•Anaerobic co-digestion of two-phase olive-mill waste and cattle manure was studied.•Four total solids contents were studied for a 75:25 mixture of both wastes.•Methane yield and organic matter ...removal were lower as total solids content increased.•The best yield was obtained with the lower total solids content (10%).•57,5% volatile solids removal and 82.5 LCH4/kgVS were reached working at 10% TS.
The solids content is a key parameter in the development of anaerobic digestion as it can determine the proper operation and performance of the process. The influence of the total solids content on the mesophilic anaerobic co-digestion of two-phase olive-mill waste (2POMW) and cattle manure (CM) was investigated. Four different total solids (TS) concentrations, in a 75:25 mixture of 2POMW:CM, were studied in batch reactors of 2 L capacity: 10%TS (R10), 15%TS (R15), 20%TS (R20) and 28.6%TS (Reactor non-diluted). The methane yields and the organic matter removal efficiency for the reactor with 10 and 15% TS were significantly higher than in the reactors with a higher solids content (R20 and Rnd). The hydrolytic and acidogenic phases were not adversely affected by the total solid content since the concentration of volatile fatty acids (VFAs) increased as TS percentage increased. However, a clear effect on the methanogenic phase was observed, which led to the accumulation of VFAs in the reactors R15, R20 and Rnd. Experimental results have shown that the best conditions correspond to the reactor containing 10% TS. The volatile solids and VFA removal in reactor R10 were 57.5% and 93.7% respectively. Moreover, the methane yield and the specific methane production were 35.80 LCH4/kgVSadded and 82.51 LCH4/kgVSremoved respectively.
The analysis of the viability of Hydrogen production without CO
2 emissions is one of the most challenging activities that have been initiated for a sustainable energy supply. As one of the tracks to ...fulfil such objective, direct methane cracking has been analysed experimentally to assess the scientific viability and reaction characterization in a broad temperature range, from 875 to 1700
°C. The effect of temperature, sweeping/carrier gas fraction proposed in some concepts, methane flow rate, residence time, and tube material and porosity has been analysed. The aggregation of carbon black particles to the reaction tube is the main technological show-stopper that has been identified.
► CO
2-free Hydrogen production from methane. ► Experimental methane cracking analysis. ► Black carbon plug as drawback for industrial application.
In this letter, we obtain the maximum likelihood estimator of position in the framework of global navigation satellite systems. This theoretical result is the basis of a completely different approach ...to the positioning problem, in contrast to the conventional two-step position estimation, consisting of estimating the synchronization parameters of the in-view satellites and then performing a position estimation with that information. To the authors' knowledge, this is a novel approach that copes with signal fading, and it mitigates multipath and jamming interferences. Besides, the concept of position-based synchronization is introduced, which states that synchronization parameters can be recovered from a user position estimation. We provide computer simulation results showing the robustness of the proposed approach in fading multipath channels. The root mean square error performance of the proposed algorithm is compared to those achieved with state-of-the-art synchronization techniques. A sequential Monte Carlo-based method is used to deal with the multivariate optimization problem resulting from the maximum likelihood solution in an iterative way
Multipath is known to be one of the most dominant sources of accuracy degradation in satellite-based navigation systems. Multipath may cause biased position estimates that could jeopardize ...high-precision applications. This paper considers the problem of tracking the time-variant synchronization parameters of both the line-of-sight signal (LOSS) and its multipath replicas. In particular, the proposed algorithm tracks time-delays, amplitudes, phases and proposes a procedure to extract Doppler shifts from complex amplitudes. However, the interest is focused on LOSS time-delay estimates, since those provide the means to compute user's position. The undertaken Bayesian approach is implemented by a particle filter. The selection of the importance density function, from which particles are generated, is performed using a Gaussian approximation of the posterior function. This selection provides a particle generating function close to the optimal, which yields to an efficient usage of particles. The complex-linear part of the model, i.e., complex amplitudes, is tackled by a Rao-Blackwellization procedure that implements a complex Kalman filter for each generated particle, thus reducing the computational load. Computer simulation results are compared to other Bayesian filtering alternatives (namely, the extended Kalman filter, the unscented Kalman filter and the sequential importance resampling algorithms) and the posterior Cramer-Rao bound.
