Radioisotope power systems utilising americium-241 as a source of heat have been under development in Europe as part of a European Space Agency funded programme since 2009. The aim is to develop all ...of the building blocks that would enable Europe to launch and operate deep space and planetary missions in environments where use of solar power or alternative power generation technologies is challenging. Although some technical and policy work activity predate the ESA programme, the maturity of the technology has now reached a level that it can be incorporated in mission studies and roadmaps targeting the period from the mid 2020s onwards. This paper describes the state of the art in European radioisotope thermoelectric generators and radioisotope heater units. This paper includes: the evolution of the technical programme in detail; descriptions of the design; evolution of RTG and RHU devices from laboratory prototypes to more advanced fully functional systems; and experimental data obtained to date. This paper also outlines the technical challenges and multidisciplinary skills required to develop what is a world leading, original, significant and transformative technology solution for planetary science and exploration missions from the mid 2020s onwards.
Background
A prototype anthropomorphic head and neck phantom has been designed to simulate the adult head and neck anatomy including some internal organs and tissues of interest, such as thyroid ...gland and sentinel lymph nodes (SLNs). The design of the head and neck phantom includes an inner jig holding the simulated SLNs and thyroid gland. The thyroid gland structure was manufactured using three-dimensional (3D) printing taking into consideration the morphology and shape of a healthy adult thyroid gland.
Result
The head and neck phantom was employed to simulate a situation where there are four SLNs distributed at two different vertical levels and at two depths within the neck. Contrast to noise ratio (CNR) calculations were performed for the detected SLNs at an 80 mm distance between both pinhole collimators (0.5 and 1.0 mm diameters) and the surface of the head and neck phantom with a 100 s acquisition time. The recorded CNR values for the simulated SLNs are higher when the hybrid gamma camera (HGC) was fitted with the 1.0 mm diameter pinhole collimator. For instance, the recorded CNR values for the superficially simulated SLN (15 mm depth) containing 0.1 MBq of
99m
Tc using 0.5 and 1.0 mm diameter pinhole collimators are 6.48 and 16.42, respectively (~87% difference).
Gamma and hybrid optical images were acquired using the HGC for the simulated thyroid gland. The count profiles through the middle of the simulated thyroid gland images provided by both pinhole collimators were obtained. The HGC could clearly differentiate the individual peaks of both thyroid lobes in the gamma image produced by the 0.5-mm pinhole collimator. In contrast, the recorded count profile for the acquired image using the 1.0-mm-diameter pinhole collimator showed broader peaks for both lobes, reflecting the degradation of the spatial resolution with increasing the diameter of the pinhole collimator.
Conclusions
This anthropomorphic head and neck phantom provides a valuable tool for assessing the imaging ability of gamma cameras used for imaging the head and neck region. The standardisation of test phantoms for SFOV gamma systems will provide an opportunity to collect data across various medical centres. The phantom described is cost effective, reproducible, flexible and anatomically representative.
The Mid-InfraRed Instrument (MIRI) on the James Webb Space Telescope (JWST) provides measurements over the wavelength range 5 to 28.5 μm. MIRI has, within a single "package," four key scientific ...functions: photometric imaging, coronagraphy, single-source low-spectral resolving power (R ∼ 100) spectroscopy, and medium-resolving power (R ∼ 1500 to 3500) integral field spectroscopy. An associated cooler system maintains MIRI at its operating temperature of < 6.7 K. This paper describes the driving principles behind the design of MIRI, the primary design parameters, and their realization in terms of the "as-built" instrument. It also describes the test program that led to delivery of the tested and calibrated Flight Model to NASA in 2012, and the confirmation after delivery of the key interface requirements.
The Life Marker Chip (LMC) is one of the instruments being developed for possible flight on the 2018 ExoMars mission. The instrument uses solvents to extract organic compounds from samples of martian ...regolith and to transfer the extracts to dedicated detectors based around the use of antibodies. The scientific aims of the instrument are to detect organics in the form of biomarkers that might be associated with extinct life, extant life or abiotic sources of organics. The instrument relies on a novel surfactant-based solvent system and bespoke, commercial and research-developed antibodies against a number of distinct biomarkers or molecular types. The LMC comprises of a number of subsystems designed to accept up to four discrete samples of martian regolith or crushed rock, implement the solvent extraction, perform microfluidic-based multiplexed antibody-assays for biomarkers and other targets, optically detect the fluorescent output of the assays, control the internal instrument pressure and temperature, in addition to the associated instrument control electronics and software. The principle of operation, the design and the instrument development status as of December 2011 are reported here. The instrument principle can be extended to other configurations and missions as needed.
► Life Marker Chip is an immunoassay based life detection instrument. ► LMC is part of the payload for the 2018 ExoMars mission. ► Current status of the Life Marker Chip Instrument for ExoMars.
The Life Marker Chip (LMC) is one of the instruments being developed for possible flight on the 2018 ExoMars mission. The instrument uses solvents to extract organic compounds from samples of martian ...regolith and to transfer the extracts to dedicated detectors based around the use of antibodies. The scientific aims of the instrument are to detect organics in the form of biomarkers that might be associated with extinct life, extant life or abiotic sources of organics. The instrument relies on a novel surfactant-based solvent system and bespoke, commercial and research-developed antibodies against a number of distinct biomarkers or molecular types. The LMC comprises of a number of subsystems designed to accept up to four discrete samples of martian regolith or crushed rock, implement the solvent extraction, perform microfluidic-based multiplexed antibody-assays for biomarkers and other targets, optically detect the fluorescent output of the assays, control the internal instrument pressure and temperature, in addition to the associated instrument control electronics and software. The principle of operation, the design and the instrument development status as of December 2011 are reported here. The instrument principle can be extended to other configurations and missions as needed.
The Mid-InfraRed Instrument (MIRI) on the James Webb Space Telescope (JWST) provides measurements over the wavelength range 5 to 28.5 microns. MIRI has, within a single 'package', four key scientific ...functions: photometric imaging, coronagraphy, single-source low-spectral resolving power (R ~ 100) spectroscopy, and medium-resolving power (R ~ 1500 to 3500) integral field spectroscopy. An associated cooler system maintains MIRI at its operating temperature of < 6.7 K. This paper describes the driving principles behind the design of MIRI, the primary design parameters, and their realization in terms of the 'as-built' instrument. It also describes the test program that led to delivery of the tested and calibrated Flight Model to NASA in 2012, and the confirmation after delivery of the key interface requirements.