Skin resurfacing is a vital component to an overall, global strategy for comprehensive facial rejuvenation that would include facial lifting procedures to counteract gravity, volume restoration to ...combat soft-tissue depletion associated with aging, and other ancillary modalities, like botulinum toxin and dermal fillers. Skin resurfacing can be divided into two principal categories: ablative and non-ablative. Non-ablative therapies include laser, light, and radiofrequency treatments in which the epidermis is not violated, thereby limiting recovery time but which would also potentially be less effective compared with ablative therapies. Ablative skin resurfacing entails a treatment modality (chemical, laser, and/or mechanical) that removes the overlying epidermis and partial thickness of the dermal layer in order to elicit the desired rejuvenation. By their very nature, ablative therapies require a convalescence of varying duration when the individual will not look socially acceptable. The myriad ablative skin options carry with them unique profiles that include the extent of rejuvenation, viz., the capacity to eliminate rhytids, improve dyschromias and other skin abnormalities, and a proportionate degree of recovery time depending on the depth of imparted injury.
Plasma Skin Resurfacing Lam, Samuel M.; Tzikas, Thomas L.
Simplified Facial Rejuvenation
Book Chapter
Traditional ablative techniques, including CO2 laser resurfacing, medium-to-deep chemical peeling, and mechanical dermabrasion, have provided excellent and durable skin rejuvenation results. However, ...each treatment modality carries with it a potential morbidity profile and/or aesthetic limitations. Lighter treatment therapies like 35% trichloroacetic acid (TCA) peeling can rejuvenate mildly sun-damaged skin including dyschromias and fine rhytids, but may fail to correct deeper rhytids and more profound skin textural problems. Deeper treatments like CO2 laser resurfacing and phenol can correct deeper rhytids but are associated with a more significantly protracted recovery period and risk of hypopigmentation. Mechanical dermabrasion works well to correct discrete contour problems like acne scarring and perioral rhytids but is technically more difficult to achieve consistency across the entire face when used as a standalone treatment modality. Obviously, a combination approach toward skin rejuvenation using various modalities can optimize aesthetic improvement while minimizing the side-effect profile.
Bayesian regression of functional neuroimages Tzikas, Dimitris G.; Likas, Aristidis; Galatsanos, Nikolas P. ...
2004 12th European Signal Processing Conference,
2004-Sept., 20040901
Conference Proceeding, Journal Article
A Bayesian approach is proposed for statistical analysis of fMRI data sets in a two state ("on-off") activation study. The approach is based on the Relevance Vector Machine (RVM) regression ...framework. According to this approach the shape of the activations is a superposition of kernel functions, one at each pixel of the image, and a hierarchical Bayesian model is employed which imposes a sparse representation by selecting a number relevant kernel functions. We have implemented an incremental method for constructing the RVM model and, in addition, we have employed a cross-validation criterion to deal with the problem of kernel width selection. The proposed method allows the accurate estimation of the activation locations when correlated noise is present even at low signal-to-noise ratios. We tested this method using an artificial phantom derived from a previous neuroimaging study with promising results compared with previous approaches.
Sizing for transcutaneous aortic valve replacement (TAVI) relies on non-invasive imaging. Incorrect sizing may result in adverse outcomes including paraprosthetic regurgitation, asymmetrical ...expansion which may impair prosthesis durability and, in the case of severe sizing errors, device embolisation or aortic root rupture. This review addresses the optimal approach for sizing. It is based on currently available data including the anatomical implications of using different imaging modalities, the steps of how to reproducibly measure the correct annulus diameter on MSCT, and current evidence for different sizing strategies.
The influence of this Thomas Bayes' work was immense. It was from here that "Bayesian" ideas first spread through the mathematical world, as Bayes's own article was ignored until 1780 and played no ...important role in scientific debate until the 20th century. It was also this article of Laplace's that introduced the mathematical techniques for the asymptotic analysis of posterior distributions that are still employed today. And it was here that the earliest example of optimum estimation can be found, the derivation and characterization of an estimator that minimized a particular measure of posterior expected loss. After more than two centuries, we mathematicians, statisticians cannot only recognize our roots in this masterpiece of our science, we can still learn from it.
Six groups of rats consisting of twelve each were used to evaluate the tensile strength of the skin wound at an early healing period. Effects of Zyplast implant and platelet-derived growth factor on ...the tensile strength of wounds created on the backs of rats were studied. The results indicate that, the addition of Zyplast to the wounds resulted in significantly lower tensile strength in wounds closed with or without tension as compared to controls. The addition of platelet-derived growth factor to Zyplast treated wounds resulted in significantly higher tensile strength overall as compared to Zyplast treated groups alone. The negative effect of Zyplast on wounds closed with or without tension were overcome by widespread positive effects of platelet-derived growth factor on wound healing.< >
