Worm variation made accessible Snoek, L Basten; Joeri van der Velde, K; Li, Yang ...
Worm (Austin, TX),
2014, Letnik:
3, Številka:
2
Journal Article
Odprti dostop
In Caenorhabditis elegans, the recent advances in high-throughput quantitative analyses of natural genetic and phenotypic variation have led to a wealth of data on genotype phenotype relations. This ...data has resulted in the discovery of genes with major allelic effects and insights in the effect of natural genetic variation on a whole range of complex traits as well as how this variation is distributed across the genome. Regardless of the advances presented in specific studies, the majority of the data generated in these studies had yet to be made easily accessible, allowing for meta-analysis. Not only data in figures or tables but meta-data should be accessible for further investigation and comparison between studies. A platform was created where all the data, phenotypic measurements, genotypes, and mappings can be stored, compared, and new linkages within and between published studies can be discovered. WormQTL focuses on quantitative genetics in Caenorhabditis and other nematode species, whereas WormQTL
HD
quantitatively links gene expression quantitative trait loci (eQTL) in C. elegans to gene-disease associations in humans.
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