A high-energy, wavelength-tunable, all-polarization-maintaining Er-doped ultrashort fiber laser was demonstrated using a polyimide film dispersed with single-wall carbon nanotubes. A variable output ...coupler and wavelength filter were used in the cavity configuration, and high-power operation was demonstrated. The maximum average power was 12.6 mW and pulse energy was 585 pJ for stable single-pulse operation with an output coupling ratio as high as 98.3%. Wide wavelength-tunable operation at 1532-1562 nm was also demonstrated by controlling the wavelength filter. The RF amplitude noise characteristics were examined in terms of their dependence on output coupling ratio and oscillation wavelength.
An ultralow-repetition-rate, all-polarization-maintaining (PM), Er-doped, ultrashort-pulse fiber laser was demonstrated using a single-wall-carbon-nanotube polyimide film. Using a ring cavity ...configuration, output pulses with pulse energy of 0.7-2.6 nJ were obtained at an ultralow repetition rate of 943-154 kHz for a fiber length of 0.1-1.3 km. A novel θ (theta) cavity configuration was proposed, which enabled us to reduce the required fiber length by half. A repetition rate of 132 kHz was achieved using this configuration with 909 m of PM fiber.
To present the relationship between TARDBP gene mutation and clinicopathologic findings of a Japanese pedigree affected by familial amyotrophic lateral sclerosis (FALS).
The clinical, genetic, and ...neuropathologic characteristics of 4 members of a Japanese pedigree affected by FALS were examined.
All the patients showed motor neuron signs, and 2 of them also had parkinsonism. We identified A315E TARDBP mutation in one patient per clinical disease type and found loss of anterior horn cells, Bunina bodies, and phosphorylated TDP-43-positive neuronal and glial cytoplasmic inclusions in both the patients. However, the patient with only motor neuron signs had degeneration of the posterior column and spinocerebellar tracts as well as neuronal loss of the Clarke column, and the patient with both motor neuron signs and parkinsonism had severe nigral degeneration without Lewy pathology.
The clinical and neuropathologic phenotypes of FALS may differ even with the same mutation of TARDBP, encoding TDP-43. Isolated TDP-43 pathology can produce ALS-plus syndrome.
Response to commentary by Kageura et al Sawano, T; Takita, M; Senoo, Y ...
QJM : An International Journal of Medicine,
01/2022, Letnik:
114, Številka:
12
Journal Article
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