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zadetkov: 96
1.
  • Sizing and phenotyping of c... Sizing and phenotyping of cellular vesicles using Nanoparticle Tracking Analysis
    Dragovic, Rebecca A., MSc; Gardiner, Christopher, PhD; Brooks, Alexandra S., MD ... Nanomedicine, 12/2011, Letnik: 7, Številka: 6
    Journal Article
    Recenzirano
    Odprti dostop

    Abstract Cellular microvesicles and nanovesicles (exosomes) are involved in many disease processes and have major potential as biomarkers. However, developments in this area are constrained by ...
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2.
  • Latest Advances in Understa... Latest Advances in Understanding Preeclampsia
    Redman, Christopher W; Sargent, Ian L Science (American Association for the Advancement of Science), 06/2005, Letnik: 308, Številka: 5728
    Journal Article
    Recenzirano

    Preeclampsia is a relatively common pregnancy disorder that originates in the placenta and causes variable maternal and fetal problems. In the worst cases, it may threaten the survival of both mother ...
Celotno besedilo
3.
  • Lysosomal dysfunction incre... Lysosomal dysfunction increases exosome-mediated alpha-synuclein release and transmission
    Alvarez-Erviti, Lydia; Seow, Yiqi; Schapira, Anthony H ... Neurobiology of disease, 06/2011, Letnik: 42, Številka: 3
    Journal Article
    Recenzirano
    Odprti dostop

    Abstract Alpha-synuclein aggregation plays a central role in Parkinson's disease pathology. Direct transmission of alpha-synuclein from pathologically affected to healthy unaffected neurons may be ...
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4.
  • Characterisation of syncyti... Characterisation of syncytiotrophoblast vesicles in normal pregnancy and pre-eclampsia: expression of Flt-1 and endoglin
    Tannetta, Dionne S; Dragovic, Rebecca A; Gardiner, Chris ... PloS one, 02/2013, Letnik: 8, Številka: 2
    Journal Article
    Recenzirano
    Odprti dostop

    The placental syncytiotrophoblast releases micro and nanovesicles (STBM), into the maternal circulation in normal pregnancy and in increased amounts in pre-eclampsia (PE), which have proinflammatory ...
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5.
  • Differential expression pro... Differential expression profile of microRNAs in human placentas from preeclamptic pregnancies vs normal pregnancies
    Zhu, Xiao-ming, MD; Han, Tao, MD; Sargent, Ian L., PhD ... American journal of obstetrics and gynecology, 06/2009, Letnik: 200, Številka: 6
    Journal Article
    Recenzirano

    Objective The purpose of this study was to perform a comprehensive analysis of the microRNA expression profile in placentas from preeclamptic pregnancies vs normal placentas. Study Design Placentas ...
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6.
  • Exosome-mediated delivery of siRNA in vitro and in vivo
    El-Andaloussi, Samir; Lee, Yi; Lakhal-Littleton, Samira ... Nature protocols, 12/2012, Letnik: 7, Številka: 12
    Journal Article
    Recenzirano

    The use of small interfering RNAs (siRNAs) to induce gene silencing has opened a new avenue in drug discovery. However, their therapeutic potential is hampered by inadequate tissue-specific delivery. ...
Preverite dostopnost
7.
  • Endoplasmic reticulum stres... Endoplasmic reticulum stress stimulates the release of extracellular vesicles carrying danger-associated molecular pattern (DAMP) molecules
    Collett, Gavin P; Redman, Christopher W; Sargent, Ian L ... Oncotarget, 2018-Jan-23, Letnik: 9, Številka: 6
    Journal Article
    Odprti dostop

    Disturbances in endoplasmic reticulum (ER) function lead to ER stress which, when severe or prolonged, may result in apoptosis. Severe ER stress has been implicated in several pathological conditions ...
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8.
  • Placental Vesicles Carry Active Endothelial Nitric Oxide Synthase and Their Activity is Reduced in Preeclampsia
    Motta-Mejia, Carolina; Kandzija, Neva; Zhang, Wei ... Hypertension (Dallas, Tex. 1979), 08/2017, Letnik: 70, Številka: 2
    Journal Article
    Recenzirano
    Odprti dostop

    Preeclampsia, a multisystem hypertensive disorder of pregnancy, is associated with increased systemic vascular resistance. Placentae from patients with preeclampsia have reduced levels of endothelial ...
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9.
  • Immunology of pre-eclampsia Immunology of pre-eclampsia
    Redman, Christopher W G; Sargent, Ian L American journal of reproductive immunology (1989), 06/2010, Letnik: 63, Številka: 6
    Journal Article
    Recenzirano

    Pre-eclampsia develops in stages, only the last being the clinical illness. This is generated by a non-specific, systemic (vascular), inflammatory response, secondary to placental oxidative stress ...
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10.
  • Syncytiotrophoblast Extrace... Syncytiotrophoblast Extracellular Vesicles from Pre-Eclampsia Placentas Differentially Affect Platelet Function
    Tannetta, Dionne S; Hunt, Kathryn; Jones, Chris I ... PloS one, 11/2015, Letnik: 10, Številka: 11
    Journal Article
    Recenzirano
    Odprti dostop

    Pre-eclampsia (PE) complicates around 3% of all pregnancies and is one of the most common causes of maternal mortality worldwide. The pathophysiology of PE remains unclear however its underlying ...
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zadetkov: 96

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