Delisle-Houde, P, Chiarlitti, NA, Reid, RER, and Andersen, RE. Relationship between physiologic tests, body composition changes, and on-ice playing time in canadian collegiate hockey players. J ...Strength Cond Res 32(5): 1297-1302, 2018-Hockey player's body composition and physical fitness are suggested to influence coaching decisions regarding on-ice playing time. The purpose of this study was to explore the relationship between seasonal body composition changes, off-ice preseason testing, and on-ice metrics. Twenty-one Canadian collegiate hockey players (22.70 ± 1.30 years old, 181.0 ± 5.92 cm, 86.52 ± 6.41 kg) underwent off-ice physical testing at the beginning of their season and had one total body dual energy x-ray absorptiometry scan at the beginning and end of the season. The team's statistician tracked all on-ice metrics. Pearson correlations were used to explore relationships between off-ice tests (long jump, vertical jump, beep test, and Wingate test), change in body composition (body fat percentage, visceral adiposity, and total lean tissue mass), and on-ice performance (average time on ice, average shift length, power play time, penalty kill time, and shot differential). Long jump was correlated with shot differential (r = -0.532, p ≤ 0.05) and average shift length (r = -0.491, p ≤ 0.05) while fatigue index was correlated with average ice time (r = -0.476, p ≤ 0.05). Hockey performance is a complex interaction of player's body compositions and skeletal fitness that interact to affect on-ice playing metrics.
The demands of early parenthood may limit the pursuit of moderate-to-vigorous intensity physical activity (MVPA); thus, understanding the predictors of MVPA among this population could help build ...targeted intervention programs. Objective: The purpose of this study was to examine the correlates of MVPA, in the form of constructs subsumed within the theory of planned behavior (TPB) and multi-process action control (M-PAC) framework, among new parents participating in in a couple-based PA promotion randomized trial across a six-month period in the first year after birth.
In total, 264 participants (132 couples) at the two-month point of parenting their first child were enrolled in the trial through advertisements. MVPA, TPB, and M-PAC constructs were assessed via self-report at baseline, and six-week, three-month, and six-month after baseline time-periods.
Dyadic path modeling of the TPB showed that intention only predicted MVPA for mothers and PBC did not predict MVPA. Most of the sample had intentions to be physically active, although the extent to which intentions predicted subsequent MVPA was dependent on mothers and fathers reported strength of planning, habits, and exercise identity (M-PAC variables). Intention was subsequently predicted by affective attitude and PBC for mothers and fathers.
Interventions targeting affective attitude and perceived behavioral control may assist in improving MVPA intentions of new parents; yet, additional intervention strategies to increase planning, habit, and especially exercise identity seems warranted for many parents to close the gap between intention and PA. The findings highlight the complementary approach of intention formation and intention translation theories among new parents.
•This study was designed to examine correlates of physical activity among first-time new parents.•Intention predicted behavior for mothers but not fathers.•Perceived behavioral control did not predict behavior for mothers or fathers.•Gender did not moderate those who translated their intentions into behavior.•Planning, habit, and exercise identity predicted those who translated their intentions into behavior.
Spinal muscular atrophy (SMA), caused by loss of the SMN1 gene, is a leading cause of early childhood death. Due to the near identical sequences of SMN1 and SMN2, analysis of this region is ...challenging. Population-wide SMA screening to quantify the SMN1 copy number (CN) is recommended by the American College of Medical Genetics and Genomics.
We developed a method that accurately identifies the CN of SMN1 and SMN2 using genome sequencing (GS) data by analyzing read depth and eight informative reference genome differences between SMN1/2.
We characterized SMN1/2 in 12,747 genomes, identified 1568 samples with SMN1 gains or losses and 6615 samples with SMN2 gains or losses, and calculated a pan-ethnic carrier frequency of 2%, consistent with previous studies. Additionally, 99.8% of our SMN1 and 99.7% of SMN2 CN calls agreed with orthogonal methods, with a recall of 100% for SMA and 97.8% for carriers, and a precision of 100% for both SMA and carriers.
This SMN copy-number caller can be used to identify both carrier and affected status of SMA, enabling SMA testing to be offered as a comprehensive test in neonatal care and an accurate carrier screening tool in GS sequencing projects.
