With the Large Hadron Collider entering its third year of granting us insight into the highest collision energies to date, one should nevertheless keep in mind the unexplored physics potential of ...lower energies. A prime example here is the NA61/SHINE experiment at the CERN Super Proton Synchrotron. Using its large-acceptance hadronic spectrometer, SHINE aims to accomplish a number of physics goals: measuring spectra of identified hadrons in hadron-nucleus collisions to provide reference for accelerator neutrino experiments and cosmic-ray observatories, investigating particle properties in the large transverse-momentum range for hadron+hadron and hadron+nucleus collisions for studying the nuclear modification factor at SPS energies, and measuring hadronic observables in a particularly interesting region of the phase diagram of strongly-interacting matter to study the onset of deconfinement and search for the critical point of strongly-interacting matter with nucleus-nucleus collisions. This contribution shall summarise results obtained so far by NA61/SHINE, as well as present the current status and plans of its experimental programme.
Ensembl 2021 Howe, Kevin L; Achuthan, Premanand; Allen, James ...
Nucleic acids research,
01/2021, Letnik:
49, Številka:
D1
Journal Article
Recenzirano
Odprti dostop
Abstract
The Ensembl project (https://www.ensembl.org) annotates genomes and disseminates genomic data for vertebrate species. We create detailed and comprehensive annotation of gene structures, ...regulatory elements and variants, and enable comparative genomics by inferring the evolutionary history of genes and genomes. Our integrated genomic data are made available in a variety of ways, including genome browsers, search interfaces, specialist tools such as the Ensembl Variant Effect Predictor, download files and programmatic interfaces. Here, we present recent Ensembl developments including two new website portals. Ensembl Rapid Release (http://rapid.ensembl.org) is designed to provide core tools and services for genomes as soon as possible and has been deployed to support large biodiversity sequencing projects. Our SARS-CoV-2 genome browser (https://covid-19.ensembl.org) integrates our own annotation with publicly available genomic data from numerous sources to facilitate the use of genomics in the international scientific response to the COVID-19 pandemic. We also report on other updates to our annotation resources, tools and services. All Ensembl data and software are freely available without restriction.
Abstract
The Ensembl (https://www.ensembl.org) is a system for generating and distributing genome annotation such as genes, variation, regulation and comparative genomics across the vertebrate ...subphylum and key model organisms. The Ensembl annotation pipeline is capable of integrating experimental and reference data from multiple providers into a single integrated resource. Here, we present 94 newly annotated and re-annotated genomes, bringing the total number of genomes offered by Ensembl to 227. This represents the single largest expansion of the resource since its inception. We also detail our continued efforts to improve human annotation, developments in our epigenome analysis and display, a new tool for imputing causal genes from genome-wide association studies and visualisation of variation within a 3D protein model. Finally, we present information on our new website. Both software and data are made available without restriction via our website, online tools platform and programmatic interfaces (available under an Apache 2.0 license) and data updates made available four times a year.
Abstract
The Ensembl project (https://www.ensembl.org) makes key genomic data sets available to the entire scientific community without restrictions. Ensembl seeks to be a fundamental resource ...driving scientific progress by creating, maintaining and updating reference genome annotation and comparative genomics resources. This year we describe our new and expanded gene, variant and comparative annotation capabilities, which led to a 50% increase in the number of vertebrate genomes we support. We have also doubled the number of available human variants and added regulatory regions for many mouse cell types and developmental stages. Our data sets and tools are available via the Ensembl website as well as a through a RESTful webservice, Perl application programming interface and as data files for download.
Angular correlations of high-
p
T
hadrons can serve as a probe of interactions of partons with the dense medium produced in high-energy heavy-ion collisions but other effects may also be important at ...SPS energies. To study the various contributions, NA49 has performed an energy and system-size scan of two-particle azimuthal correlations in
Pb+
Pb,
Si+
Si and
p+
p collisions at
s
N
N
=
17.3
GeV
, as well as central
Pb+
Pb collisions at 6.3, 7.6, 8.8 and 12.3 GeV. These results were compared to UrQMD simulations.
NA49 results show a flattened away side of
C
2
(
Δ
ϕ
)
in central
Pb+
Pb (
Au+
Au) collisions which depends weakly on collision energy even for low SPS energies. This is at odds with the standard scenario of parton energy loss. On the other hand, the near-side peak amplitude drops visibly with decreasing collision energy, turning into a depletion below
s
N
N
=
8.8
GeV
. UrQMD describes the correlation functions on the away side but disagrees on the near side.
RootJS: Node.js Bindings for ROOT 6 Beffart, Theo; Früh, Maximilian; Haas, Christoph ...
