A Feshbach resonance occurs when the energy of two interacting free particles comes into resonance with a molecular bound state. When approaching this resonance, marked changes in the interaction ...strength between the particles can arise. Feshbach resonances provide a powerful tool for controlling the interactions in ultracold atomic gases, which can be switched from repulsive to attractive1, 2, 3, 4, and have allowed a range of many-body quantum physics effects to be explored5, 6. Here we demonstrate a Feshbach resonance based on the polariton spinor interactions in a semiconductor microcavity. By tuning the energy of two polaritons with anti-parallel spins across the biexciton bound state energy, we show an enhancement of attractive interactions and a prompt change to repulsive interactions. A mean-field two-channel model quantitatively reproduces the experimental results. This observation paves the way for a new tool for tuning polariton interactions and to move forward into quantum correlated polariton physics.
Background
Indications for hepatectomy in patients with hepatocellular carcinoma (HCC) who have portal hypertension (PH) have been controversial. Some studies have concluded that PH is a ...contraindication to hepatectomy, whereas others have suggested that perioperative prophylactic management (PPM) can help overcome complications after hepatectomy associated with PH. The objective of this retrospective study was to assess the short‐ and long‐term outcomes after hepatectomy for HCC in patients with PH, with or without PPM.
Methods
Records were reviewed of consecutive patients who underwent hepatectomy for HCC, with or without PPM of PH, in a single institution from 1994 to 2015. Patients were divided into three groups: those who received PPM for PH (PPM group), patients who had PH but did not receive PPM (no‐PPM group) and those without PH (no‐PH group).
Results
A total of 1259 patients were enrolled, including 123 in the PPM group, 181 in the no‐PPM group and 955 in the no‐PH group. Three‐ and 5‐year overall survival rates were 74·3 and 53·1 per cent respectively in the PPM group, 69·2 and 54·9 per cent in the no‐PPM group, and 78·1 and 64·2 per cent in the no‐PH group (P = 0·520 for PPM versus no PPM, P = 0·027 for PPM versus no PH, and P < 0·001 for no PPM versus no PH). Postoperative morbidity and mortality rates were 26·0 and 0·8 per cent respectively in the PPM group, 29·8 and 1·1 per cent in the no‐PPM group, and 20·3 and 0 per cent in the no‐PH group.
Conclusion
The present study has demonstrated acceptable outcomes among patients with HCC who received appropriate management for PH in an Asian population. Enhancement of the safety of hepatic resection through use of PPM may provide a rationale for expansion of indications for hepatectomy in patients with PH.
This study clarified the prognosis after hepatectomy in patients with hepatocellular carcinoma and portal hypertension. Enhancement of the safety of hepatic resection through use of perioperative prophylactic management may provide a rationale for expansion of indications for hepatectomy in patients with portal hypertension.
Portal hypertension is not a contraindication
An inverted-FL antenna is proposal with a self-complementary structure. This unique design is realized by integrating an inverted-F antenna with a self-complementary structure and an inverted-L ...element. The proposed antenna with a volume of 10 times 10 times 45 mm 3 achieves a constant impedance of 188 Omega without attaching a matching load required since a self-complementary antenna of an axially symmetric type has constant impedance. This antenna acquired broadband and multiband characteristics covering the GSM850/GSM900/DCS/ PCS/UMTS2100/UMTS2600 bands and the 2.5G/3.5G bands for Mobile-WiMAX by simulation and measurement.
Polaritonic Cross Feshbach Resonance Navadeh-Toupchi, M; Takemura, N; Anderson, M D ...
Physical review letters,
2019-Feb-01, Letnik:
122, Številka:
4
Journal Article
Recenzirano
Odprti dostop
We demonstrate the existence of a cross Feshbach resonance by strongly driving a lower polariton mode and by monitoring in time the transmission of a short optical pulse at the energy of the upper ...polariton mode in a semiconductor microcavity. From the signatures of the optical resonance, strength, and sign of the energy shift, we attribute the origin of the scattering process between polariton modes with opposite circular polarization to a biexciton bound state. From this study, we infer the conditions required for a strong enhancement of the generation of entangled photon pairs.
