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zadetkov: 4
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  • Endothelium‐mediated regula... Endothelium‐mediated regulation of platelet activation: Involvement of multiple protein kinases
    Provenzale, Isabella; Solari, Fiorella A.; Schönichen, Claudia ... The FASEB journal, 29 February 2024, 2024-Feb-29, 2024-02-29, 20240229, Letnik: 38, Številka: 4
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    The endothelial regulation of platelet activity is incompletely understood. Here we describe novel approaches to find molecular pathways implicated on the platelet–endothelium interaction. Using ...
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  • RNA interference screens di... RNA interference screens discover proteases as synthetic lethal partners of PI3K inhibition in breast cancer cells
    Hölzen, Lena; Mitschke, Jan; Schönichen, Claudia ... Theranostics, 01/2022, Letnik: 12, Številka: 9
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    PI3K/mTOR signaling is frequently upregulated in breast cancer making inhibitors of this pathway highly promising anticancer drugs. However, PI3K-inhibitors have a low therapeutic index. Therefore, ...
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  • Blood Coagulation and Beyon... Blood Coagulation and Beyond: Position Paper from the Fourth Maastricht Consensus Conference on Thrombosis
    Akbulut, Asim Cengiz; Arisz, Ryanne A; Baaten, Constance C F M J ... Thrombosis and haemostasis, 08/2023, Letnik: 123, Številka: 8
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    The Fourth Maastricht Consensus Conference on Thrombosis included the following themes. Theme 1: The "coagulome" as a critical driver of cardiovascular disease. Blood coagulation proteins also play ...
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