Kako bismo utvrdili postiže li se povećanjem dodatka organskoga selena u hranu odbite prasadi povećanje rasta, djeluje li to na povećanje imunog odgovora i utječe li veća doza na zdravlje i ...homeostazu, u istraživanje su uključene dvije skupine odbite prasadi (N=40), križanaca (LW x SL) x Pietrein, istog omjera spolova, u dobi od 28 do 70 dana. Kontrolna skupina (C) prasadi hranjena je uz dodatak 0,4 mg/kg organskog selena (Sel-Plex®, Alltech Inc.®), a pokusna skupina (E) prasadi hranjena je smjesama uz dodatak 0,7 mg/kg organskog selena (Sel-Plex, Alltech Inc.). Praćeni su
tjelesna masa, prosječni prirasti, hematološki pokazatelji 21. dana pokusa, biokemijski pokazatelji (glukoza, urea, kreatinin, trigliceridi, ukupni kolesterol, HDL i LDL kolesterol, ukupni proteini, željezo, kalcij, aktivnost enzima AST, ALT, GGT, LDH, CK i C reaktivni protein) 21. i 41. dana pokusa. Skupina odbite prasadi hranjena uz dodatak povišene razine organskog selena postigla je veću tjelesnu masu, značajno veći (P<0,05) ukupni prirast tijekom 41 dana pokusa, uz bolju konverziju hrane. Nije bilo utjecaja na aktivnost enzima AST, ALT, GGT, LDH, CK, odnos LDH/AST i CRP. Nisu utvrđene značajne razlike hematoloških i biokemijskih pokazatelja. Nakon 21 dana pokusa utvrđena je niža koncentracija ukupnog i LDL kolesterola u pokusnih životinja, ali bez statističke značajnosti.
Povišena sedimentacija eritrocita (SE) je skoro stalni nalaz u bolesnika s kroničnim bubrežnim zatajenjem, kako u onih liječenih ponavljanim hemodijalizama, tako i u onih liječenih peritonejskom ...dijalizom. Zbog toga je upitna korist njenog određivanja. Etiologija nije jsna, a ni razlike između dvije skupine bolesnika. U ovom radu uspoređene su prosječne vrijednosti SE, određene modificiranom Westergrenovom metodom, bolesnika liječenih hemodijalizom i peritonejskom dijalizom, s ciljem da se razlika dovede u uzročnu vezu sa eventualnim razlikama niza analiziranih laboratorijskih parametara. Bolesnici liječeni hemodijalizom (n = 49) imali su značajno nižu SE (55,51±32,21 mm/3,6 ks) od bolesnika liječenih peritonejskom dijalizom (n = 24 (91,75±31,94 mm/3,6 ks) (t = 4,54 p < 0,01). No, razlika se ne može u potpunosti objasniti nađenim razlikama prosječnih vrijednosti hematokrita, leukocita, srednjeg korpuskularnog volumena eritrocita, fibrinogena, Creaktivnog proteina, pojedinih elektroforezom dobivenih komponenti proteina plazme, kolesterola i triglicerida. U zaključku autori ističu da je povišena SE skoro stalni nalaz u bolesnika liječenih dijalizom i da je izrazito viša u bolesnika liječenih peritonejskom dijalizom. Njeno određivanje u ovih bolesnika je od male koristi.
Analiza metaboličkog profila mliječnih koza provedena je na jednom
ekološkom gospodarstvu od 30 koza, francuske alpina pasmine, u ranoj laktaciji. Sadržaj glukoze (3,17 mmol/l) u krvnoj plazmi koza ...ukazuje na zadovoljavajuću opskrbu životinja energijom, a sadržaj ureje (2,76 mmol/l) na nešto slabiju opskrbu bjelančevinama. Koncentracije mineralnih tvari (Na, K, Cl, Mg i Ca) i anion gap u krvnoj plazmi koza ukazuju na dobru opskrbljenost koza mineralima. Vrijednosti acidobaznog statusa krvi (pH, parcijalni tlak kisika- pO2, parcijalni tlak ugljičnog dioksida- pCO2 i sadržaj bikarbonata-HCO3 -)
kreću se u granicama referentnih vrijednosti za koze.
Koncentracije nekih hematoloških parametara (hemoglobin i hema-tokrit) u krvnoj plazmi koza kretale su se u granicama referentnih vrijednosti za koze. Rezultati ovih istraživanja pokazuju da bi obroke mliječnih koza u ranoj laktaciji u ekološkoj proizvodnji trebalo poja-čati bjelančevinama te da se metabolički profil može uzeti kao vrlo dobar pokazatelj hranidbenog statusa i zdravstvenog stanja koza.
