Prevalence of neurological involvement in Behçet's disease (BD) varies between studies and is associated with high morbimortality. Neurological involvement is classified as parenchymal and ...non-parenchymal involvement (vascular involvement). Treatment of neurological involvement consists of immunosuppressants. Evidence regarding presentation and outcomes in neuro-Behçet's (NB) is scarce.
Observational retrospective study that included consecutive patients diagnosed with BD between 2006 and 2019 in a tertiary hospital of Madrid.
Fifty-seven patients were included with a mean follow-up of 7.83 (±6.98) years. The mean age at diagnosis of BD and first NB episode was 34.7 (± 12.1) and 31.03 (±9.9) years, respectively. Fifty-six NB episodes were registered in 25 patients. Fever (OR 3.39, CI 95% 1.14-10.15) and pseudofolliculitis (OR 4.06, CI 95% 1.11-14.80) were associated to NB. Trigeminal neuralgia was found in 16% (4/25) of patients.
The prevalence of NB in patients with BD was higher than previously described. Fever and pseudofolliculitis were more frequently associated with NB, with low mortality during follow-up.
Prevalence of neurological involvement in Behçet's disease (BD) varies between studies and is associated with high morbimortality. Neurological involvement is classified as parenchymal and ...non-parenchymal involvement (vascular involvement). Treatment of neurological involvement consists of immunosuppressants. Evidence regarding presentation and outcomes in neuro-Behçet's (NB) is scarce.
Observational retrospective study that included consecutive patients diagnosed with BD between 2006 and 2019 in a tertiary hospital of Madrid.
Fifty-seven patients were included with a mean follow-up of 7.83 (±6.98) years. The mean age at diagnosis of BD and first NB episode was 34.7 (±12.1) and 31.03 (±9.9) years, respectively. Fifty-six NB episodes were registered in 25 patients. Fever (OR 3.39, 95% CI: 1.14–10.15) and pseudofolliculitis (OR 4.06, 95% CI: 1.11–14.80) were associated to NB. Trigeminal neuralgia was found in 16% (4/25) of patients.
The prevalence of NB in patients with BD was higher than previously described. Fever and pseudofolliculitis were more frequently associated with NB, with low mortality during follow-up.
Las manifestaciones neurológicas en la enfermedad de Behçet (EB) presentan una prevalencia variable en la literatura y asocian una mayor morbimortalidad. Se distingue la afectación parenquimatosa y la no parenquimatosa (vascular). El tratamiento de estas manifestaciones se basa en la inmunosupresión. La evidencia sobre la presentación y evolución del neurobehçet (NB) es escasa.
Estudio observacional retrospectivo que incluyó a pacientes consecutivos con diagnóstico de EB entre 2006 y 2019 en un hospital terciario de Madrid.
Se incluyó a 57 pacientes con EB, con un seguimiento medio de 7,83 (±6,98) años. La edad media al diagnóstico de EB y del primer episodio de NB fue 34,7 (±12,1) años y 31 (±9,9) años, respectivamente. Se registraron 56 episodios de NB en 25 pacientes. La fiebre (OR 3,39; IC 95%: 1,14-10,15) y la pseudofoliculitis (OR 4,06; IC 95%: 1,11-14,80) se asociaron a NB. La neuralgia del trigémino se encontró en el 16% (4/25) de los pacientes.
La prevalencia de NB fue mayor que la descrita previamente. La fiebre y la pseudofoliculitis se asociaron a NB y la mortalidad fue baja durante el seguimiento.
