A study was made of the time of formation and the rate of propagation of bacterial population waves as dependent on substrate concentration. Experimentally and theoretically it is shown that the time ...of bacterial wave formation grows with increasing concentration of the nutritive component. At the same time, the wave propagation rate drops at relatively high concentrations of the nutritive component. In numerical experiments with a mathematical model, comparative analysis has been made of the dynamics of the behavior of bacterial waves at different chemotactic responses.
A natural avermectin complex, aversectin C, was shown to be capable of exerting selective cytostatic and neurotoxic effects on mammalian cells. Specifically, it killed proliferating neuroblastoma ...B103 cells but was non-toxic for differentiated cells of this culture. The antiproliferation action of aversectin C was not inhibited by bicuculline or picrotoxin, antagonists of the GABAalpha receptors, and was partly due to the action of avermectin A1, a component of aversectin C. Aversectin C irreversibly suppressed activity of 60% neurons in medial septal slices of the rat brain. More than 55% of them were the GABAalpha- and B1-sensitive neurons whereas the rest, about 45% neurons, were the GABAalpha-insensitive and the neurotoxic effect of aversectin C was caused mainly by the B2 component.
A natural avermectin complex, aversectin C, was shown to be capable of exerting selective cytostatic effect. It killed proliferating neuroblastoma B 103 cells but was non-toxic for differentiated ...cells of this culture. The activity of aversectin C was related neither to activation of the GABA alpha-receptors nor to their blocking and was at a large extent due to the action of avermectin A1, a component of aversectin C.
A method for enteral catheter feeding is suggested. It was applied in 60 patients after esophagoplasty. The main group consisted of 23 females and 37 males aged from 18 to 68 years. Esophageal ...carcinoma was observed in 31, burn stricture of the esophagus 18, and other benign diseases of the esophagus in 11 cases. All patients were subjected to extirpation of the esophagus with one-stage posteromedial esophagoplasty in 57 patients with an isoperistaltic gastric tube and in 3 patients with the colon. The control group was formed of 20 patients who underwent the same operations. Inpitan, ovolact, and hypernutril were used for enteral catheter feeding. The catheter was introduced via the nasal passage and transplant into the proximal segment of the jejunum. The mixtures were administered in drops of 5 to 7 days after the operation. Only parenteral feeding was conducted in the control group. The disorders of the alimentary status were removed quicker in patients of the main group than in the control and the incidence of postoperative complications was less. Body weight and the nitrogen balance were restored within a shorter time in the main group patients and incompetence of the esophageal anastomoses developed in a lesser number of cases.
The state of the cardiovascular system was studied over time in 171 patients with a history of acute impairment of the brain circulation; 135 of them were suffering from coronary heart disease (CHD) ...(the study group) and 35 patients were free of CHD (the control group). The majority of the study group patients showed little if any clinical manifestations of CHD in the acute period of cerebral stroke. Five (3.7%) patients displayed small focal myocardial infarction on the ECG, two showed focal dystrophy of the myocardium, 71 (52.2%) patients had compromised coronary circulation and 47.5% of the patients had various disorders of rhythm and conductivity. The impairment of the coronary circulation in the acute period of cerebral stroke was shown to correlate with a subsequent course of CHD.
After exposure to transverse accelerations of 4-10 g changes in the vascular system of the eye and immunobiological resistance of the body persisted from 5 to 15 days. The data give evidence that the ...state of retinal vessels is the most informative index of the cumulative effect on the body and its recovery.
