Most millimeter wave (mmWave) channel measurements are conducted with different configurations, which may have large impacts on propagation channel characteristics. In addition, the comparison of ...different mmWave bands is scarce. Moreover, mmWave massive multiple-input multiple-output (MIMO) channel measurements are absent, and new propagation properties caused by large antenna arrays have rarely been studied yet. In this paper, we carry out mmWave massive MIMO channel measurements at 11-, 16-, 28-, and 38-GHz bands in indoor environments. The space-alternating generalized expectation-maximization algorithm is applied to process the measurement data. Important statistical properties, such as average power delay profile, power azimuth profile, power elevation profile, root mean square delay spread, azimuth angular spread, elevation angular spread, and their cumulative distribution functions and correlation properties, are obtained and compared for different bands. New massive MIMO propagation properties, such as spherical wavefront, cluster birth-death, and non-stationarity over the antenna array, are validated for the four mmWave bands by investigating the variations of channel parameters. Two channel models are used to verify the measurements. The results indicate that massive MIMO effects should be fully characterized for mmWave massive MIMO systems.
In this paper, a generic and adaptive geometrybased stochastic model (GBSM) is proposed for non-isotropic multiple-input multiple-output (MIMO) mobile-to-mobile (M2M) Ricean fading channels. The ...proposed model employs a combined two-ring model and ellipse model, where the received signal is constructed as a sum of the line-of-sight, single-, and doublebounced rays with different energies. This makes the model sufficiently generic and adaptable to a variety of M2M scenarios (macro-, micro-, and pico-cells). More importantly, our model is the first GBSM that has the ability to study the impact of the vehicular traffic density on channel characteristics. From the proposed model, the space-time-frequency correlation function and the corresponding space-Doppler-frequency power spectral density (PSD) of any two sub-channels are derived for a non-isotropic scattering environment. Based on the detailed investigation of correlations and PSDs, some interesting observations and useful conclusions are obtained. These observations and conclusions can be considered as a guidance for setting important parameters of our model appropriately and building up more purposeful measurement campaigns in the future. Finally, close agreement is achieved between the theoretical results and measured data, demonstrating the utility of the proposed model.
The plastid is a semiautonomous organelle with its own genome. Plastid genomes have been widely used as models for studying phylogeny, speciation and adaptive evolution. However, most studies focus ...on comparisons of plastid genome evolution at high taxonomic levels, and comparative studies of the process of plastome evolution at the infrageneric or intraspecific level remain elusive. Holcoglossum is a small genus of Orchidaceae, consisting of approximately 20 species of recent radiation. This made it an ideal group to explore the plastome mutation mode at the infrageneric or intraspecific level.
In this paper, we reported 15 complete plastid genomes from 12 species of Holcoglossum and 1 species of Vanda. The plastid genomes of Holcoglossum have a total length range between 145 kb and 148 kb, encoding a set of 102 genes. The whole set of ndh-gene families in Holcoglossum have been truncated or pseudogenized. Hairpin inversion in the coding region of the plastid gene ycf2 has been found.
Using a comprehensive comparative plastome analysis, we found that all the indels between different individuals of the same species resulted from the copy number variation of the short repeat sequence, which may be caused by replication slippage. Annotation of tandem repeats shows that the variation introduced by tandem repeats is widespread in plastid genomes. The hairpin inversion found in the plastid gene ycf2 occurred randomly in the Orchidaceae.
The recent development of high-speed trains (HSTs) as an emerging high mobility transportation system, and the growing demands of broadband services for HST users, introduce new challenges to ...wireless communication systems for HSTs. Accurate and efficient channel models considering both large-scale and non-stationary small-scale fading characteristics are crucial for the design, performance evaluation, and parameter optimization of HST wireless communication systems. However, the characteristics of the underlying HST channels have not yet been sufficiently investigated. This paper first provides a comprehensive review of the measurement campaigns conducted in different HST scenarios and then addresses the recent advances in HST channel models. Finally, key challenges of HST channel measurements and models are discussed and several research directions in this area are outlined.
A high‐performance nonprecious‐metal oxygen‐reduction electrocatalyst is prepared via in situ growth of bimetallic zeolitic imidazolate frameworks on multiwalled carbon nanotubes (CNTs) followed by ...adsorption of furfuryl alcohol and pyrolysis. The networking boosts the conductivity and performance in a polymer electrolyte membrane fuel cell, yielding a maximal power density of 820 mW cm−2.
With the increasing problem of antimicrobial drug resistance, the search for new antimicrobial agents has become a crucial task in the field of medicine. Antimicrobial peptides, as a class of ...naturally occurring antimicrobial agents, possess broad-spectrum antimicrobial activity and lower risk of resistance development. However, traditional screening methods for antimicrobial peptides are inefficient, necessitating the development of an efficient screening model. In this study, we aimed to develop an ensemble learning model for the identification of antimicrobial peptides, named E-CLEAP, based on the Multilayer Perceptron Classifier (MLP Classifier). By considering multiple features, including amino acid composition (AAC) and pseudo amino acid composition (PseAAC) of antimicrobial peptides, we aimed to improve the accuracy and generalization ability of the identification process. To validate the superiority of our model, we employed five-fold cross-validation and compared it with other commonly used methods for antimicrobial peptide identification. In the experimental results on an independent test set, E-CLEAP achieved accuracies of 97.33% and 84% for the AAC and PseAAC features, respectively. The results demonstrated that our model outperformed other methods in all evaluation metrics. The findings of this study highlight the potential of the E-CLEAP model in enhancing the efficiency and accuracy of antimicrobial peptide screening, which holds significant implications for drug development, disease treatment, and biotechnology advancement. Future research can further optimize the model by incorporating additional features and information, as well as validating its reliability on larger datasets and in real-world environments. The source code and all datasets are publicly available at https://github.com/Wangsicheng52/E-CLEAP.