The aim of this study was to determine the parameters distinguishing top female futsal players from lower level players. Twenty-seven female futsal players participated in the study, composed of ...professional first division (elite; n = 15) players and semi-professional second division players (sub-elite; n = 14). Active and passive straight leg raise tests, isokinetic strength of the knee extensor and flexor muscles at 60° · s(-1) angular velocity, squat and counter movement jumps, 30 m sprint, 30 m agility, repeated sprint ability test and maximum ball speed during shooting were measured. The elite players were more agile and kicked harder than sub-elite players in maximum ball speed during the shooting test (P ≤ 0.05). However, no significant differences between teams were observed in active and passive hamstring flexibility, jumping ability, repeated sprint ability test, 30 m sprint time, H/Q ratio and absolute and relative torque from 60° · s(-1) angular velocity. Based on these findings we conclude that agility and maximum ball speed during shooting may be important determinant factors of Spanish female futsal actions and could distinguish ability at high-level games.
The genital infection caused by Chlamydia trachomatis (CT) is a common sexually transmitted infection (STI) globally. The infection is mainly asymptomatic in women, thus it can produce infertility ...and chronic pelvic pain. In men infection is mainly symptomatic, but can evolve to prostatitis. Clinical practice guidelines for CT urogenital infections do not give any specific recommendation about which antibiotic use as first option OBJECTIVES: To assess the efficacy and safety of antibiotic treatment for CT genital infection in men and non-pregnant women.
The Cochrane Sexually Transmitted Infections' (STI) Information Specialist developed the electronic searches in electronic databases (CENTRAL, MEDLINE, Embase and LILACS), and trials registers. We searched studies published from inception to June 2018.
We included parallel, randomised controlled trials (RCTs) of men, and sexually-active, non-pregnant women with CT infection (urethritis or uterine cervicitis or asymptomatic), diagnosed by cell culture for CT, nucleic acid amplification tests (NAAT) or antigen-based detection methods, who had been treated with any of the antibiotic regimens recommended by any of the updated to 2013 CT Guidelines.
Four review authors screened evidence according to selection criteria and independently extracted data and assessed risk of bias. Two authors developed the 'Summary of findings' tables. We used a fixed-effect meta-analysis model for combining data where it was reasonable to assume that studies were estimating the same underlying treatment effect. We estimated the pooled risk ratio in order to establish the effects of the comparisons. Our primary outcomes were microbiological failure and adverse events, and our secondary outcomes were clinical failure, antimicrobial resistance and reinfection.
We selected 14 studies ( 2715 participants: 2147 (79.08%) men and 568 (20.92%) women). The studies were conducted mainly at STD clinics. Sample sizes ranged from 71 to 606 participants; follow-up was 29.7 days on average.For the comparison: azithromycin single dose versus doxycycline once or twice daily for 7 days, in men treated for CT, the risk of microbiological failure was higher in the azithromycin group (RR 2.45, 95% CI 1.36 to 4.41; participants = 821; studies = 9; moderate-quality evidence), but regarding clinical failure, the results showed that the effect is uncertain (RR 0.94, 95% CI 0.43 to 2,05; I² = 55%; participants = 525; studies = 3; low-quality evidence). Regarding adverse events (AE) in men there could be little or no difference between the antibiotics (RR 0.83, 95% CI 0.67 to 1.02; participants = 1424; studies = 6; low-quality evidence). About women treated for CT, the effect on microbiological failure was uncertain (RR = 1.71, 95% CI 0.48 to 6.16; participants = 338; studies = 5; very low-quality evidence). There were no studies assessing clinical failure or adverse events in women, however, we found that azithromycin probably has fewer adverse events in both genders (RR 0.83, 95% CI 0.71 to 0.98; I² = 0%; participants = 2261; studies = 9; moderate-quality evidence).For the second comparison: doxycycline compared to ofloxacin, for men treated for CT the effect on microbiological failure was uncertain (RR 8.53, 95% CI 0.43 to 167.38, I² not applicable; participants = 80; studies = 2; very low-quality evidence), as also it was on clinical failure (RR 0.85, 95% CI 0.28 to 2.62; participants = 36; studies = 1; very low-quality evidence). The effect of in women on clinical failure was uncertain (RR 0.94, 95% CI 0.39 to 2.25; I² = 39%; participants = 127; studies = 2; very low-quality evidence).Regarding adverse events, the effect in both men and women was uncertain (RR 1.02 95% CI 0.66 to 1.55; participants = 339 studies = 3; very low-quality evidence). The effect on microbiological failure in women and in men and women together, the effect on microbiological failure was not estimable. The most frequently AE reported were not serious and of gastrointestinal origin.No studies assessed antimicrobial resistance or reinfection in either comparison.
