The proof of concept of a new device, capable of determining in a few seconds the energy of clinical proton beams by measuring the time of flight (ToF) of protons, is presented. The prototype ...consists of two thin ultra fast silicon detector (UFSD) pads, aligned along the beam direction in a telescope configuration and readout by a digitizer. The method developed for extracting the energy at the isocenter from the measured ToF, validated by Monte Carlo simulations, and the procedure used to calibrate the system are also presented and discussed in detail. The prototype was tested at the Centro Nazionale di Adroterapia Oncologica (CNAO, Pavia, Italy), at several beam energies, covering the entire clinical range, and using different distances between the sensors. The measured beam energies were benchmarked against the nominal CNAO energy values, obtained during the commissioning of the centre from the measured ranges in water. Deviations of few hundreds of keV have been achieved for all considered proton beam energies for distances between the two sensors larger than 60 cm, indicating a sensitivity to the corresponding beam range in water smaller than the clinical tolerance of 1 mm. Moreover, few seconds of irradiation were necessary to collect the required statistics. These preliminary results indicate that a telescope of UFSDs could achieve in a short time the accuracy required for the clinical application and therefore encourage further investigations towards the improvement and the optimization of the present prototype.
Fluence profiling at JSI TRIGA reactor irradiation facility Sola, V.; Mandić, I.; Ambrožič, K. ...
Nuclear instruments & methods in physics research. Section A, Accelerators, spectrometers, detectors and associated equipment,
June 2024, 2024-06-00, Letnik:
1063
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We present an analysis of the fluence profile at the JSI TRIGA neutron reactor facility in Ljubljana. For the study, multi-pad Low-Gain Avalanche Diodes (LGADs) are used. The deactivation of acceptor ...doping in the gain layer implant due to the irradiation, typical of LGAD devices, is exploited to map the fluence profile inside the irradiation channels. The amount of active doping of the LGAD gain layer is extracted via capacitance–voltage measurements for each pad before and after irradiation to a fluence of 1.5 × 1015neq/cm2, where neq stands for 1 MeV equivalent neutron count, providing a precise and prompt measurement of the fluence distribution over the LGAD sensor. Experimental results are compared to neutron fluence expectations calculated with Monte Carlo techniques.
A fast 144-channel proton counter prototype, designed for monitoring the fluence rate of clinical proton beams, is based on a thin Low Gain Avalanche Detector (LGAD), segmented into 146 strips ...(114 μm width, 26214 μm length, 180 μm pitch). The layout of the sensor was designed in the framework of the Modeling and Verification for Ion beam Treatment planning (MoVe-IT) project in collaboration with Fondazione Bruno Kessler (FBK, Trento, Italy) and fourteen wafers were produced and delivered by FBK in 2020. In this paper, we present the laboratory characterization of the sensors performed on the entire wafer at FBK, right after production, and at the University of Turin after cutting the sensors using a probe station connected with a power device analyzer for static electrical tests and an infrared picosecond laser to study the dynamic properties. In addition, one sensor was tested with the clinical proton beam at National Center for Oncological Hadrontherapy (CNAO, Pavia, Italy).
The results obtained from the test at FBK and UNITO facilities demonstrated that the cut did not affect the yield production. The static electrical tests proved that the MoVe-IT-2020 sensors production was of very high quality. The width of the inter-strip dead region measured was 80.8 μm. 22% larger than the distance of the gain layers, and has a small dependence on laser intensities. A preliminary beam test at CNAO showed good separation between signal and noise in the LGAD strip, which allows counting properly the protons by selecting the optimal signal threshold.
Monitoring of carbon ion therapeutic beams with thin silicon sensors Montalvan Olivares, D.M.; Marti Villarreal, O.A.; Abujami, M. ...
Nuclear instruments & methods in physics research. Section A, Accelerators, spectrometers, detectors and associated equipment,
June 2024, 2024-06-00, Letnik:
1063
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Single ion counting in particle therapy may lead to new beam monitoring systems, enabling innovative delivery strategies that are faster and more sensitive than those currently used in clinics. ...Previous studies carried out by the University and the National Institute of Nuclear Physics (INFN) of Turin have demonstrated the feasibility of using thin silicon detectors to count single protons in clinical beams. The aim of this work is to report the performance of a strip-segmented 60-μm thick silicon PIN sensor used for single carbon ion discrimination. All measurements were performed using the CNAO synchrotron at different beam energies covering the clinical energy range (115–399 MeV/u). Signals from the sensor strips were read using a custom amplifier board and sampled with a 5 GS/s digitizer. The carbon ion signals were analyzed in terms of amplitude, duration, and deposited charge at different sensor bias voltages.