Alzheimer’s disease (AD) is a most serious age-related neurodegenerative disorder accompanied with significant memory impairments in this world. Recently, microRNAs (miRNAs) have been reported to be ...invlolved in the pathophysiology of AD. Previous studies have shown that miRNA-206 (miR-206) is implicated in the pathogenesis of AD via suppressing the expression of brain-derived neurotrophic factor (BDNF) in the brain. Here, we examined the miR-206-3p and miR-206-5p expression in the hippocampus and cortex of Abeta precursor protein (APP)/presenilin-1 (PS1) transgenic mice treated with donepezil, a drug approved for treating AD in clinic. We found that the expression of miR-206-3p was significantly up-regulated in the hippocampus and cortex of APP/PS1 mice, while donepezil administration significantly reversed this dysfunction. In addition, enhancing the miR-206-3p level by the usage of AgomiR-206-3p significantly attenuated the anti-dementia effects of donepezil in APP/PS1 mice. Together, these results suggested that miR-206-3p is involved in the anti-dementia effects of donepezil, and could be a novel pharmacological target for treating AD.
While the term interactive marketing often has diverse definitions and usages among marketing professionals and practitioners, it is defined here as the bi-directional value creation and ...mutual-influence marketing process through active customer connection, engagement, participation and interaction. ...a definition characterizes interactive marketing in terms of the following aspects, namely, first, it is a two-way communication with mutual influences in social and business ecosystems; second, it focuses on customer responsiveness and often proactive behaviors in value creation and exchange; and third, its interactivity involves customer participation and engagement in controlling and modifying the environment in real-time (Steuer, 1992). The growth of digital platforms has displaced traditional intermedia not only by creating a new type of superpower of omnichannel marketplace spanning online and offline retailers but also changed business models from a linear supply chain pipeline to a complex network of producers and users in an interconnected ecosystem (Parker, VA Alstyne and Choudary, 2016). ...participants can swap their roles from hosts to customers on Airbnb, from drivers to riders on Uber and Didi, from media content creators to audience on Youtube and Wikipedia.
For future networks i.e., the fifth generation (5G) wireless networks and beyond, millimeter-wave (mmWave) communication with large available unlicensed spectrum is a promising technology that ...enables gigabit multimedia applications. Thanks to the short wavelength of mmWave radio, massive antenna arrays can be packed into the limited dimensions of mmWave transceivers. Therefore, with directional beamforming, both mmWave transmitters (MTXs) and mmWave receivers (MRXs) are capable of supporting multiple beams in 5G networks. However, for the transmission between an MTX and an MRX, most works have only considered a single beam, which means that they do not make full potential use of mmWave. Furthermore, the connectivity of single beam transmission can easily be blocked. In this context, we propose a single-user (SU) multi-beam concurrent transmission scheme for future mmWave networks with multiple reflected paths. Based on spatial spectrum reuse, the scheme can be described as a multiple-input multiple-output (MIMO) technique in beamspace (i.e., in the beam-number domain). Moreover, this paper investigates the challenges and potential solutions for implementing this scheme, including multi-beam selection, cooperative beam tracking, multi-beam power allocation, and synchronization. The theoretical and numerical results show that the proposed beamspace SU-MIMO can largely improve the achievable rate of the transmission between an MTX and an MRX and, meanwhile, can maintain the connectivity.
With the massive multi-input multi-output (MIMO) antennas technology adopted for the fifth generation (5G) wireless communication systems, a large number of radio frequency (RF) chains have to be ...employed for RF circuits. However, a large number of RF chains not only increase the cost of RF circuits but also consume additional energy in 5G wireless communication systems. In this paper, we investigate energy and cost efficiency optimization solutions for 5G wireless communication systems with a large number of antennas and RF chains. An energy efficiency optimization problem is formulated for 5G wireless communication systems using massive MIMO antennas and millimeter wave technology. Considering the nonconcave feature of the objective function, a suboptimal iterative algorithm, i.e., the energy efficient hybrid precoding (EEHP) algorithm is developed for maximizing the energy efficiency of 5G wireless communication systems. To reduce the cost of RF circuits, the energy efficient hybrid precoding with the minimum number of RF chains (EEHP-MRFC) algorithm is also proposed. Moreover, the critical number of antennas searching (CNAS) and user equipment number optimization (UENO) algorithms are further developed to optimize the energy efficiency of 5G wireless communication systems by the number of transmit antennas and UEs. Compared with the maximum energy efficiency of conventional zero-forcing (ZF) precoding algorithm, numerical results indicate that the maximum energy efficiency of the proposed EEHP and EEHP-MRFC algorithms are improved by 220% and 171%, respectively.