While swimming represents a popular recreational activity, the immersion of the human body into the water requires a complex physiologic adaption of the whole cardiopulmonary and circulatory system. ...While this sport is regarded as beneficial, especially in cardiovascular patients, current guidelines hypothesized a possible hazardous effect of swimming and especially diving in patients with univentricular hearts after Fontan palliation. Yet, actual data to underline or contradict these assumptions are lacking. Therefore, this study aimed to conduct a first feasibility study for the evaluation of these effects on Fontan physiology and elucidate the gap of evidence currently preventing patients after Fontan palliation from being restricted from swimming or diving on doctoral advice. Patients recruited from the Heart Center Leipzig, Department of pediatric cardiology, underwent spiroergometry treadmill testing followed by a spiroergometry swimming stress test in a counter current pool. Physiologic data were recorded. A short apnea diving test was performed. The current study found similar physiologic reactions comparing treadmill and swimming exercise stress testing. Heart rate response and oxygen uptake were comparable on land and in the water. This study presents the first-in-man data on swimming and diving in Fontan patients. In this small study cohort of three Fontan patients, there were no adverse events triggered by swimming and breath-hold diving seen. Basically, the physiologic response to exercise was comparable on land and in the water.
Swimming and diving are popular recreational activities. As congenital heart disease, especially patients with univentricular hearts after Fontan palliation are thought to have reduced physiologic ...capacities for compensation of submersion-associated physiologic demands, current guidelines put restraints on this group of patients. Although these restrictions on doctoral advice place a significant burden on affected patients, it is especially interesting that these guideline recommendations are merely based on physiologic assumptions, i.e., expert consensus. A recent study by Paech et al. presented the first in vivo data on the effects of immersion in Fontan patients, stating no major adverse events in their study group as well as comparable physiologic adaption as reported in the literature for healthy people. Yet, submersion was not reflected in this study, and the current study therefore aimed to conduct a first study for the evaluation of the effects of submersion and apnea diving in Fontan patients. A control group of healthy adults as well as patients recruited from the Heart Center Leipzig, Department of pediatric cardiology underwent a standardized diving protocol including a static as well as dynamic apnea phase. Physiologic data were recorded. This study presents the first structured data on diving physiology in Fontan patients compared to healthy probands. There were no adverse events. The physiologic response to diving seems to be comparable between healthy probands and Fontan patients. Although, healthy probands did reach a much better performance, the basic mechanisms of physiologic adaption seem comparable.
Swimming and diving are popular recreational activities, representing an effective option in maintaining and improving cardiovascular fitness in healthy people. To date, only little is known about ...the cardiovascular adaption to submersion in children. This study was conducted to improve an understanding thereof. We used a stepwise apnea protocol with apnea at rest, apnea with facial immersion, and at last apnea during whole body submersion. Continuous measurement of heart rate, oxygen saturation, and peripheral resistance index was done. Physiologic data and analysis of influencing factors on heart rate, oxygen saturation, and peripheral vascular tone response are reported. The current study presents the first data of physiologic diving response in children. Data showed that facial or whole body submersion leads to a major drop in heart rate, and increase of peripheral resistance, while the oxygen saturation seems to be unaffected by static apnea in most children, with apnea times of up to 75 s without change in oxygen saturation.
Employing the Bonn–Gatchina partial wave analysis framework (PWA), we have analyzed HADES data of the reaction p(3.5 GeV)+p→pK+Λ. This reaction might contain information about the kaonic cluster ...“ppK−” (with quantum numbers JP=0− and total isospin I=1/2) via its decay into pΛ. Due to interference effects in our coherent description of the data, a hypothetical K‾NN (or, specifically “ppK−”) cluster signal need not necessarily show up as a pronounced feature (e.g. a peak) in an invariant mass spectrum like pΛ. Our PWA analysis includes a variety of resonant and non-resonant intermediate states and delivers a good description of our data (various angular distributions and two-hadron invariant mass spectra) without a contribution of a K‾NN cluster. At a confidence level of CLs=95% such a cluster cannot contribute more than 2–12% to the total cross section with a pK+Λ final state, which translates into a production cross-section between 0.7 μb and 4.2 μb, respectively. The range of the upper limit depends on the assumed cluster mass, width and production process.
.
The HADES data from p + Nb collisions at a center-of-mass energy of
GeV are analyzed employing a statistical hadronization model. The model can successfully describe the production yields of the ...identified hadrons
,
,
,
K
0
s
,
with parameters
MeV and
MeV, which fit well into the chemical freeze-out systematics found in heavy-ion collisions. In addition, we reanalyze our previous HADES data from Ar + KCl collisions at
GeV with an updated version of the model. We address equilibration in heavy-ion collisions by testing two aspects: the description of yields and the regularity of freeze-out parameters from a statistical model fit as a function of colliding energy and system size. Despite its success, the model fails to describe the observed
yields in both, p + Nb and Ar + KCl . Special emphasis is put on feed-down contributions from higher-lying resonance states as a possible explanation for the observed excess.
High-rate timing resistive plate chambers with ceramic electrodes Laso Garcia, A.; Kotte, R.; Naumann, L. ...
Nuclear instruments & methods in physics research. Section A, Accelerators, spectrometers, detectors and associated equipment,
05/2016, Letnik:
818
Journal Article
Recenzirano
We describe recent advances in developing radiation-hard ceramic resistive plate chambers (CRPCs) with Si3N4/SiC composites. Bulk resistivity measurements for this material for different ...manufacturing processes are reported. The results show that the bulk resistivity ρ can vary between 107and1013Ωcm. The varistor type behaviour of the material is analysed. A comparison with other materials used in timing RPCs is given. We describe the assembly and tests of CRPC prototypes in electron and proton beams. For a prototype with ρ~5×109Ωcm, the efficiency of the detectors is 95% at a flux of 2×105cm−2s−1. The time resolution at the same flux is about 120ps. A prototype with ρ~2×1010Ωcm shows an efficiency of about 85% up to fluxes of 5×104cm−2s−1 with a time resolution better than 80ps. The results are compared with RPC models.
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