The MIUR PRIN 4DInSiDe collaboration aims at developing the next generation of 4D (i.e., position and time) silicon detectors based on Low-Gain Avalanche Diodes (LGAD) that guarantee to operate ...efficiently in the future high-energy physics experiments. To this purpose, different areas of research have been identified, involving the development, design, fabrication and test of radiation-hard devices. This research has been enabled thanks to ad-hoc advanced TCAD modelling of LGAD devices, accounting for both technological issues as well as physical aspects, e.g. different avalanche generation models and combined surface and bulk radiation damage effects modelling. In this contribution, it is reviewed the progress and the relevant detector developments obtained during the research activities in the framework of the 4DInSiDe project.
•TCAD modelling for the design of radiation-hard LGAD sensors for 4D tracking.•Gain layer compensation, (p＋- and n＋-doping) to preserve the gain at high fluences.•New design approach to resistive read-out sensors: DC-coupled RSD.•DC-RSD employs a direct coupling of the resistive layer to the read-out pads.•DC-coupled low resistivity strips between read-out pads to improve the resolution.
A prototype of proton counter was developed by the University and the National Institute for Nuclear Physics of Torino to be used as online fluence beam monitor in particle therapy. The single ...particle identification approach aims at increasing the sensitivity and readout speed with respect to the state-of-the-art gas ionization chambers. The sensitive area is 2,7 x 2,7 cm^2 to cover the clinical beam cross section characterized by a full width at half maximum of about 1 cm at the isocenter. The sensor is a thin Low Gain Avalanche Diode segmented in 146 strips with 180 micrometer pitch and with 50 micrometer active thickness, designed and produced by the Fondazione Bruno Kessler (Trento, Italy). The frontend readout to identify the single proton signal provided by each strip is based on a 24channel custom ASICs, named ABACUS, optimized to discriminate the signal pulses in a wide charge range (3-150 fC) with a maximum dead-time of 10 ns. With these specifications, at the maximum fluence rate of 10^8 p/(cm^2s) in the clinical energy range (60-230 MeV) and considering the silicon strips described above, a maximum pileup counting inefficiency less than 1 percent is achieved. A frontend board housing 6 ABACUS chips to readout the 146 strips was developed, the digital outputs being sent to 3 FPGAs (Kintex7) for the counting. A LabVIEW program implements the interface with the FPGAs, displays online the counting rate from each strip and stores the data for offline analysis.
The University of Torino (UniTO) and the National Institute for Nuclear Physics (INFN-TO) are investigating the use of Ultra Fast Silicon Detectors (UFSD) for beam monitoring in radiobiological ...experiments with therapeutic proton beams. The single particle identification approach of solid state detectors aims at increasing the sensitivity and reducing the response time of the conventional monitoring devices, based on gas detectors. Two prototype systems are being developed to count the number of beam particles and to measure the beam energy with time-of-flight (ToF) techniques. The clinically driven precision (< 1%) in the number of particles delivered and the uncertainty < 1 mm in the depth of penetration (range) in radiobiological experiments (up to 108 protons/s fluxes) are the goals to be pursued. The future translation into clinics would allow the implementation of faster and more accurate treatment modalities, nowadays prevented by the limits of state-of-the-art beam monitors. The experimental results performed with clinical proton beams at CNAO (Centro Nazionale di Adroterapia Oncologica, Pavia) and CPT (Centro di Protonterapia, Trento) showed a counting inefficiency <2% up to 100 MHz/cm2, and a deviation of few hundreds of keV of measured beam energies with respect to nominal ones. The progresses of the project are reported.
Fast procedures for the beam quality assessment and for the monitoring of beam energy modulations during the irradiation are among the most urgent improvements in particle therapy. Indeed, the online ...measurement of the particle beam energy could allow assessing the range of penetration during treatments, encouraging the development of new dose delivery techniques for moving targets. Towards this end, the proof of concept of a new device, able to measure in a few seconds the energy of clinical proton beams (from 60 to 230 MeV) from the Time of Flight (ToF) of protons, is presented. The prototype consists of two Ultra Fast Silicon Detector (UFSD) pads, featuring an active thickness of 80 um and a sensitive area of 3 x 3 mm2, aligned along the beam direction in a telescope configuration, connected to a broadband amplifier and readout by a digitizer. Measurements were performed at the Centro Nazionale di Adroterapia Oncologica (CNAO, Pavia, Italy), at five different clinical beam energies and four distances between the sensors (from 7 to 97 cm) for each energy. In order to derive the beam energy from the measured average ToF, several systematic effects were considered, Monte Carlo simulations were developed to validate the method and a global fit approach was adopted to calibrate the system. The results were benchmarked against the energy values obtained from the water equivalent depths provided by CNAO. Deviations of few hundreds of keV have been achieved for all considered proton beam energies for both 67 and 97 cm distances between the sensors and few seconds of irradiation were necessary to collect the required statistics. These preliminary results indicate that a telescope of UFSDs could achieve in a few seconds the accuracy required for the clinical application and therefore encourage further investigations towards the improvement and the optimization of the present prototype.
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