Aims There is growing need for the identification of novel non-invasive methodologies for the identification of individuals at risk for adverse cardiovascular (CV) events. We examined whether ...endothelial dysfunction, as detected by non-invasive peripheral arterial tonometry (EndoPAT), can predict late CV events. Methods and results Reactive hyperaemia (RH) was induced following upper arm occlusion of systolic blood pressure in 270 outpatients (54 ± 12 years, 48% female). The natural logarithmic scaled RH index (L_RHI) was calculated from the ratio between the digital pulse volume during RH and at baseline. The patients were followed for CV adverse events (AE: cardiac death, myocardial infarction, revascularization or cardiac hospitalization) during a 7-year follow-up (inter-quartile range = 4.4–8). Cox models were used to estimate the association of EndoPAT results with AE adjusted for age. During the follow-up, AE occurred in 86 patients (31%). Seven-year AE rate was 48% in patients with L_RHI < 0.4 vs. 28% in those with L_RHI ≥ 0.4 (P = 0.03). Additional univariate predictors of AE were advancing age (P = 0.02) and prior coronary bypass surgery (P = 0.01). The traditional Framingham risk score was not higher in patients with AE. Multivariate analysis identified L_RHI < 0.4 as an independent predictor of AE (P = 0.03). Conclusion A low RH signal detected by EndoPAT, consistent with endothelial dysfunction, was associated with higher AE rate during follow-up. L_RHI was an independent predictor of AE. Non-invasive assessment of peripheral vascular function may be useful for the identification of patients at risk for cardiac AEs.
We present the size evolution of passively evolving galaxies at z ~ 2 identified in Wide-Field Camera 3 imaging from the Early Release Science program. Our sample was constructed using an analog to ...the passive BzK galaxy selection criterion, which isolates galaxies with little or no ongoing star formation at z > ~ 1.5. We identify 30 galaxies in ~40 arcmin super(2) to H < 25 mag. By fitting the 10-band Hubble Space Telescope photometry from 0.22 mu m < ~ lambda sub(obs) < ~ 1.6 mu m with stellar population synthesis models, we simultaneously determine photometric redshift, stellar mass, and a bevy of other population parameters. Based on the six galaxies with published spectroscopic redshifts, we estimate a typical redshift uncertainty of ~0.033(1 + z). We determine effective radii from Sersic profile fits to the H-band image using an empirical point-spread function. By supplementing our data with published samples, we propose a mass-dependent size evolution model for passively evolving galaxies, where the most massive galaxies (Mlow * ~ 10 super(11) M) undergo the strongest evolution from z ~ 2 to the present. Parameterizing the size evolution as (1 + z) super(- alpha ), we find a tentative scaling of alpha approx = (- 0.6 + or - 0.7) + (0.9 + or - 0.4)log(Mlow */10 super(9) M sub(middot in circle)), where the relatively large uncertainties reflect the poor sampling in stellar mass due to the low numbers of high-redshift systems. We discuss the implications of this result for the redshift evolution of the Mlow *-R sub(e) relation for red galaxies.
To understand coastal dispersal dynamics of Atlantic cod (Gadus morhua), we examined spatiotemporal egg and larval abundance patterns in coastal Newfoundland. In recent decades, Smith Sound, Trinity ...Bay has supported the largest known overwintering spawning aggregation of Atlantic cod in the region. We estimated spawning and dispersal characteristics for the Smith Sound-Trinity Bay system by fitting ichthyoplankton abundance data to environmentally-driven, simplified box models. Results show protracted spawning, with sharply increased egg production in early July, and limited dispersal from the Sound. The model for the entire spawning season indicates egg export from Smith Sound is 13%•day(-1) with a net mortality of 27%•day(-1). Eggs and larvae are consistently found in western Trinity Bay with little advection from the system. These patterns mirror particle tracking models that suggest residence times of 10-20 days, and circulation models indicating local gyres in Trinity Bay that act in concert with upwelling dynamics to retain eggs and larvae. Our results are among the first quantitative dispersal estimates from Smith Sound, linking this spawning stock to the adjacent coastal waters. These results illustrate the biophysical interplay regulating dispersal and connectivity originating from inshore spawning of coastal northwest Atlantic.
