Background: Replacement of missing tooth plays an important role in patient’s comfort and self-esteem.
Aims and Objectives: The aims of this study were to investigate the most commonly used ...impression materials and techniques practiced for crowns and bridgework by prosthodontists and general dental practitioners compared to the theoretical methods suggested in the literature and to determine the clinical factors that might influence the decision-making process for the selection of impression materials and techniques.
Materials and Methods: Pre-tested and pre-validated structured and closed-ended anonymous questionnaire was shared with general dental practitioners and prosthodontists.
Results: Most of the prosthodontists use diagnostic impression compared to general dental practitioners (P<0.01). Full-arch tray was used by general dental practitioners significantly more frequently compared to prosthodontists (P<0.01) for single anterior, single posterior, anterior, and posterior bridge preparations. Alginate hydrocolloid was used by general dental practitioners significantly more than prosthodontists (P<0.05); however, addition silicone and condensation silicone were used by prosthodontists significantly more than general dental practitioners (P<0.05). For the impression technique followed in case of using elastomeric impression materials, the prosthodontists used the two-step putty reline technique with spacer more commonly, while general dental practitioners used the multiple mix technique (P<0.01). For the use of provisional restoration for single tooth crowns and for all the bridges, prosthodontists used provisional restoration in significantly higher proportion as compared to general dental practitioners (P<0.01).
Conclusion: According to our study compared to general dental practitioners, practices of the prosthodontists regarding use of fixed partial denture is more in line with the current global trend.
Introduction: Classroom lecture absenteeism is a challenging issue among medical educators. The benefit of attending lecture classes on academic performance has already been documented. Very few ...studies have explored the attitude of undergraduate medical students towards classroom lecture absenteeism and its association with the students’ academic performance. Aim: To explore undergraduate medical students’ attitude towards classroom lecture absenteeism, its association (if any) with academic performance (measured by total marks obtained in semester marks) and also to evaluate the attitude of the students towards attending classroom lectures on pre and paraclinical subjects. Materials and Methods: This anonymous structured questionnaire based observational study was conducted in the Departments of Biochemistry and Pharmacology in the month of September 2021, of a tertiary care government medical college. Phase 1 (n=98) (batch 2021-22) and phase 2 (n=97) (batch 2020-2021) MBBS students of the government medical college were included. Descriptive statistics, Chi-square test and one-way Analysis of Variance (ANOVA) tests were used to analyse the data. The p≤0.05 was considered as statistically significant. Results: Out of 195 students, (male: female ratio being 2:1) 94.87% stayed at hostel. Most of them (51.28%) agreed to attend the classroom lectures for pre and paraclinical subjects for getting attendance. It significantly affected the academic performance of the students (p=0.005). A 61.02% students wanted the lecture classes for pre and paraclinical subjects to be optional. Again 76.92% of them thought attending lecture classes have positive impact on their academic performance. The choice of opinion significantly (p<0.001) affected their academic performances. A 56.41% of the students agreed to skip lecture classes 2-3 times per week and cited the most common reason being “not liking the teaching of a particular teacher.” The choice of the students significantly affected the academic performance (p<0.001). A 67.69% of them opined that by reducing the duration of the class, classroom lecture classes on pre and paraclinical subjects can be improved, and there was significant association between the choice and the academic performance of the students (p<0.001). Conclusion: Although majority of the students understood the positive impact of lecture classes on academic performances and they do not want the lecture classes to become optional, they wanted certain modifications like making the traditional didactic lecture classes more interactive, exam oriented, and concept based. Also some of their attitudes (if not all) affected their academic performances significantly.
Background: Autosomal dominant polycystic kidney disease (ADPKD) is a frequent cause of end-stage renal disease. Despite improvements in blood pressure and conventional treatment, there seems not any ...significant impact on the need for renal replacement therapy in these cases. Inhibition of cyclic adenosine monophosphate pathway by tolvaptan was efficient in preclinical/animal studies and in clinical studies involving ADPKD patients; tolvaptan (vasopressin V2 receptor antagonist) has been recently released in the market to delay disease progression.
Aims and Objectives: The aim of this study is to evaluate the role of tolvaptan in reduction of total kidney volume (TKV), total renal cyst volume, and decrease of progression of renal impairment and restoration of kidney function.