Istraživanje je provedeno na 28 janjadi podijeljene u dvije skupine (C -kontrolna i E - pokusna). Istraživanje je započelo 15. dan starosti janjadi i trajalo do 77. dana starosti. Janjadi u skupini E ...dodan je u hranu probiotic BioPlus 2B. Janjad u skupini E imala je veću tjelesnu masu (za 1.90%), veći dnevni prirast (za 2.50/%), povećani dnevni unos i bolju konverziju hrane u usporedbi sa skupinom C ali razlike između skupina nisu bile statistički znaćajne. Janjad skupine E imala je u serumu krvi statistički manju koncentraciju ureje (5.51 : 7.97 mmol/1) i triglicerida (O.22 : 0.35 mmol/l) u usporedbi sa skupinom C. Nisu primijećene značajne razlike između janjadi skupina E i C u razini glukoze u krvi (2.67 : 2.45 mmol/l), kolesterola (1.25 : 1.08 mmol/1), ukupnih bjelančevina (66.08 : 63.70 g/l), kreatinina 52.01 : 48.0 umol/l) i albumina (27.68 : 28.35 g/l) Rezultati pokazuju umjeren porast metaboličke aktivnosti kod janjadi u skupini E.
Aim To investigate the association of nephrolithiasis and
solute carrier family 2, facilitated glucose transporter,
member 9 (SLC2A9), also known as glucose transporter
type 9, Glut9.
Methods A total ...of 145 participants were recruited in the
period April-October 2008 from the Department of Mineral
Research of the Medical School Osijek, Osijek, Croatia; 58
(40%) had confirmed nephrolithiasis and 87 (60%) were asymptomatic.
Four single nucleotide polymorphisms (SNP)
from the SLC2A9 gene were genotyped in both groups
(rs733175, rs6449213, rs1014290, and rs737267).
Results There was a weak but significant association of all
4 SNPs and nephrolithiasis (P = 0.029 for rs733175; P = 0.006
for rs6449213; P = 0.020 for rs1014290, and P = 0.011 for
rs737267). Logistic regression in an age- and sex-adjusted
model suggested that genotype C/T for rs6449213 had
odds ratio for nephrolithiasis of 2.89 (95% confidence interval
1.13-7.40). This SNP explained a total of 4.4% of nephrolithiasis
variance.
Conclusion Development of nephrolithiasis may be associated
with SLC2A9 gene. Further studies are needed to
clarify the role of SLC2A9 gene as a link between uric acid
and nephrolithiasis.
Metabolic parameters were determined in fasting blood serum, fasting first morning urine, and 24-hour urine of male patients with recurrent calcium oxalate stones (N=26, age 39.1±6.2 years) as well ...as in male healthy controls (N=18, age 35.0±7.1 years), recruited from the eastern part of Croatia. The 24-hour urinary calcium excretion was significantly higher (p<0.01) for patients (5.6±2.5 mmol) than for controls (3.7±1.9 mmol), but potassium excretion was higher (p<0.01) for controls (74.5±33.8 mmol) than for patients (49.2±15.7 mmol). The mean ionic activity product of calcium and oxalate ions, IAP(CaOx), calculated from the fasting first morning urine parameters, was 25% higher for patients than for controls, but the difference was not statistically significant (p>0.05). Very strong correlation (r=0.97) was obtained between IAP(CaOx) values and calculated Ogawa indices that were recommended for estimating the potential risk for calcium oxalate stone formation.
Cancer morbidity and mortality are on a steady increase in Croatia. Technologic possibilities for appropriate managementare available for four cancer sites, i.e. cancer of the breast, cervix uteri, ...colorectum and prostate, and includecancer prevention and early detection in individuals yet free from manifest signs of the disease. The magnitude of the problem, the experience acquired to date, health care personnel available, and additional resources required to launch a systematic program of early detection of the disease are presented. The program should be initially launched in a county with greatest experience in early detection of cancer, where health care service is ready to immediately start its implementation. The role of family physician, gynecologic service at primary health care level, and polyclinic-consultation hospital service in program implementation is described. The following three possible options for early detection of cancer are analyzed and proposed: minimal program (early detection every 3 years), medium program (the same individuals examined every 2 years), and optimal program proposed by the American Cancer Society and other national and international organizations.
This paper examines the impact of perceived consistency in marketing communications on customer–brand relationship outcomes. The perception of consistent message and image through different marketing ...communication tools is one of the basic principles of the integrated marketing communications (IMC) approach. Although literature suggests that IMC might have an influence on customer–brand relationship outcomes, empirical evidence that supports this assumption is still weak and inconclusive. Three main brand relationship outcomes are established for the purpose of the study, i.e. trust, commitment, and loyalty. The relationships between perceived communication consistency and brand outcomes are examined in a hospitality context on a sample of 452 respondents who had to evaluate fast-food brands. Structural Equation Modelling was employed as the main technique for data analysis using Partial Least Squares (PLS). Results reveal that communication consistency has a strong direct impact on brand trust and brand loyalty. Although its influence on affective brand commitment is found to be positive, it is not statistically significant. The interrelationship between three brand relationship outcomes is also corroborated. The study contributes to our understanding of the role of IMC in the relationship marketing paradigm and provides deeper insights into the impact of communication consistency on different relationship outcomes with fast-food brands.