Journal of physics. Conference series,
10/2017, Letnik:
898, Številka:
7
Journal Article
Recenzirano
Odprti dostop
We present rootJS, an interface making it possible to seamlessly integrate ROOT 6 into applications written for Node.js, the JavaScript runtime platform increasingly commonly used to create ...high-performance Web applications. ROOT features can be called both directly from Node.js code and by JIT-compiling C++ macros. All rootJS methods are invoked asynchronously and support callback functions, allowing non-blocking operation of Node.js applications using them. Last but not least, our bindings have been designed to platform-independent and should therefore work on all systems supporting both ROOT 6 and Node.js. Thanks to rootJS it is now possible to create ROOT-aware Web applications taking full advantage of the high performance and extensive capabilities of Node.js. Examples include platforms for the quality assurance of acquired, reconstructed or simulated data, book-keeping and e-log systems, and even Web browser-based data visualisation and analysis.
Identification of electromagnetic fields in the vicinity of high voltage overhead transmission lines requires taking measurements and determining, on their basis, the maximum values of electric ...(Emax) and magnetic (Hmax) field strength, as well as the width of the area with electric field strength exceeding 1 kV/m. Measurements should be carried out in the places, where the distance between phase wires and the ground is smallest, and their results converted to conditions expected at the most disadvantageous parameters of the work of line in terms of their effect on the environment. This requires taking into consideration the maximum voltage of the transmission line, as well as the highest acceptable temperature of wires. In a single-circuit line, convertion of the measured values to expected maximum values of Emax and Hmax is not difficult, although it requires knowledge of cross-profiles in spans, in which measurements were taken. However, recounting the values of magnetic field strength produced by two-circuit lines creates a serious problem. Since in the majority of cases, the measurements in the surrounding of two-circuit lines are carried out at asymmetrical currents in both circuits, converting their results to symmetrical currents of the lines is practically impossible. Therefore, the results of the measurements of magnetic field strength carried out at the asymmetrical current of a two-circuit line cannot provide the basis for assessing the possibility of exceeding the allowable value of magnetic field intensity determined in the binding regulations. Such an assessment can only be done on the basis of the results of relevant calculations.
Over the recent years some countries have introduced norms, regulations or recommendations limiting the value of few A/m permissible levels of the 50 Hz magnetic field (MF) in the environment. This ...results from the studies indicating a number of biological effects on living organisms exposed to magnetic fields with levels similar to those produced by high voltage overhead power lines. The main objective of these restrictions was to protect human health from the effects of MF produced by high voltage overhead transmission lines. The changed permissible level of MF intensity to the level now binding in different countries will have great economic and financial impact. The greatest impact will be observed in the already established residential areas, which require that the levels of magnetic field from existing overhead lines be lowered. The effects of more strict regulations on the protection against the effects of the 50 Hz magnetic field, reducing the levels to values lower than 0.25 A/m, can be grouped into three categories: technical effects, space and landscape implications and financial impact. The lowering of MF maximum acceptable level will require changes in the structure of new power lines and modifications in the existing grid. Unfortunately, the replacing of overhead power lines with cables is not possible on account of too high costs. The extension of the area, in which construction of dwelling houses will not be possible, can turn out to be the only solution.
NA61/SHINE (SHINE = SPS Heavy Ion and Neutrino Experiment) is an experiment at the CERN SPS using the upgraded NA49 hadron spectrometer. Among its physics goals are precise hadron production ...measurements for improving calculations of the neutrino beam flux in the T2K neutrino oscillation experiment as well as for more reliable simulations of cosmic-ray air showers. Moreover, p+p, p+Pb and nucleus+nucleus collisions will be studied extensively to allow for a study of properties of the onset of deconfinement and search for the critical point of strongly interacting matter. Currently NA61/SHINE uses the old NA49 software framework for reconstruction, simulation and data analysis. The core of this legacy framework was developed in the early 1990s. It is written in different programming and scripting languages (C, pgi-Fortran, shell) and provides several concurrent data formats for the event data model, which includes also obsolete parts. In this contribution we will introduce the new software framework, called Shine, that is written in C++ and designed to comprise three principal parts: a collection of processing modules which can be assembled and sequenced by the user via XML files, an event data model which contains all simulation and reconstruction information based on STL and ROOT streaming, and a detector description which provides data on the configuration and state of the experiment. To assure a quick migration to the Shine framework, wrappers were introduced that allow to run legacy code parts as modules in the new framework and we will present first results on the cross validation of the two frameworks.
The localization of high voltage objects, e.g., overhead transmission lines, under the spatial planning and environmental protection regulations is discussed. The most important elements of the ...localization procedure concerning high voltage overhead lines are presented. One of the elements of this procedure is the assessment of the investment environmental impact. The environmental audit is an essential document, in which this impact is described. It seems that its scope specified in the Environmental Protection Act is not adjusted to the specificity of line investments. This gives rise to some problems in preparing environmental audits for overhead lines, e.g., possible influence of high voltage lines on the Natura 2000 area zones. Several other related problems are also highlighted in this paper.
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