Acrylic resins are widely used in the fabrication of denture bases and have been shown to be cytotoxic as a result of substances that leach from the resin. The primary eluate is residual monomer. ...Numerous reports suggest that residual monomer may be responsible for mucosal irritation and sensitization of tissues. This information is important, not only to assess the biologic effects of such materials, but also to enable a comparison among the different polymerization methods, thus assisting the clinician in selecting a material with minimal cytotoxicity. This article reviews the literature published from 1973 to 2000, selected by use of a Medline search, associated with cytotoxic effects usually ascribed to acrylic denture base materials.
Objectives
The morphology and chemical composition of enamel submitted to different sterilization methods was studied.
Methods
X-ray photoelectron spectroscopy (XPS), field emission gun scanning ...electron microscopy (FEG-SEM), and energy-dispersive X-ray spectroscopy (EDS) were performed to evaluate 50 bovine enamel specimens sterilized using four methods: microwaving (MI), gamma irradiation (GI), ethylene oxide (EO), and steam autoclave (SA). Non-sterilized specimens were used as control.
Results
XPS indicated that the concentration of P (phosphorus), CO
3
(carbonate), and CO
3
/P was not changed in all groups. GI produced no significant change on elemental composition. SA produced the major decrease in calcium (Ca), Ca/P ratio, and increase in N (nitrogen). MI was found to decrease Ca, Ca/P ratio and O (oxygen), and increase in C (carbon) and N. EO produced decrease in Ca and O with increased C concentration. FEG-SEM revealed surface and in-depth morphological changes on SA specimens. Minor surface alterations were observed for EO and for MI groups, and no alteration was observed on GI group. EDS indicated no difference on elemental composition of enamel bulk among groups.
Conclusions
SA produced mineral loss and morphological alterations on surface and in depth. MI and EO sterilization caused mineral loss showing only slight alteration on enamel surface. GI sterilization preserves the morphological characteristics of enamel. The sterilization methods could be classified from lower to high damage as GI < MI < EO < SA.
Clinical relevance
This is a comprehensive comparative study where different methods for enamel sterilization were investigated in terms of chemical changes. The results presented here may help researchers to choose the most appropriate method for their research setting and purpose.
The merger of two neutron stars is predicted to give rise to three major detectable phenomena: a short burst of γ-rays, a gravitational-wave signal, and a transient optical-near-infrared source ...powered by the synthesis of large amounts of very heavy elements via rapid neutron capture (the r-process). Such transients, named 'macronovae' or 'kilonovae', are believed to be centres of production of rare elements such as gold and platinum. The most compelling evidence so far for a kilonova was a very faint near-infrared rebrightening in the afterglow of a short γ-ray burst at redshift z = 0.356, although findings indicating bluer events have been reported. Here we report the spectral identification and describe the physical properties of a bright kilonova associated with the gravitational-wave source GW170817 and γ-ray burst GRB 170817A associated with a galaxy at a distance of 40 megaparsecs from Earth. Using a series of spectra from ground-based observatories covering the wavelength range from the ultraviolet to the near-infrared, we find that the kilonova is characterized by rapidly expanding ejecta with spectral features similar to those predicted by current models. The ejecta is optically thick early on, with a velocity of about 0.2 times light speed, and reaches a radius of about 50 astronomical units in only 1.5 days. As the ejecta expands, broad absorption-like lines appear on the spectral continuum, indicating atomic species produced by nucleosynthesis that occurs in the post-merger fast-moving dynamical ejecta and in two slower (0.05 times light speed) wind regions. Comparison with spectral models suggests that the merger ejected 0.03 to 0.05 solar masses of material, including high-opacity lanthanides.
summary This investigation evaluated the effectiveness of an infection control protocol for cleansing and disinfecting removable dental prostheses. Sixty‐four dentures were rubbed with sterile ...cotton swab immediately after they had been taken from patients' mouths. Samples were individually placed in the culture medium and immediately incubated at 37 ± 2 °C. The dentures were scrubbed for 1 min with 4% chlorhexidine, rinsed for 1 min in sterile water and placed for 10 min in one of the following immersion solutions: 4% chlorhexidine gluconate, 1% sodium hypochlorite, Biocide (iodophors) and Amosan (alkaline peroxide). After the disinfection procedures, the dentures were immersed in sterile water for 3 min, reswabbed and the samples were incubated. All samples obtained in the initial culture were contaminated with micro‐organisms. All the lower dentures immersed in Biocide showed positive growth, and the upper dentures were positive for growth in six of eight dentures. The 4% chlorhexidine gluconate, 1% sodium hypochlorite and Amosan solutions have been proved effective to reduce the growth of the micro‐organisms in the 10 min immersion period. The protocol evaluated in this study seems to be a viable method to prevent cross‐contamination between dental personnel and patients.
