Watchful waiting is an acceptable management strategy for advanced‐stage, low tumor burden (LTB) patients with follicular lymphoma (FL). However, the prediction of how long this treatment‐free ...observation period will last remains imperfect. We explored whether total metabolic tumor volume (TMTV) and other positron emission tomography parameters were predictive of time to first treatment (TTFT). We analyzed 97 grade 1–3A advanced‐stage LTB FL patients and found that a high TMTV was associated with other tumor burden features at diagnosis. Patients with a TMTV above our established cutoff of 50 mL had a significantly shorter median duration of observation (2.6 vs. 8.8 years; p = 0.001). At 5 years, 77% of patients with a high TMTV and 46% of patients with a low TMTV required treatment. In the multivariable analysis, a high TMTV was the only independent factor predicting TTFT (hazard ratio = 2.09; p = 0.017). Overall, TMTV is a strong predictor of the duration of observation in LTB FL patients. Upon validation of our cutoff in external series and standardization of the methodology, the TMTV could become an additional factor to consider deferring or initiating treatment in otherwise LTB patients.
Se desarrolló un sistema interacción humano-robot multimodal (gestos y voz) que permite a usuarios enseñarle tareas de clasificación de cubos por color a un robot. La evaluación del sistema fue ...realizada por siete usuarios de forma cuantitativa y cualitativa. En las pruebas cuantitativas se evaluó un total de 63 interacciones verbales, 252 interacciones gestuales, y 63 multimodales. El porcentaje de reconocimiento de las interacciones fue del 98.41% para los comandos de voz, 81.35 % para los gestuales, y 80.95% para las multimodales. Luego del aprendizaje, el robot fue capaz de realizar correctamente la tarea de clasificación de cubos por color en un 100%; siendo capaz de responder exitosamente ante condiciones iniciales (ubicaciones y cantidad de cubos) no enseñadas previamente. La evaluación cualitativa del sistema se realizó para conocer la percepción de los usuarios, arrojando resultados consistentes con los porcentajes de reconocimiento, favoreciendo la interacción verbal sobre la multimodal.
This study was undertaken in order to identify the relationship between gender of children with autism and risk factors before/during pregnancy and childbirth. An analysis of 66 clinical records was ...divided into two groups defined by gender of children diagnosed with autism in Bogotá (Colombia). The data were collected with the Maternal Perinatal Risk Questionnaire and analyzed with Pearson Chi square. The most significant risks associated with gender in the minors were voluntary abortions, maternal difficulties in a previous pregnancy, surgery during pregnancy, conflicting parental relationships, demanding physical and cognitive activity, consumption of drugs in the mother, duration of pregnancy and birth weight. Among men there was as many prenatal factors while among girls had an enrollment over perinatal factors (before and during labor) and psychosocial.
This study was undertaken in order to identify the relationship between gender of children with autism and risk factors before/during pregnancy and childbirth. An analysis of 66 clinical records was ...divided into two groups defined by gender of children diagnosed with autism in Bogotá (Colombia). The data were collected with the Maternal Perinatal Risk Questionnaire and analyzed with Pearson Chi square. The most significant risks associated with gender in the minors were voluntary abortions, maternal difficulties in a previous pregnancy, surgery during pregnancy, conflicting parental relationships, demanding physical and cognitive activity, consumption of drugs in the mother, duration of pregnancy and birth weight. Among men there was as many prenatal factors while among girls had an enrollment over perinatal factors (before and during labor) and psychosocial.
Éste estudio consistió en identificar la relación entre el género de menores con autismo y los factores de riesgo antes/durante su gestación y parto. Se realizó el análisis de 66 historias clínicas divididas en dos grupos definidos por el género de menores diagnosticados con autismo en la ciudad de Bogotá (Colombia). Los datos se recogieron con el Cuestionario Materno de Riesgo Perinatal y se analizaron con Chi cuadrado de Pearson. Los riesgos más significativos asociados al género en los menores fueron los abortos voluntarios, las dificultades maternas en embarazos anteriores, las intervenciones quirúrgicas durante el embarazo, relaciones parentales conflictivas, actividad física y cognitiva exigentes, consumo de medicamentos en la madre, tiempo de duración del embarazo y el peso del neonato. Entre los varones se registró mayor cantidad de factores prenatales mientras que entre las niñas hubo un registro mayor de factores perinatales (antes y durante el parto) y psicosociales.
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