This study aimed to investigate the level of exposure of eye lenses in
orthopedic surgeons performing routine clinical work and to determine
future monitoring practice, as Serbian radiation ...protection law still
employs higher limits. The dose was measured monthly in terms of H (0.03)
with three different dosimeters placed on a 3-D-printed headband, worn on a
forehead by three orthopedic surgeons, during all procedures involving
fluoroscopy. The mean dose for the left and right eye was 271 ? 109 ?Sv and
269 ? 101 ?Sv, respectively, with no significant difference (p-value
0.977) between the left and right eye observed. Considering the highest
recorded monthly value, the annual dose is expected to be 4.85 mSv without
protective items, well below the new ICRP limit of 20 mSv. There was no
observed correlation between eye lens dose and both fluoroscopy time and
exposure parameters. Considering the cumulative impact of dose and the
evidence pointing to an elevated incidence of lenticular opacities for
cumulative doses exceeding 10 mSv, it is advisable to institute ongoing
monitoring, especially when new surgeons incorporate image-guided
procedures or when novel techniques are introduced into surgical practice.
MEEREB is an informal network of rabies experts from the Middle East, Eastern Europe and Central Asia, seeking to eliminate rabies from the region. They met for the second time to review the current ...rabies situation, both globally and in their respective countries, highlighting current rabies control problems and potential solutions. Success stories in Latin America, in Western Europe, in some Asian countries, as well as in Croatia and Serbia prove that elimination of human rabies is achievable in the MEEREB region. It requires political willingness and cooperation of all stakeholders, including Ministries of Health and of Agriculture; adequate management of animal bites through post‐exposure prophylaxis; pre‐exposure prophylaxis for populations at high risk of rabies exposure, animal vaccination and humane control of stray dog populations. MEEREB members called for a regional initiative for rabies elimination in Eastern Europe and the Middle East. They are confident that the elimination of human rabies of canine origin can be achieved in the region through adopting a One Health approach, and that campaigns for rabies elimination will have significant benefit for public health, including strengthening the structure for control of other zoonoses.
Abstract MEEREB is an inter-regional network of countries from North Africa, Europe, the Middle East and Central Asia that work together with the aim of improving rabies control and prevention at ...local, regional and global level. MEEREB members met for the third time in 2015 in France (Lyon) to review the current rabies situation within the network and to discuss the way forward the prospect of a One Health approach against rabies. Dogs were the main vector of transmission in all MEEREB countries except for Croatia and Serbia where foxes represented the primary source. The number of rabies animal cases reported in 2014 varied substantially between countries with Ukraine reporting the highest number of animal cases. Human cases still occur in North Africa and all Middle East and Eurasian countries while no cases of human rabies were reported in Croatia, Serbia and Romania, although cases of rabies were identified in both dogs and foxes in 2014. Participants concluded that MEEREB can act as a think-tank where countries can share data, information, experiences and best practices to jointly address challenges in rabies control and prevention. They called for elimination of dog-transmitted rabies through vaccine and rabies immunoglobulin stockpiles and implementation of a One Health approach to achieve rabies’s eradication.