Abstract Objectives This study evaluated the effect of water-bath post-polymerization at 55 °C for 10 min (WB) on the content and leaching of residual compounds, degree of conversion, flexural ...strength, and hardness of hard chairside reline resins (Kooliner: K, New Truliner: N, Ufi Gel hard: U, and Tokuso Rebase Fast: T). Methods Leaching experiments were made by storing specimens ( n = 48) in artificial saliva at 37 ± 1 °C and analyzing residual monomers and plasticizer by HPLC. Analysis of residual monomer and plasticizer content ( n = 48) was also made by HPLC. Degree of conversion ( n = 40) was analyzed by using FT-Raman spectroscopy. A 3-point loading test was used to evaluate the flexural strength of the specimens ( n = 80). One fragment of each flexural test specimen was then submitted to Vickers microhardness test. Results WB produced a significant decrease ( p < 0.050) in the amount of residual compounds eluted from the materials within the first hour of immersion. With the exception of material U, WB decreased the duration of release of the residual compounds evaluated. All materials evaluated exhibited significantly ( p < 0.050) lower values of residual monomer and plasticizer (material N) after WB compared with the control groups. WB increased the degree of conversion of K and T resins and the hardness of N, K, and T resins ( p < 0.050). Only material K showed an increase in flexural strength after WB ( p < 0.050). Significance Immersion of relined dentures in water at 55 °C for 10 min can be used to reduce the amounts and duration of release of residual compounds and improve mechanical properties of some of the materials evaluated.
The Atacama Large Millimeter Array (ALMA) Large Program to INvestigate CII at Early times (ALPINE) targets the CII 158
μ
m line and the far-infrared continuum in 118 spectroscopically confirmed ...star-forming galaxies between
z
= 4.4 and
z
= 5.9. It represents the first large CII statistical sample built in this redshift range. We present details regarding the data processing and the construction of the catalogs. We detected 23 of our targets in the continuum. To derive accurate infrared luminosities and obscured star formation rates (SFRs), we measured the conversion factor from the ALMA 158
μ
m rest-frame dust continuum luminosity to the total infrared luminosity (
L
IR
) after constraining the dust spectral energy distribution by stacking a photometric sample similar to ALPINE in ancillary single-dish far-infrared data. We found that our continuum detections have a median
L
IR
of 4.4 × 10
11
L
⊙
. We also detected 57 additional continuum sources in our ALMA pointings. They are at a lower redshift than the ALPINE targets, with a mean photometric redshift of 2.5 ± 0.2. We measured the 850
μ
m number counts between 0.35 and 3.5 mJy, thus improving the current interferometric constraints in this flux density range. We found a slope break in the number counts around 3 mJy with a shallower slope below this value. More than 40% of the cosmic infrared background is emitted by sources brighter than 0.35 mJy. Finally, we detected the CII line in 75 of our targets. Their median CII luminosity is 4.8 × 10
8
L
⊙
and their median full width at half maximum is 252 km s
−1
. After measuring the mean obscured SFR in various CII luminosity bins by stacking ALPINE continuum data, we find a good agreement between our data and the local and predicted SFR–
L
CII
relations.
