To determine the value of the results of various audiological and vestibulometric studies for the differential diagnosis of non-inflammatory perilymphatic fistulas of the labyrinth windows (PFOLW).
...The retrospective and prospective analysis of the informative value of the results of audiological and vestibulometric studies was carried out in 124 people with different combinations of cochleovestibular complaints, who had different pathology of the inner and middle ear, with different terms of the disease - from several days to 30 years. To assess the informativeness of the applied testing, the following operational characteristics were determined: general sensitivity (Se), specificity (Sp) and the prognostic value of a positive result (PPV=positive predictive value). A pair-by-pair comparison of the prognostic value of a positive result of vestibulometric and audiometric tests was performed using the Pearson criterion χ2 and the exact Fisher criterion.
It is shown that none of the tests used has 100% reliability, but the consistent application of some of them can successfully improve the diagnosis of idiopathic PFOL. When comparing the results of a number of tests, such as the Fukuda walking test and / or the Babinsky-Weil walking test, audiometric tests with head clone and hyperventilation, the test of fluid injection into the external auditory canal and the test of J. Frasser & L. Flood, it was found that the average prognostic value of a positive result was 87.3%, which is statistically significantly higher than the average result (47.9%) for other samples.
Correlations of the results of simple vestibulometric and audiometric tests allow us to recommend them to improve the diagnosis of idiopathic perilymphatic fistulas of the labyrinth windows. The possibilities of modern electrophysiological audiological research methods are subject to further study.
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An azido-derivative of a fluorescein bifluorophore was obtained and used for the synthesis of “molecular beacon”-type oligonucleotide fluorogenic probes for RT-PCR. Eight probe variants were ...synthesized based on an optimized sequence: with one or two quencher residues at the 3'-end, with a single or bifluorophore fluorescein label attached to 5'-end using modifying phosphoramidites (short linker) or “click reaction” (long linker). Comparison of probes in RT-PCR showed that probes with a doubled quencher (single fluorescein on a short linker) and doubled dye on a short linker (single dye) are somewhat superior in sensitivity to a standard probe (single quencher, single dye on a short linker) by the value of ΔC
t
= 1–2.
The SPASCHARM experiment is aimed at a systematic study of the nucleon spin structure and the spin dependence of the strong interaction of antimatter and matter with matter at energies up to 45 GeV. ...As part of the first stage of the experiment, the study of the spin properties of hadrons will take place in a beam of negatively charged hadrons on existing beamline 14 at the operating SPASCHARM setup at the U70 facility. At the second stage, the production of polarized beams of protons and antiprotons is envisaged in beamline 24A of the U-70 accelerator facility. A polarized antiproton beam will certainly become a unique beam in the world. It is planned to measure single-spin asymmetries in dozens of reactions, both on hydrogen and on various nuclei. At the SPASCHARM facility, it is also possible to measure the transverse polarization of hyperons and elements of the spin density matrix of vector mesons. The spin structure of the nucleon will be investigated in the study of quarkonium production to determine the contribution of gluons to the proton spin. The presence of two types of polarized beams and eight types of nonpolarized beams (π
±
,
K
±
,
p
,
,
d
,
C
), in combination with a polarized target, expands the range of studies of polarization phenomena and enhances the uniqueness of the project.
A complex optimization criterion that takes into account the integral quadratic error and the stability margin of a robust digital control system for the rectification column used for the ...butylene-divinyl fraction is proposed. The influence of the weight coefficient, taking into account the ratio of the performance and stability indicators, on the dynamic characteristics of the system is investigated. High system performance and system stability indices over a sufficiently broad range of variation of the parameters of the rectification column are achieved through the use of the proposed optimization criterion and a stability estimation algorithm in the synthesis of a robust digital control system.
The paper analyzes the methods of temperature measurements of cooling the high-temperature bodies in liquids. Experimental studies on cylindrical samples with different embedding of thermocouples ...have been carried out in three liquids. It is shown that even in the case of cooling in saturated liquids, external thermocouples, whose electrodes play the role of cooling fins, distort the measured temperatures significantly. Using external thermocouples, it is impossible to record correctly the rate of hot body cooling in liquid and the temperature of transition of cooling to an intensive regime. Using only a central thermocouple is permissible at low Biot numbers. However, even in this case, with intensive cooling, the difference between the temperatures of the center and the surface can reach several tens of degrees. With a decrease in the thermal conductivity of a sample and an increase in its linear dimensions, the temperature gradient increases (especially at intense cooling), and the correct physical interpretation of the process becomes impossible.
New experimental data on heat transfer in pool film boiling of subcooled ethanol-water mixtures at spherical surfaces are considered. The water solutions with ethanol mass fraction from 10 to 91% and ...temperature of liquid 50°C were examined. All the experiments were conducted under atmospheric pressure, using the stainless steel sphere of 39 mm in diameter as a cooled body. The sphere was heated up to 450-750°C, depending on ethanol concentration, and immersed into the experimental vessel with subcooled mixture. As it is expected, boiling heat transfer intensifies with ethanol concentration decrease, and duration of cooling decreases. It means that stable film boiling duration decreases, and earlier transition to intensive heat transfer regime occurs.
In the context of globalization, Russian systems of education and science have become more open to the contacts with foreign partners. After the period of USSR’s isolation, in 1990s, Russian ...scientists and teachers began actively develop international partnership with foreign universities and research centers, receive grants, participate in conferences abroad, and publish in international journals. Russian graduates and postgraduates became active participants of education migration. In several years, from an ‘iron-curtain’ country Russia turned into a country that offers various forms of academic mobility for scientists, teaching staff and students. The stimulating factor for the international relations’ development was Russia’s accession to the Bologna declaration. In this research, using statistical, analytical, comparative legal, and sociological methods we clarify the term “academic mobility” in its conceptual understanding and suggest a classification of academic mobility’s types. The article describes the trends of the main forms of Russian academic mobility. Moreover, we outline ways to improve Russian national legislation for stimulating academic mobility in the interests of developing the national science and education systems. The article proposes a broad interpretation of the academic mobility’s definition as a mindset and readiness for movement (potential), as well as the actual territorial movement (academic migration) in order to receive education, advanced training, and scientific and educational activities for both students and teaching staff. The academic mobility’s types and forms can be classified in accordance with its geographical (territorial) aspect, activity, duration. Based on the classification, the article summarizes information in the context of two types of international academic mobility: incoming (entry) foreign citizens in Russia and outgoing (exit) Russian citizens from Russia. We have revealed that to a greater extent, the Russian migration legislation covers the academic mobility’s issue more than the legislation on higher education and science. In addition, the migration legislation of international academic mobility is interested more in attracting foreign students and teachers to the country, than in regulating Russian students’ and academic staf f’s mobility abroad. We have highlighted the factors impeding the realization of the Russian academic mobility’s potential and give recommendations for their elimination. The study’s results can be used in economic sociology, sociology of education, migration policy towards students.
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