenges brought by precision oncology and accelerate the use of emerging biomarkers.
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