We present the ancillary data and basic physical measurements for the galaxies in the ALMA Large Program to Investigate C+ at Early Times (ALPINE) survey-the first large multiwavelength survey that ...aims at characterizing the gas and dust properties of 118 main-sequence galaxies at redshifts 4.4 < z < 5.9 via the measurement of emission at (64% at >3.5 ) and the surrounding far-infrared continuum in conjunction with a wealth of optical and near-infrared data. We outline in detail the spectroscopic data and selection of the galaxies as well as the ground- and space-based imaging products. In addition, we provide several basic measurements including stellar masses, star formation rates (SFR), rest-frame ultra-violet (UV) luminosities, UV continuum slopes (β), and absorption line redshifts, as well as H emission derived from Spitzer colors. We find that the ALPINE sample is representative of the 4 < z < 6 galaxy population selected by photometric methods and only slightly biased toward bluer colors (Δβ ∼ 0.2). Using as tracer of the systemic redshift (confirmed for one galaxy at z = 4.5 out of 118 for which we obtained optical λ3727 emission), we confirm redshifted Ly emission and blueshifted absorption lines similar to findings at lower redshifts. By stacking the rest-frame UV spectra in the rest frame, we find that the absorption lines in galaxies with high specific SFR are more blueshifted, which could be indicative of stronger winds and outflows.
summary The disinfection of dental prostheses by immersion in a chemical solution should be capable of rapid inactivation of pathogenic microorganisms, without causing any adverse effect on the ...denture base resins. This study evaluated the effect of disinfection immersion on the transverse strength of two heat‐cured resins. The denture base resins (Lucitone 550 and QC 20) were polymerized according to the manufacturers' instructions. After polymerization, the specimens were polished, and then stored in water at 37 °C for 50 ± 2 h prior immersion in one of the following solutions for 10 min: 4% chlorhexidine, 1% sodium hypochlorite and 3·78% sodium perborate. The specimens were submitted to disinfection twice, simulating when dentures come from the patient and before being returned to the patient. Ten specimens were made for each group. The transverse strength was evaluated by a 3‐point bend test. The flexural strength of the two denture base acrylic resins evaluated remained unaffected after immersion in the three solutions evaluated. In general, the QC 20 resin specimens exhibited lower transverse strength than the Lucitone 550 resin specimens, regardless of immersion solutions.
Abstract
The low distance, z = 0.0591, of GRB 100316D and its association with SN 2010bh represent two important motivations for studying this host galaxy and the GRB's immediate environment with the ...integral field spectrographs like Very Large Telescope/Multi-Unit Spectroscopic Explorer. Its large field of view allows us to create 2D maps of gas metallicity, ionization level and the star formation rate (SFR) distribution maps, as well as to investigate the presence of possible host companions. The host is a late-type dwarf irregular galaxy with multiple star-forming regions and an extended central region with signatures of on-going shock interactions. The gamma-ray burst (GRB) site is characterized by the lowest metallicity, the highest SFR and the youngest (∼20–30 Myr) stellar population in the galaxy, which suggest a GRB progenitor stellar population with masses up to 20–40 M⊙. We note that the GRB site has an offset of ∼660 pc from the most luminous SF region in the host. The observed SF activity in this galaxy may have been triggered by a relatively recent gravitational encounter between the host and a small undetected (LH α ≤ 1036 erg s−1) companion.
We study the efficiency of galactic feedback in the early Universe by stacking the C II 158
μ
m emission in a large sample of normal star-forming galaxies at 4 <
z
< 6 from the ALMA Large Program ...to INvestigate C II at Early times (ALPINE) survey. Searching for typical signatures of outflows in the high-velocity tails of the stacked C II profile, we observe (i) deviations from a single-component Gaussian model in the combined residuals and (ii) broad emission in the stacked C II spectrum, with velocities of |
v
|≲500 km s
−1
. The significance of these features increases when stacking the subset of galaxies with star formation rates (SFRs) higher than the median (SFR
med
= 25
M
⊙
yr
−1
), thus confirming their star-formation-driven nature. The estimated mass outflow rates are comparable to the SFRs, yielding mass-loading factors of the order of unity (similarly to local star-forming galaxies), suggesting that star-formation-driven feedback may play a lesser role in quenching galaxies at
z
> 4. From the stacking analysis of the datacubes, we find that the combined C II core emission (|
v
|< 200 km s
−1
) of the higher-SFR galaxies is extended on physical sizes of ∼30 kpc (diameter scale), well beyond the analogous C II core emission of lower-SFR galaxies and the stacked far-infrared continuum. The detection of such extended metal-enriched gas, likely tracing circumgalactic gas enriched by past outflows, corroborates previous similar studies, confirming that baryon cycle and gas exchanges with the circumgalactic medium are at work in normal star-forming galaxies already at early epochs.
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