Swift intensive accretion disk reverberation mapping of four AGN yielded light curves sampled ∼200-350 times in 0.3-10 keV X-ray and six UV/optical bands. Uniform reduction and cross-correlation ...analysis of these data sets yields three main results: (1) The X-ray/UV correlations are much weaker than those within the UV/optical, posing severe problems for the lamp-post reprocessing model in which variations in a central X-ray corona drive and power those in the surrounding accretion disk. (2) The UV/optical interband lags are generally consistent with as predicted by the centrally illuminated thin accretion disk model. While the average interband lags are somewhat larger than predicted, these results alone are not inconsistent with the thin disk model given the large systematic uncertainties involved. (3) The one exception is the U band lags, which are on average a factor of ∼2.2 larger than predicted from the surrounding band data and fits. This excess appears to be due to diffuse continuum emission from the broad-line region (BLR). The precise mixing of disk and BLR components cannot be determined from these data alone. The lags in different AGN appear to scale with mass or luminosity. We also find that there are systematic differences between the uncertainties derived by JAVELIN versus more standard lag measurement techniques, with JAVELIN reporting smaller uncertainties by a factor of 2.5 on average. In order to be conservative only standard techniques were used in the analyses reported herein.
Summary
Background Dermoscopy is a noninvasive technique that enables the clinician to perform direct microscopic examination of diagnostic features, not seen by the naked eye, in pigmented skin ...lesions. Diagnostic accuracy of dermoscopy has previously been assessed in meta‐analyses including studies performed in experimental and clinical settings.
Objectives To assess the diagnostic accuracy of dermoscopy for the diagnosis of melanoma compared with naked eye examination by performing a meta‐analysis exclusively on studies performed in a clinical setting.
Methods We searched for publications from 1987 to January 2008 and found nine eligible studies. The selected studies compare diagnostic accuracy of dermoscopy with naked eye examination using a valid reference test on consecutive patients with a defined clinical presentation, performed in a clinical setting. Hierarchical summary receiver operator curve analysis was used to estimate the relative diagnostic accuracy for clinical examination with, and without, the use of dermoscopy.
Results We found the relative diagnostic odds ratio for melanoma, for dermoscopy compared with naked eye examination, to be 15·6 95% confidence interval (CI) 2·9–83·7, P = 0·016; removal of two outlier studies changed this to 9·0 (95% CI 1·5–54·6, P = 0·03).
Conclusions Dermoscopy is more accurate than naked eye examination for the diagnosis of cutaneous melanoma in suspicious skin lesions when performed in the clinical setting.
Black hole masses of the highest redshift quasars (4 ~ z ~ 6) are estimated using a previously presented scaling relationship, derived from reverberation mapping of nearby quasars, and compared with ...quasars at lower redshift. It is shown that the central black holes in luminous z > ~ 4 quasars are very massive (> ~10 super(9) M sub(o)). It is argued that the mass estimates of the high-redshift quasars are not subject to larger uncertainties than those for nearby quasars. Specifically, the large masses are not overestimates, and the lack of similarly large black hole masses in the nearby universe does not rule out their existence at high redshift. However, active galactic nucleus host galaxies do not typically appear fully formed and/or evolved at these early epochs. This supports scenarios in which black holes build up mass very fast in a radiatively inefficient (or obscured) phase relative to the stars in their galaxies. In addition, upper envelopes of M sub(BH) ~ 10 super(10) M sub(o) and L sub(bol) ~ 10 super(48) ergs s super(-1) are observed at all redshifts.
Context: .Scatter around the relationship between central black hole masses in active galactic nuclei (AGNs) obtained by reverberation-mapping methods and host-galaxy bulge velocity dispersion ...indicates that the masses are uncertain typically by a factor of about three. Aims: .In this paper, we try to identify the sources and systematics of this uncertainty. Methods: .We characterize the broad Hbeta emission-line profiles by the ratio of their full-width at half maximum (FWHM) to their line dispersion, i.e., the second moment of the line profile. We use this parameter to separate the reverberation-mapped AGNs into two populations, the first with narrower Hbeta lines that tend to have relatively extended wings, and the second with broader lines that are relatively flat-topped. The first population is characterized by higher Eddington ratios than the second. Within each population, we calibrate the black-hole mass scale by comparison of the reverberation-based mass with that predicted by the bulge velocity dispersion. We also use the distribution of ratios of the reverberation-based mass to the velocity-dispersion mass prediction in a comparison with a "generalized thick disk" model in order to see if inclination can plausibly account for the observed distribution. Results: .We find that the line dispersion is a less biased parameter in general than FWHM for black hole mass estimation, although we show that it is possible to empirically correct for the bias introduced by using FWHM to characterize the emission-line width. We also argue that inclination effects are apparent only in some small subset of the reverberation-based mass measurements; it is primarily the objects with the narrowest emission lines that seem to be most strongly affected. Conclusions: .Our principal conclusion is that the Hbeta profile is sensitive primarily to Eddington ratio, but that inclination effects play a role in some cases.
Swift monitoring of NGC 4151 with an ∼6 hr sampling over a total of 69 days in early 2016 is used to construct light curves covering five bands in the X-rays (0.3-50 keV) and six in the ultraviolet ...(UV)/optical (1900-5500 Å). The three hardest X-ray bands (>2.5 keV) are all strongly correlated with no measurable interband lag, while the two softer bands show lower variability and weaker correlations. The UV/optical bands are significantly correlated with the X-rays, lagging ∼3-4 days behind the hard X-rays. The variability within the UV/optical bands is also strongly correlated, with the UV appearing to lead the optical by ∼0.5-1 days. This combination of 3 day lags between the X-rays and UV and 1 day lags within the UV/optical appears to rule out the "lamp-post" reprocessing model in which a hot, X-ray emitting corona directly illuminates the accretion disk, which then reprocesses the energy in the UV/optical. Instead, these results appear consistent with the Gardner & Done picture in which two separate reprocessings occur: first, emission from the corona illuminates an extreme-UV-emitting toroidal component that shields the disk from the corona; this then heats the extreme-UV component, which illuminates the disk and drives its variability.
Understanding how super-massive black holes form and grow in the early Universe has become a major challenge
since it was discovered that luminous quasars existed only 700 million years after the Big ...Bang
. Simulations indicate an evolutionary sequence of dust-reddened quasars emerging from heavily dust-obscured starbursts that then transition to unobscured luminous quasars by expelling gas and dust
. Although the last phase has been identified out to a redshift of 7.6 (ref.
), a transitioning quasar has not been found at similar redshifts owing to their faintness at optical and near-infrared wavelengths. Here we report observations of an ultraviolet compact object, GNz7q, associated with a dust-enshrouded starburst at a redshift of 7.1899 ± 0.0005. The host galaxy is more luminous in dust emission than any other known object at this epoch, forming 1,600 solar masses of stars per year within a central radius of 480 parsec. A red point source in the far-ultraviolet is identified in deep, high-resolution imaging and slitless spectroscopy. GNz7q is extremely faint in X-rays, which indicates the emergence of a uniquely ultraviolet compact star-forming region or a Compton-thick super-Eddington black-hole accretion disk at the dusty starburst core. In the latter case, the observed properties are consistent with predictions from cosmological simulations
and suggest that GNz7q is an antecedent to unobscured luminous quasars at later epochs.