Fast radio bursts are astronomical radio flashes of unknown physical nature with durations of milliseconds. Their dispersive arrival times suggest an extragalactic origin and imply radio luminosities ...that are orders of magnitude larger than those of all known short-duration radio transients. So far all fast radio bursts have been detected with large single-dish telescopes with arcminute localizations, and attempts to identify their counterparts (source or host galaxy) have relied on the contemporaneous variability of field sources or the presence of peculiar field stars or galaxies. These attempts have not resulted in an unambiguous association with a host or multi-wavelength counterpart. Here we report the subarcsecond localization of the fast radio burst FRB 121102, the only known repeating burst source, using high-time-resolution radio interferometric observations that directly image the bursts. Our precise localization reveals that FRB 121102 originates within 100 milliarcseconds of a faint 180-microJansky persistent radio source with a continuum spectrum that is consistent with non-thermal emission, and a faint (twenty-fifth magnitude) optical counterpart. The flux density of the persistent radio source varies by around ten per cent on day timescales, and very long baseline radio interferometry yields an angular size of less than 1.7 milliarcseconds. Our observations are inconsistent with the fast radio burst having a Galactic origin or its source being located within a prominent star-forming galaxy. Instead, the source appears to be co-located with a low-luminosity active galactic nucleus or a previously unknown type of extragalactic source. Localization and identification of a host or counterpart has been essential to understanding the origins and physics of other kinds of transient events, including gamma-ray bursts and tidal disruption events. However, if other fast radio bursts have similarly faint radio and optical counterparts, our findings imply that direct subarcsecond localizations may be the only way to provide reliable associations.
To investigate the controls on continental rifting in the western branch of the East Africa Rift System, we conduct shear velocity imaging of the crust and uppermost mantle beneath the weakly ...extended Malawi Rift and the Rungwe Volcanic Province (RVP). We use local‐scale measurements of Rayleigh wave phase velocities between 9‐ and 100‐s periods combined with constraints on basin architecture and crustal thickness to invert for shear velocity from the surface to ~135 km. Our resulting 3‐D model reveals a localized low‐velocity anomaly associated with the RVP extending from the crust and through the upper mantle, which can be explained with modestly elevated temperatures. Away from the RVP, velocities within mantle flanking the rift are fast (>4.6 ± 0.1 km/s), suggesting depleted lithospheric mantle to depths of ~100 and >135 km to the west and east of the rift, respectively. The upper mantle beneath the rift axis is characterized by thinned lithosphere with slower velocities than the surrounding plateau, suggestive of thermal and/or chemical modification by the rifting process. Slowest velocities are mildly asymmetric about the rift axis, with the lowest velocities observed beneath the rift and adjacent footwall escarpments. The underlying asthenosphere is only moderately slow (~4.25 ± 0.1 km/s), including beneath the RVP, precluding the presence of significant volumes of partial melt. The positions of localized lithospheric modification and basin‐bounding border faults correlate with the location of Proterozoic mobile belts, suggesting that these sutures provide lithospheric‐scale weakening mechanisms necessary for localizing strain and allowing extension to occur in the Malawi Rift.
Key Points
Moderately reduced shear wave velocities (ΔVs ~ 4–10%) relative to surrounding lithosphere are observed in the upper mantle beneath the Malawi Rift and the Rungwe Volcanic Province
Localized low velocities beneath Rungwe can be explained by modestly elevated temperatures and preclude significant melt
Shear wave velocity structure beneath the Malawi Rift suggests lithospheric modification localized along ancient sutures enabled initiation of rifting
The precise localization of the repeating fast radio burst (FRB 121102) has provided the first unambiguous association (chance coincidence probability p 3 × 10−4) of an FRB with an optical and ...persistent radio counterpart. We report on optical imaging and spectroscopy of the counterpart and find that it is an extended (0 6-0 8) object displaying prominent Balmer and O iii emission lines. Based on the spectrum and emission line ratios, we classify the counterpart as a low-metallicity, star-forming, mr′ = 25.1 AB mag dwarf galaxy at a redshift of z = 0.19273(8), corresponding to a luminosity distance of 972 Mpc. From the angular size, the redshift, and luminosity, we estimate the host galaxy to have a diameter 4 kpc and a stellar mass of M* ∼ (4-7) × 107 M , assuming a mass-to-light ratio between 2 to 3 M L −1. Based on the H flux, we estimate the star formation rate of the host to be 0.4 M yr−1 and a substantial host dispersion measure (DM) depth 324 pc cm−3. The net DM contribution of the host galaxy to FRB 121102 is likely to be lower than this value depending on geometrical factors. We show that the persistent radio source at FRB 121102's location reported by Marcote et al. is offset from the galaxy's center of light by ∼200 mas and the host galaxy does not show optical signatures for AGN activity. If FRB 121102 is typical of the wider FRB population and if future interferometric localizations preferentially find them in dwarf galaxies with low metallicities and prominent emission lines, they would share such a preference with long gamma-ray bursts and superluminous supernovae.
