In 42 children aged 2 months to 16 years who had foreign bodies and blind wounds in the maxillofacial region, the authors examined the causes of damages which had caused penetration of foreign bodies ...into this anatomical part. Clinical examinations showed that there was a relationship between age, the nature of damage, and the variety of foreign bodies in children in contrast to adults. A working scheme was proposed, which reflects the nature of foreign bodies and blind maxillofacial wounds depending on the physiological periods of childhood.
Clinical follow-up of children aged 2 to 14 with tumors and tumor-like formations permitted diagnose secondary deformations of maxillary bones in 44. Symptomatology of these deformations had signs ...which distinguished intraosteally growing tumors from extraosseous ones localized in soft tissues adjacent to jaw bones. Good results were attained with the use of protective labial and buccal plates which not only shielded bone formations from tumor pressure before surgery but created a support for compressive dressing during sclerosing therapy of vascular tumors in children. Reconstructive and orthodontic measures, implantation of prostheses are necessary in the active period of growth and formation of maxillofacial and dental system after organ-destroying surgery for tumors and tumors-like formations in order to not only repair the anatomical shape but more so to optimize the conditions for normal functioning of the growing and forming maxillofacial and dental system of a child.
Focal demineralization of bone tissue with local dosed vacuum (exposure of up to 20 sec) and 2% lithium chloride electrophoresis (8 sessions daily, 10 min exposure) was tried in 40 white rats (21 ...reference ones and 19 experimental). The maximal reduction of mineral content was achieved on days 3-7 after the end of the course and made up 76.2 +/- 15.0% (p less than 0.01) and 80.6 +/- 12.5% (p less than 0.001), respectively, as against the reference animals. Mineral content at the site of demineralization gradually normalized by day 21. This transient reduction of mineral content of bone tissue may be used in orthodontic treatment of dentition abnormalities.
Electrophoresis in polyacrylamide gel of the reference influenza A/Victoria/35/72 (H3N2) virus and its persisting variants (PV) showed that the PV isolated on the 158th day from the moment of ...persistence modelling (PV158) had mutation in the gene of hemagglutinin (HA). This mutation is manifested by incomplete HA synthesis at 40 degrees C and increase of mobility of the light HA subunit (HA2). Analysis of nucleotide sequence of the greater part of HA gene of PV158 virus revealed 5 nucleotide substitutions four of which were significant. Three substitutions were found in Hal: 219 (Ser---Phe), 220 (Arg---Gly), 226 (Leu---Gln) and one in HA2: 156 (Thr---Asn). The importance of these mutations in the determination of the PV phenotype is discussed.
Properties of ts mutants isolated from systems of persistent influenza infection formed in MDCK cell culture by A/Victoria/35/72 virus were studied. The ts mutants isolated at later intervals of ...persistent infection (158 days) were characterized by thermolability of hemagglutinin and neuraminidase, changes in the EP mobility of HA2 polypeptide, decrease in the molecular weight of this polypeptide, appearance of multiple ts mutations in genes 3, 5, 6, 7, and 8, coding for P2, NP, NA, M, and NS proteins, respectively.