Domestication is rife with episodes of interbreeding between cultured and wild populations, potentially challenging adaptive variation in the wild. In Atlantic salmon,
, the number of domesticated ...individuals far exceeds wild individuals, and escape events occur regularly, yet evidence of the magnitude and geographic scale of interbreeding resulting from individual escape events is lacking. We screened juvenile Atlantic salmon using 95 single nucleotide polymorphisms following a single, large aquaculture escape in the Northwest Atlantic and report the landscape-scale detection of hybrid and feral salmon (27.1%, 17/18 rivers). Hybrids were reproductively viable, and observed at higher frequency in smaller wild populations. Repeated annual sampling of this cohort revealed decreases in the presence of hybrid and feral offspring over time. These results link previous observations of escaped salmon in rivers with reports of population genetic change, and demonstrate the potential negative consequences of escapes from net-pen aquaculture on wild populations.
•A classic twin study approach to modelling variation in lipid mediators including oxylipins, endocannabinoids, bile acids and steroids.•Heritable lipid mediators included 12-HETE, 12-HEPE, 14-HDoHE ...and DHEA.•12-LOX derived lipid mediators are highly heritable.•Environment contributes to a large proportion of variation for the majority of profiled lipid mediators.
Lipid bioactivity is a result of direct action and the action of lipid mediators including oxylipins, endocannabinoids, bile acids and steroids. Understanding the factors contributing to biological variation in lipid mediators may inform future approaches to understand and treat complex metabolic diseases. This research aims to determine the contribution of genetic and environmental influences on lipid mediators involved in the regulation of inflammation and energy metabolism. This study recruited 138 monozygotic (MZ) and dizygotic (DZ) twins aged 18–65 years and measured serum oxylipins, endocannabinoids, bile acids and steroids using liquid chromatography mass-spectrometry (LC-MS). In this classic twin design, the similarities and differences between MZ and DZ twins are modelled to estimate the contribution of genetic and environmental influences to variation in lipid mediators. Heritable lipid mediators included the 12-lipoxygenase products 12-hydroxyeicosatetraenoic acid 0.70 (95% CI: 0.12,0.82), 12-hydroxyeicosatetraenoic acid 0.73 (95% CI: 0.30,0.83) and 14‑hydroxy-docosahexaenoic acid 0.51 (95% CI: 0.07,0.71), along with the endocannabinoid docosahexaenoy-lethanolamide 0.52 (95% CI: 0.15,0.72). For others such as 13-hydroxyoctadecatrienoic acid and lithocholic acid the contribution of environment to variation was stronger. With increased understanding of lipid mediator functions in health, it is important to understand the factors contributing to their variance. This study provides a comprehensive analysis of lipid mediators and extends pre-existing knowledge of the genetic and environmental influences on the human lipidome.
Supernova (SN) H0pe was discovered as a new transient in
James Webb
Space Telescope (JWST) NIRCam images of the galaxy cluster
PLCK G165.7+67.0
taken as part of the Prime Extragalactic Areas for ...Reionization and Lensing Science (PEARLS) JWST GTO program (ID 1176) on 2023 March 30. The transient is a compact source associated with a background galaxy that is stretched and triply imaged by the strong gravitational lensing of the cluster. This paper reports spectra in the 950–1370 nm observer frame of two of the galaxy images obtained with Large Binocular Telescope (LBT) Utility Camera in the Infrared (LUCI) in long-slit mode two weeks after the JWST observations. The individual and average spectra show the O
II
λλ
3727,3730 doublet and the Balmer and 4000 Å breaks at redshift
z
= 1.783 ± 0.002. The code investigating galaxy emission (CIGALE) best-fit model of the spectral energy distribution indicates that the host galaxy of SN H0pe is massive (
M
star
≃ 6 × 10
10
M
⊙
after correcting for a magnification factor
μ
∼ 7) with a predominantly intermediate-age (∼2 Gyr) stellar population, moderate extinction, and a magnification-corrected star formation rate ≃13
M
⊙
yr
−1
, consistent with being below the main sequence of star formation. These properties suggest that H0pe might be a type Ia SN. Additional observations of SN H0pe and its host recently carried out with JWST (JWST-DD-4446; PI: B. Frye) will be able to both determine the SN classification and confirm its association with the galaxy analyzed in this work.
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