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zadetkov: 37
1.
  • Myostatin is a direct regul... Myostatin is a direct regulator of osteoclast differentiation and its inhibition reduces inflammatory joint destruction in mice
    Dankbar, Berno; Fennen, Michelle; Brunert, Daniela ... Nature medicine, 09/2015, Letnik: 21, Številka: 9
    Journal Article
    Recenzirano

    Myostatin (also known as growth and differentiation factor 8) is a secreted member of the transforming growth factor-β (TGF-β) family that is mainly expressed in skeletal muscle, which is also its ...
Celotno besedilo
2.
  • Autoinhibitory regulation o... Autoinhibitory regulation of S100A8/S100A9 alarmin activity locally restricts sterile inflammation
    Vogl, Thomas; Stratis, Athanasios; Wixler, Viktor ... The Journal of clinical investigation, 05/2018, Letnik: 128, Številka: 5
    Journal Article
    Recenzirano
    Odprti dostop

    Autoimmune diseases, such as psoriasis and arthritis, show a patchy distribution of inflammation despite systemic dysregulation of adaptive immunity. Thus, additional tissue-derived signals, such as ...
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3.
  • Sclerostin inhibition promotes TNF-dependent inflammatory joint destruction
    Wehmeyer, Corinna; Frank, Svetlana; Beckmann, Denise ... Science translational medicine, 2016-Mar-16, Letnik: 8, Številka: 330
    Journal Article
    Recenzirano

    Sclerostin, an inhibitor of the Wnt/β-catenin pathway, has anti-anabolic effects on bone formation by negatively regulating osteoblast differentiation. Mutations in the human sclerostin gene (SOST) ...
Preverite dostopnost
4.
  • Early structural changes in... Early structural changes in cartilage and bone are required for the attachment and invasion of inflamed synovial tissue during destructive inflammatory arthritis
    Korb-Pap, Adelheid; Stratis, Athanasios; Mühlenberg, Katja ... Annals of the rheumatic diseases, 06/2012, Letnik: 71, Številka: 6
    Journal Article
    Recenzirano
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    To elucidate the mechanisms involved in cartilage damage in an experimental model of rheumatoid arthritis (RA) by specifically addressing the time course of extracellular matrix degradation and the ...
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5.
  • Localized Inflammatory Skin... Localized Inflammatory Skin Disease Following Inducible Ablation of I Kappa B Kinase 2 in Murine Epidermis
    Stratis, Athanasios; Pasparakis, Manolis; Markur, Doreen ... Journal of investigative dermatology, 03/2006, Letnik: 126, Številka: 3
    Journal Article
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    Skin inflammation is a complex process that involves interactions between various cell types residing in different skin compartments. Using mice with conditionally targeted I kappa B kinase 2 (IKK2) ...
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6.
  • Mathematical analysis of de... Mathematical analysis of deterministic and stochastic problems in complex media electromagnetics
    Roach, G. F; Stratis, I. G; Yannacopoulos, A. N 2012., 20120304, 2012, 2012-03-04, Letnik: 42
    eBook

    Electromagnetic complex media are artificial materials that affect the propagation of electromagnetic waves in surprising ways not usually seen in nature. Because of their wide range of important ...
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7.
  • Pathogenic role for skin ma... Pathogenic role for skin macrophages in a mouse model of keratinocyte-induced psoriasis-like skin inflammation
    Stratis, Athanasios; Pasparakis, Manolis; Rupec, Rudolf A ... The Journal of clinical investigation 116, Številka: 8
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    Recenzirano
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    Psoriasis is a common skin disease, the pathogenesis of which has not yet been resolved. In mice, epidermis-specific deletion of inhibitor of NF-kappaB (IkappaB) kinase 2 (IKK2) results in a skin ...
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8.
  • Activated macrophages are e... Activated macrophages are essential in a murine model for T cell-mediated chronic psoriasiform skin inflammation
    Wang, Honglin; Peters, Thorsten; Kess, Daniel ... The Journal of clinical investigation 116, Številka: 8
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    The CD18 hypomorphic (CD18hypo) PL/J mouse model clinically resembling human psoriasis is characterized by reduced expression of the common chain of beta2 integrins (CD11/CD18) to only 2-16% of WT ...
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9.
  • Syndecan-4 Modulates Epithe... Syndecan-4 Modulates Epithelial Gut Barrier Function and Epithelial Regeneration in Experimental Colitis
    Fröhling, Mareike; Tepasse, Phil; Intemann, Johanna ... Inflammatory bowel diseases, 12/2018, Letnik: 24, Številka: 12
    Journal Article
    Recenzirano

    Abstract Background The transmembrane heparan sulfate proteoglycan Syndecan-4 (Sdc4) plays an important role in the regulation of various inflammatory disorders. However, the involvement of Sdc4 in ...
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10.
  • Crosstalk between Keratinoc... Crosstalk between Keratinocytes and Adaptive Immune Cells in an IκBα Protein-Mediated Inflammatory Disease of the Skin
    Rebholz, Bernd; Haase, Ingo; Eckelt, Birgit ... Immunity, 08/2007, Letnik: 27, Številka: 2
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    Inflammatory diseases at epithelial borders develop from aberrant interactions between resident cells of the tissue and invading immunocytes. Here, we unraveled basic functions of epithelial cells ...
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zadetkov: 37

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