In men, regimens with azithromycin are probably less effective than doxycycline for microbiological failure, however, there might be little or no difference for clinical failure. For women, we are uncertain whether azithromycin compared to doxycycline increases the risk of microbiological failure. Azithromycin probably slightly reduces adverse events compared to doxycycline in men and women together but may have little difference in men alone. We are uncertain whether doxycycline compared to ofloxacin reduces microbiological failure in men or women alone, or men and women together, nor if it reduces clinical failure or adverse events in men or women.Based on the fact that women suffer mainly asymptomatic infections, and in order to test the effectiveness and safety of the current recommendations (azithromycin, doxycycline and ofloxacin), for CT infection, especially in low and middle income countries, future RCTs should be designed and conducted to include a large enough sample size of women, and with low risk of bias. It is also important that future RCTs include adherence, CT resistance to antibiotic regimens, and risk of reinfection as outcomes to be measured. In addition, it is important to conduct a network meta-analysis in order to evaluate all those studies that included in one arm only the current antibiotic treatments for CT infection that are recommended by the updated clinical practice guidelines.
The acid and alkaline phosphatase activities of the clam
Scrobicularia plana have been partially characterised in different organs and tissues (digestive gland, gills, foot, siphon and mantle) and ...the ‘in vitro’ effect of heavy metals on both types of enzymatic activity have been analysed. The optimal pH ranged between 4.0 and 5.5 for acid phosphatase activity and 8.5 and 9.5 for alkaline phosphatase activity. The apparent optimum temperature was in the 30–60° range for acid phosphatase activity and in the 30–40°C range for alkaline phosphatase activity. The effect of substrate concentration on enzymatic activities in the tissues showed a good fit to the Michaelis–Menten model. For both types of enzymatic activity, the highest values were found in the digestive gland. The effect of heavy metals was dependent on the tissue analysed. Mercury showed the highest inhibition in the organs/tissues and the parameters
K
m and
V
max were modified when the inhibitor concentration increased, thus indicating a mixed type of inhibition.
Objective: To compare the effectiveness of two topical medications to reduce the pain and size of recurrent minor aphthous ulcers.
Setting: Ten Colombian Dental Faculties’ clinics.
Design: A ...double‐blind randomized multi‐centre clinical study.
Subjects: Ninety‐six patients complaining of at least five acute aphthous ulcers were randomized to two intervention groups. Sample size was calculated using an alpha error of 0.05 and beta of 0.20
Materials and methods: Participants were randomly assigned to receive 5% amlexanox or a 0.05% clobetasol propionate magistral preparation. Observers at the participating institutions were previously trained to standardize clinical diagnosis and data recollection. Ulcer size and pain were measured on treatment days 0, 2 and 5.
Results: No significant differences were found between the two groups studied in any of the studied variables at baseline. Both treatment medications significantly reduced pain magnitude and the index ulcer's size on days 2 and 5 compared with day 0 without adverse reactions (within groups differences). No statistical differences between groups of the study medications were found.
Conclusion: The two treatments applied had similar effectiveness as they both relieved pain and reduced the size of recurrent aphthous ulcers.
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