Previous studies suggest that increased learning satisfaction may encourage learning engagement in an online learning environment.
To evaluate the level of learning engagement and its relationship ...with students' perceived learning satisfaction in an online clinical nursing elective course.
A prospective interventional study.
A nursing course was converted to an online format because of the coronavirus disease COVID pandemic.
Part-time post-registration nursing undergraduates enrolled in an elective online clinical course.
Related teaching and learning strategies were deployed in the course using the Community of Inquiry framework. All students who completed the course were invited to complete an online survey that included a validated Online Student Engagement questionnaire (OSE). Pearson's correlations were used to determine the association between perceived learning satisfaction and learning engagement. A logistic regression model was used to explore the associations of gender, age, working experience and perceived learning satisfaction with higher learning engagement.
The questionnaires were completed by 56 of 68 students (82%). The Pearson's correlation coefficient between the mean perceived learning satisfaction and OSE scores was 0.75 (p < .001). Twenty-five students (45%) were identified as highly engaged, using a cut-off of ≥3.5 for the mean OSE score. The mean perceived learning satisfaction (SD) score differed significantly between highly engaged and not highly engaged students 4.02 (0.49) vs. 3.27 (0.62), p < .001. The logistic regression model showed that a greater perceived learning satisfaction adjusted odds ratio (OR): 17.2, 95% C.I.: 3.46–86.0, p = .001 was associated with an increased likelihood of higher learning engagement, and >1 year of working experience (adjusted OR: 0.11, 95% C.I.: 0.01–0.89, p = .0039) was associated with a decreased likelihood of higher learning engagement.
The study findings suggest that perceived learning satisfaction predicts learning engagement among nursing students in this online learning course.
To investigate the association between plasma N-terminal pro-atrial natriuretic peptide concentration and glomerular filtration rate in dogs.
Dogs were classified into four categories by bodyweight. ...Dogs were divided into four groups (Groups 1 to 4) based on glomerular filtration rate estimates using plasma iohexol clearance per bodyweight category. Generalised linear models were built to explore the relationship between plasma N-terminal pro-atrial natriuretic peptide concentration and glomerular filtration rate and the effect of confounders on plasma N-terminal pro-atrial natriuretic peptide concentration.
Fifty-three dogs were included (Group 1, 25; Group 2, seven; Group 3, five; and Group 4, 16). The medians (interquartile range) N-terminal pro-atrial natriuretic peptide concentrations for Groups 1 to 4 were 7224 pg/mL (4766 to 10,254 mg/dL), 8958 pg/mL (4935 to 11,271 mg/dL), 9280 pg/mL (9195 to 10,384 mg/dL) and 12,683 pg/mL (9133 to 19,217 mg/dL), respectively. Group 4, estimated to have the highest reduction in glomerular filtration rate, had a higher plasma N-terminal pro-atrial natriuretic peptide concentration than Groups 1 to 3. Based on the final generalised linear model, influencing factors for plasma N-terminal pro-atrial natriuretic peptide concentration were plasma iohexol clearance (-0.136; 95% confidence interval, -0.227 to -0.046) and bodyweight (-0.058; 95% confidence interval, -0.098 to -0.018).
N-terminal pro-atrial natriuretic peptide concentration is associated with the glomerular filtration rate.
Proteinuria is a recognized risk factor for progression of canine chronic kidney disease (CKD). However, the prognosis of non-azotemic proteinuric CKD in dogs has been studied only to a limited ...extent. Moreover, the degree to which proteinuria should be decreased to delay CKD progression remains unknown. The purposes of this study were (1) to identify factors associated with disease progression and (2) to investigate the degree of proteinuria, albuminuria, and blood pressure during the course of treatment associated with the progression using time-averaged urine protein:creatinine ratio (UPC) and urine albumin:creatinine ratio (UAC) in canine non-azotemic proteinuric CKD. Twenty-one dogs with non-azotemic proteinuric CKD were included in the study. High UPC and UAC were associated with CKD progression (P < .05). Time-averaged high UPC and UAC were significantly related to progression (P < .05). The cutoff values of these time-averaged parameters for predicting the progression were 4.1 and 2.0, respectively. In dogs with non-azotemic proteinuric CKD, more severe proteinuria and albuminuria were associated with progression. The present study suggests that because UPC ≥ 4.1 and UAC ≥ 2.0 during treatment were associated with a faster progression of non-azotemic proteinuric CKD, therapeutic intervention is warranted.