We undertook coordinated campaigns with the Green Bank, Effelsberg, and Arecibo radio telescopes during Chandra X-ray Observatory and XMM-Newton observations of the repeating fast radio burst FRB ...121102 to search for simultaneous radio and X-ray bursts. We find 12 radio bursts from FRB 121102 during 70 ks total of X-ray observations. We detect no X-ray photons at the times of radio bursts from FRB 121102 and further detect no X-ray bursts above the measured background at any time. We place a 5 upper limit of 3 × 10−11 erg cm−2 on the 0.5-10 keV fluence for X-ray bursts at the time of radio bursts for durations ms, which corresponds to a burst energy of 4 × 1045 erg at the measured distance of FRB 121102. We also place limits on the 0.5-10 keV fluence of 5 × 10−10 and 1 × 10−9 erg cm−2 for bursts emitted at any time during the XMM-Newton and Chandra observations, respectively, assuming a typical X-ray burst duration of 5 ms. We analyze data from the Fermi Gamma-ray Space Telescope Gamma-ray Burst Monitor and place a 5 upper limit on the 10-100 keV fluence of 4 × 10−9 erg cm−2 (5 × 1047 erg at the distance of FRB 121102) for gamma-ray bursts at the time of radio bursts. We also present a deep search for a persistent X-ray source using all of the X-ray observations taken to date and place a 5 upper limit on the 0.5-10 keV flux of 4 × 10−15 erg s−1 cm−2 (3 × 1041 erg s−1 at the distance of FRB 121102). We discuss these non-detections in the context of the host environment of FRB 121102 and of possible sources of fast radio bursts in general.
We present results of the coordinated observing campaign that made the first subarcsecond localization of a fast radio burst, FRB 121102. During this campaign, we made the first simultaneous ...detection of an FRB burst using multiple telescopes: the VLA at 3 GHz and the Arecibo Observatory at 1.4 GHz. Of the nine bursts detected by the Very Large Array at 3 GHz, four had simultaneous observing coverage at other observatories at frequencies from 70 MHz to 15 GHz. The one multi-observatory detection and three non-detections of bursts seen at 3 GHz confirm earlier results showing that burst spectra are not well modeled by a power law. We find that burst spectra are characterized by a ∼500 MHz envelope and apparent radio energy as high as 1040 erg. We measure significant changes in the apparent dispersion between bursts that can be attributed to frequency-dependent profiles or some other intrinsic burst structure that adds a systematic error to the estimate of dispersion measure by up to 1%. We use FRB 121102 as a prototype of the FRB class to estimate a volumetric birth rate of FRB sources Mpc−3 yr−1, where Nr is the number of bursts per source over its lifetime. This rate is broadly consistent with models of FRBs from young pulsars or magnetars born in superluminous supernovae or long gamma-ray bursts if the typical FRB repeats on the order of thousands of times during its lifetime.
The millisecond-duration radio flashes known as fast radio bursts (FRBs) represent an enigmatic astrophysical phenomenon. Recently, the sub-arcsecond localization (∼100 mas precision) of FRB 121102 ...using the Very Large Array has led to its unambiguous association with persistent radio and optical counterparts, and to the identification of its host galaxy. However, an even more precise localization is needed in order to probe the direct physical relationship between the millisecond bursts themselves and the associated persistent emission. Here, we report very-long-baseline radio interferometric observations using the European VLBI Network and the 305 m Arecibo telescope, which simultaneously detect both the bursts and the persistent radio emission at milliarcsecond angular scales and show that they are co-located to within a projected linear separation of 40 pc ( 12 mas angular separation, at 95% confidence). We detect consistent angular broadening of the bursts and persistent radio source (∼2-4 mas at 1.7 GHz), which are both similar to the expected Milky Way scattering contribution. The persistent radio source has a projected size constrained to be 0.7 pc ( 0.2 mas angular extent at 5.0 GHz) and a lower limit for the brightness temperature of T b 5 × 10 7 K . Together, these observations provide strong evidence for a direct physical link between FRB 121102 and the compact persistent radio source. We argue that a burst source associated with a low-luminosity active galactic nucleus or a young neutron star energizing a supernova remnant are the two scenarios for FRB 121102 that best match the observed data.