In a prospective randomized trial in patients undergoing major abdominal surgery, the impact of a new enteral formula supplemented with arginine, ω-3 fatty acids, and nucleotides (A,
n = 14) on ...immunological parameters was compared with a standard enteral formula (B,
n = 14) and a low calorie/low fat intravenous solution (C,
n = 13). Four days postoperatively, a statistically significant decrease in total leukocyte count (A, 9.0 ± 2.9; B, 8.0 ± 2.4; C, 11.1 ± 3.5 × 10
6 cells/mL; A versus C, B versus C;
p < 0.05), higher percentage of lymphocytes (A, 14.3 ± 4.9; C, 8.2 ± 6.1;
p < 0.05), and decreased median CRP levels (A, 80.4 69.9; B, 70 74; C, 88.5 142 in mg/L; A versus C,
p < 0.05; B versus C;
p < 0.05) were observed in the enteral nutrition groups. The expression of activated surface antigen HLA-DR was diminished on CD14
+ cells over 4 d (A, 58.2 39.2; B, 52.2 36.2; C, 76.6 25.2 in %; A versus C,
p < 0.05; B versus C,
p < 0.05) and 8–10 d (A, 37.9 31.4; C, 58.5 37.6;
p < 0.05) postoperatively. Significantly enhanced median phagocytic activity of CD14
+ monocytes and granulocytes was observed in group C 8–10 days postoperatively (A, 83.3 11.8; B, 71.6 34.1; C, 87.4 10.8; A versus B, B versus C,
p < 0.05; and A, 75.7 10.0; B, 69.0 37.8; C, 80.0 10.1 in %, B versus C,
p < 0.05, respectively). Postoperative hospital and intensive care unit stay was similar among the three groups; however, infectious complications were less frequent in group A (A versus C,
p = 0.15). Thus, a modified enteral nutritional support and supplementation may influence the immune competence toward a more efficient defense response.
Summary
This longitudinal study of travellers to Africa taking mefloquine (MQ) chemoprophylaxis aimed to quantify and assess non‐serious adverse events (AE) occurring during short‐term prophylaxis ...and relate these to concentrations of racemic MQ, its enantiomers and metabolite. A total of 420 volunteers (52% F) participated. AEs with some impact on activities were reported by 11.2% of participants including 7.9% of neurological/psychiatric symptoms. Women were more likely to report AEs (P=0.02). The standardized questionnaires used showed more pathological indicators in travellers who reported subjective AE with significantly more dizziness, distress, sleep disturbances and a high total mood disturbance (TMD) in the AE group. There was, however, no significant performance deficit in computerized psychomotor tests in those experiencing AE. Furthermore, no significant differences were observed in enantiomer ratios, metabolite concentrations, or racemic MQ levels in participants with or without AEs suggesting that these factors are not the main predictors of mefloquine intolerability.
Symmetry 2023, 15(10), 1948 In this paper we present two machine learning algorithms to identify $D$
mesons produced in a color singlet state from radiative $W$ boson decays at the
LHC. The combined ...network algorithm is able to identify $D$ mesons via its
hadronic decays with an efficiency of 47% while suppressing a background of
quark and gluon jets by a factor of 100. Using the developed algorithm, we
perform a prospective study for the measurement of $\mathcal{B}(W\to
D_{s}\gamma)$.
In this paper we present two machine learning algorithms to identify \(D\) mesons produced in a color singlet state from radiative \(W\) boson decays at the LHC. The combined network algorithm is ...able to identify \(D\) mesons via its hadronic decays with an efficiency of 47% while suppressing a background of quark and gluon jets by a factor of 100. Using the developed algorithm, we perform a prospective study for the measurement of \(\mathcal{B}(W\to D_{s}\gamma)\).
A search for the Standard Model Higgs boson has been performed in the H->WW->lnujj channel using 4.7 fb^-1 of pp collision data recorded at a centre-of-mass energy of sqrt(s) = 7 TeV with the ATLAS ...detector at the Large Hadron Collider. Higgs boson candidates produced in association with zero, one or two jets are included in the analysis to maximize the acceptance for both gluon fusion and weak boson fusion Higgs boson production processes. No significant excess of events is observed over the expected background and limits on the Higgs boson production cross section are derived for a Higgs boson mass in the range 300 GeV < mH < 600 GeV. The best sensitivity is reached for mH = 400 GeV, where the observed (expected) 95% confidence level upper bound on the cross section for H->WW produced in association with zero or one jet is 2.2 pb (1.9 pb), corresponding to 1.9 (1.6) times the Standard Model prediction. In the Higgs boson plus two jets channel, which is more sensitive to the weak boson fusion process, the observed (expected) 95% confidence level upper bound on the cross section for H->WW production with mH = 400 GeV is 0.7 pb (0.6 pb), corresponding to 7.9 (6.5) times the Standard Model prediction.
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