•Outcome of canine non-azotemic proteinuric chronic kidney disease was investigated.•Proteinuria and albuminuria were associated with the progression of kidney disease.•UPC ≥4.1 and UAC ≥2.0 during treatment can relate with the faster progression.
Nonlinear dynamical systems involving small populations of individuals may sustain oscillations in the population densities arising from discrete changes in population numbers due to random events. ...By applying these ideas to nanolasers operating with small numbers of emitting dipoles and photons at threshold, we show that such lasers should display photon and dipole population cycles above threshold, which should be observable as a periodic modulation in the second-order correlation function of the nanolaser output. Such a modulation was recently reported in a single-mode vertical-cavity surface-emitting semiconductor laser.
Objectives
To examine the relationship between fibroblast growth factor‐23 levels, chronic kidney disease severity and mineral metabolic disorders associated to chronic kidney disease in dogs.
...Materials and Methods
Fifteen control and 75 chronic kidney disease dogs were retrospectively included. Serum fibroblast growth factor‐23 concentration and other phosphate metabolite parameters were compared between controls and each International Renal Interest Society stage. Multiple regression analysis was performed to determine the predictors of fibroblast growth factor‐23.
Results
Serum fibroblast growth factor‐23 concentrations were significantly higher in dogs with IRIS stages 2, 3 and 4 chronic kidney disease than those in dogs in control group and with stage 1 and increased along with the severity of chronic kidney disease. Compared with control dogs, serum intact parathyroid hormone significantly increased from stage 2 and serum phosphorus concentrations increased in dogs with stage 4. In dogs with stage 2, fibroblast growth factor‐23 levels significantly increased in those with hyperphosphatemia compared with those with normophosphatemia. While eight of 26 (30.8%) dogs with stage 2 developed hyperparathyroidism (intact parathyroid hormone>8.5 ng/L), 19 (73.1%) dogs with stage 2 had elevated fibroblast growth factor‐23 levels above the reference range (>528 pg/mL). Log creatinine, log intact parathyroid hormone and log product of total calcium and phosphorus were independent predictors of log fibroblast growth factor‐23.
Clinical Significance
This preliminary study suggests that canine fibroblast growth factor‐23 might be involved in mineral metabolic disorders associated to chronic kidney disease in dogs, and this factor could be potentially used as an early marker for this condition.
Background
Peritoneal or thoracoabdominal wall implants from hepatocellular carcinoma (HCC) occur occasionally after biopsy, percutaneous therapy or resection, and spontaneously, with no effective ...treatment available. The objective of this study was to clarify the indications for, and benefits of, surgical resection of such HCC implants.
Methods
This was a retrospective analysis of patients who underwent resection for peritoneal or chest wall implants from HCC over 14 years (1997–2011). Indications for surgery for implanted HCC were: limited number of implanted lesions including those found incidentally during surgery; intrahepatic lesion absent or predicted to be locally controllable; and absence of ascites with sufficient hepatic functional reserve. Prognostic factors affecting survival after resection were determined by univariable and multivariable analysis.
Results
A total of 32 patients underwent 36 resections. Cumulative 1‐, 3‐ and 5‐year overall survival rates were 71, 44 and 39 per cent respectively, with a median survival time of 34·5 months. Univariable and multivariable analysis revealed that poor perioperative intrahepatic disease control was associated with poor survival.
Conclusion
Surgical resection of implanted HCC may improve long‐term survival in selected patients as long as intrahepatic disease is absent or well controlled.
Useful in selected cases
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