Polygenic inheritance plays a central role in Parkinson disease (PD). A priority in elucidating PD etiology lies in defining the biological basis of genetic risk. Unraveling how risk leads to ...disruption will yield disease-modifying therapeutic targets that may be effective. Here, we utilized a high-throughput and hypothesis-free approach to determine biological processes underlying PD using the largest currently available cohorts of genetic and gene expression data from International Parkinson’s Disease Genetics Consortium (IPDGC) and the Accelerating Medicines Partnership-Parkinson’s disease initiative (AMP-PD), among other sources. We applied large-scale gene-set specific polygenic risk score (PRS) analyses to assess the role of common variation on PD risk focusing on publicly annotated gene sets representative of curated pathways. We nominated specific molecular sub-processes underlying protein misfolding and aggregation, post-translational protein modification, immune response, membrane and intracellular trafficking, lipid and vitamin metabolism, synaptic transmission, endosomal–lysosomal dysfunction, chromatin remodeling and apoptosis mediated by caspases among the main contributors to PD etiology. We assessed the impact of rare variation on PD risk in an independent cohort of whole-genome sequencing data and found evidence for a burden of rare damaging alleles in a range of processes, including neuronal transmission-related pathways and immune response. We explored enrichment linked to expression cell specificity patterns using single-cell gene expression data and demonstrated a significant risk pattern for dopaminergic neurons, serotonergic neurons, hypothalamic GABAergic neurons, and neural progenitors. Subsequently, we created a novel way of building de novo pathways by constructing a network expression community map using transcriptomic data derived from the blood of PD patients, which revealed functional enrichment in inflammatory signaling pathways, cell death machinery related processes, and dysregulation of mitochondrial homeostasis. Our analyses highlight several specific promising pathways and genes for functional prioritization and provide a cellular context in which such work should be done.
We present optical, near-infrared, and mid-infrared imaging of the host galaxy of FRB 121102 with the Gemini North telescope, the Hubble Space Telescope, and the Spitzer Space Telescope. The FRB ...121102 host galaxy is resolved, revealing a bright star-forming region located in the outskirts of the irregular, low-metallicity dwarf galaxy. The star-forming region has a half-light radius of 0.68 kpc ( ), encompassing the projected location of the compact ( pc), persistent radio source that is associated with FRB 121102. The half-light diameter of the dwarf galaxy is 5-7 kpc, and broadband spectral energy distribution fitting indicates that it has a total stellar mass of . The properties of the host galaxy of FRB 121102 are comparable to those of extreme emission line galaxies, also known as hosts to some hydrogen-poor superluminous supernovae and long-duration γ-ray bursts. The projected location of FRB 121102 within the star-forming region supports the proposed connection of FRBs with newly born neutron stars or magnetars.
The coherent elastic scattering of neutrinos off nuclei has eluded detection for four decades, even though its predicted cross section is by far the largest of all low-energy neutrino couplings. This ...mode of interaction offers new opportunities to study neutrino properties and leads to a miniaturization of detector size, with potential technological applications. We observed this process at a 6.7σ̃ confidence level, using a low-background, 14.6-kilogram CsINa scintillator exposed to the neutrino emissions from the Spallation Neutron Source at Oak Ridge National Laboratory. Characteristic signatures in energy and time, predicted by the standard model for this process, were observed in high signal-to-background conditions. Improved constraints on nonstandard neutrino interactions with quarks are derived from this initial data set.
Titan is the only satellite in our Solar System with a dense atmosphere. The surface pressure is 1.5 bar (ref. 1) and, similar to the Earth, N2 is the main component of the atmosphere. Methane is the ...second most important component, but it is photodissociated on a timescale of 107 years (ref. 3). This short timescale has led to the suggestion that Titan may possess a surface or subsurface reservoir of hydrocarbons to replenish the atmosphere. Here we report near-infrared images of Titan obtained on 26 October 2004 by the Cassini spacecraft. The images show that a widespread methane ocean does not exist; subtle albedo variations instead suggest topographical variations, as would be expected for a more solid (perhaps icy) surface. We also find a circular structure ∼30 km in diameter that does not resemble any features seen on other icy satellites. We propose that the structure is a dome formed by upwelling icy plumes that release methane into Titan's atmosphere.