Materials and Methods: We have screened 60 cases, of whom 54 were assigned to either tolvaptan group (36) or placebo (18). Overall 36 cases completed the trial (24 from tolvaptan group and 12 cases from placebo group). Estimated GFR (glomerular filtration rate) calculated and stages were noted. TKV and total cyst volume measured by ultrasonography at days 0, 30, 90, and 180 along with other vitals. The total number of patients enrolled was randomly divided into two broad groups by concealed envelop technique: Intervention group (with tolvaptan) and placebo or control group. The intervention group was given tolvaptan along with standard conventional management for ADPKD as per relevant stages. The placebo group was given placebo tablets with same size and color (multivitamin tablet) along with standard conventional management for ADPKD as per relevant stages. The periodic estimation of cyst volume, kidney volume, serum creatinine level, and estimated glomerular filtration rate recorded and analyzed with ANOVA method with confidence interval 95%.
Results: Analysis of the data showed fewer ADPKD-related events per cases of follow-up with tolvaptan than with placebo. These results were confirmed by the analysis of the 1st time and after 6 months of study. Our data suggest that increase of TKV and total cyst volume was less in tolvaptan group as compared to placebo group. Overall, treatment effect on the growth of TKV was 0.219% per month with a P<0.0001.
Conclusions: The administration of tolvaptan for 6 months was associated with slowed kidney growth and functional decline and with a reduced frequency of ADPKD-related complications among patients with a relatively preserved GFR.
Arsenic, though a poor mutagen, is an accepted environmental carcinogen. Perturbation of DNA methylation pattern leading to aberrant gene expression has been hypothesized as the mechanism for arsenic ...induced carcinogenesis. We had earlier demonstrated the hypermethylation of promoter region of p53 and p16 genes in persons exposed to different doses of arsenic. Till now no genomic hot spot has been identified which is frequently hypermethylated or hypomethylated in persons chronically exposed to environmental arsenic. In the present work, we have identified one hypermethylated sequence by methyl-sensitive arbitrarily primed polymerase chain reaction in the peripheral blood leukocyte DNA of chronically arsenic exposed persons with and without arsenic induced skin cancer. The sequence is from GMDS gene responsible for fucose metabolism. Southern hybridization of the sequence to the amplification products of methyl sensitive restriction enzyme digested genome of persons exposed to different doses of arsenic indicated that methylation increased in a dose dependent manner.
Use of 169Yb as a calibration standard Bhattacharya, Sarmishtha; Bandyopadhyay, Dipa; Saha, Sankar Kumar ...
Nuclear instruments & methods in physics research. Section A, Accelerators, spectrometers, detectors and associated equipment,
08/1996, Letnik:
378, Številka:
3
Journal Article
Recenzirano
The energies and intensities of the gamma and X-rays in the decay of 169Yb (32 d) have been measured with a low energy photon spectrometer (LEPS) and a high purity germanium (HPGe) detector. This ...source is recommended for use as a standard for low-energy efficiency calibration of such detectors. It is also proposed to use this source as a standard for conversion electrons, as the multipolarities and mixing ratios are well known for most strong transitions.
The high spin states in the {sup 139}Ce nucleus have been studied by in-beam {gamma}-spectroscopic techniques using the reaction {sup 130}Te({sup 12}C,3n){sup 139}Ce at E{sub beam}=65 MeV. A gamma ...detector array, consisting of five Compton-suppressed Clover detectors was used for coincidence measurements. 15 new levels have been proposed and 28 new {gamma} transitions have been assigned to {sup 139}Ce on the basis of {gamma}{gamma} coincidence data. The level scheme of {sup 139}Ce has been extended above the known 70 ns (19/2){sup -} isomer up to {approx}6.1 MeV in excitation energy and (35/2)({Dirac_h}/2{pi}) in spin. The spin-parity assignments for most of the newly proposed levels have been made using the deduced Directional Correlation from Oriented states of nuclei (DCO ratio) and the Polarization Directional Correlation from Oriented states (PDCO ratio) for the de-exciting transitions. The observed level structure has been compared with a large basis shell model calculation and also with the predictions from cranked Nilsson-Strutinsky (CNS) calculations. A general consistency has been observed between these two different theoretical approaches.
Excited states of {sup 137}Ce, populated in the {sup 130}Te({sup 12}C,5n) reaction at a beam energy of 65 MeV, have been investigated by {gamma}{gamma} coincidence spectroscopy using a modest Clover ...Ge array. Unique spin-parity assignments have been made for most of the levels at high spin and excitation energy by using DCO ratios and polarization information. The known level scheme of {sup 137}Ce has been considerably revised on the basis of the new information. A sequence of M1 transitions, developed on the 5379.1-keV (33/2)({Dirac_h}/2{pi}) level has been suggested to be a positive-parity band through unambiguous assignment of multipolarity of 1124.1- and 836.1-keV {gamma} rays. Another positive-parity bandlike structure has been seen, starting at the 2928.4-keV (19/2){sup +} level. Total Routhian surface calculations have been done to predict underlying multi-quasiparticle configurations for the observed bands.
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