For a distorted black hole (BH), its ringdown waveform is a superposition of quasi-normal modes (QNMs). In general relativity (GR), the lower order QNM frequencies and damping rates can be well ...approximated by a polynomial of BH’s dimensionless spin and overall scaled by BH’s mass. That is to say, we can test the no-hair theorem of BH in GR model-independently by allowing not only an overall fractional deviation (as M. Isi et al. did) but also a set of fractional deviation for every coefficient. In the paper, we will apply the latter method to retest the no-hair theorem with GW150914 and probe hairs’ behaviors if hairs exist. Eventually, we find the data favors GR.
In the context of intelligent manufacturing, machinery and equipment in the industrial manufacturing process form the “industrial Internet of Things.” In this process of interlocking production, the ...requirements for sensor data delay typically reach the millisecond level. Once the data is delayed, the equipment will be shut down, which will make the production difficult or dangerous. In the context of intelligent manufacturing, local computers have been unable to complete calculations and decisions quickly and on time for the huge computing demands. Therefore, the cloud computing migration mode needs to be introduced, but cloud computing migration will cause additional delays. Based on the above problems, this paper designs a cloud cooperative migration strategy based on the information exchange structure of the industrial Internet of Things and the delay mechanism caused by the migration. The feasibility of selecting the optimal migration strategy based on task partitioning is verified by simulation.
We numerically integrate the Einstein’s equations for a spatially flat Friedmann–Lemaire–Robertson–Walker (FLRW) background spacetime with a spatial curvature perturbation and evolving primordial ...tensor perturbations using the Einstein Toolkit. We find that although the primordial tensor perturbation does not play an important role in the evolution of the overdensity produced by the scalar perturbation, there is an obvious imprint left by the primordial tensor perturbation on the distribution of the fractional density perturbation in the nonlinear region. This imprint may be a possible probe of a gravitational waves background in the future.
The fabrication of chiral molecules into macroscopic systems has many valuable applications, especially in the fields of optical displays, data encryption, information storage, and so on. Here, we ...design and prepare a serious of supramolecular glasses (SGs) based on Zn-L-Histidine complexes, via an evaporation-induced self-assembly (EISA) strategy. Metal-ligand interactions between the zinc(II) ion and chiral L-Histidine endow the SGs with interesting circularly polarized afterglow (CPA). Multicolored CPA emissions from blue to red with dissymmetry factor as high as 9.5 × 10
and excited-state lifetime up to 356.7 ms are achieved under ambient conditions. Therefore, this work not only communicates the bulk SGs with wide-tunable afterglow and large circular polarization, but also provides an EISA method for the macroscopic self-assembly of chiral metal-organic hybrids toward photonic applications.
Besides genome editing, CRISPR-Cas12a has recently been used for DNA detection applications with attomolar sensitivity but, to our knowledge, it has not been used for the detection of small ...molecules. Bacterial allosteric transcription factors (aTFs) have evolved to sense and respond sensitively to a variety of small molecules to benefit bacterial survival. By combining the single-stranded DNA cleavage ability of CRISPR-Cas12a and the competitive binding activities of aTFs for small molecules and double-stranded DNA, here we develop a simple, supersensitive, fast and high-throughput platform for the detection of small molecules, designated CaT-SMelor (CRISPR-Cas12a- and aTF-mediated small molecule detector). CaT-SMelor is successfully evaluated by detecting nanomolar levels of various small molecules, including uric acid and p-hydroxybenzoic acid among their structurally similar analogues. We also demonstrate that our CaT-SMelor directly measured the uric acid concentration in clinical human blood samples, indicating a great potential of CaT-SMelor in the detection of small molecules.
The Multiple Sequentially Markovian Coalescent (MSMC) is a population genetic method and software for inferring demographic history and population structure through time from genome sequences. Here ...we describe the main program MSMC and its successor MSMC2. We go through all the necessary steps of processing genomic data from BAM files all the way to generating plots of inferred population size and separation histories. Some background on the methodology itself is provided, as well as bash scripts and python source code to run the necessary programs. The reader is also referred to community resources such as a mailing list and github repositories for further advice.
We simulate the evolution of a dust universe from
z
=
1089
to
z
=
0
by numerically integrating the Einstein’s equation for a spatially flat Friedmann–Lemaire–Robertson–Walker (FLRW) background ...spacetime with scalar perturbations which are derived from the matter power spectrum produced with the Code for Anisotropies in the Microwave Background (CAMB). To investigate the effects of primordial gravitational waves (GWs) on the inhomogeneity of the universe, we add an additional decaying, divergenceless and traceless primordial tensor perturbation with its initial amplitude being
3
×
10
-
4
to the above metric. We find that this primordial tensor perturbation suppresses the matter power spectrum by about
0.01
%
at
z
=
0
for modes with wave number similar to its. This suppression may be a possible probe of a GWs background in the future.
Fault diagnosis and prognosis in mechanical systems have been researched and developed in the last few decades at a very rapid rate. However, owing to the high complexity of machine centers, research ...on improving the accuracy and reliability of fault diagnosis and prognosis via data mining remains a prominent issue in this field. This study investigates fault diagnosis and prognosis in machine centers based on data mining approaches to formulate a systematic approach and obtain knowledge for predictive maintenance in Industry 4.0 era. We introduce a system framework based on Industry 4.0 concepts, which includes the process of fault analysis and treatment for predictive maintenance in machine centers. The framework includes five modules: sensor selection and data acquisition module, data preprocessing module, data mining module, decision support module, and maintenance implementation module. Furthermore, a case study is presented to illustrate the application of the data mining methods for fault diagnosis and prognosis in machine centers as an Industry 4.0 scenario.
Corin, a transmembrane serine protease that can cleave pro‐atrial natriuretic peptide (Pro‐ANP) into smaller bioactive molecule atrial natriuretic peptide, has been shown to be involved in the ...pathophysiology of hypertension, cardiac hypertrophy. We sought to examine the associations of corin genetic variations with salt sensitivity, blood pressure (BP) changes and hypertension incidence. We studied participants of the original Baoji Salt‐Sensitive cohort, recruited from 124 families from seven Chinese villages in 2004 who sequentially received a usual baseline salt diet, a 7‐day low salt diet (3 g/day) and a 7‐day high salt diet (18 g/day), respectively. They were followed up for 8 years (in 2009, 2012) to evaluate the development of hypertension. Corin SNP rs3749584 was significantly associated with diastolic BP (DBP) and mean arterial pressure (MAP) response to low‐salt diet, while rs4695253, rs17654278 were associated with pulse pressure (PP) response to low‐salt diet. SNPs rs4695253, rs12509275, rs2351783, rs2271036, rs2271037 were significantly associated with systolic BP (SBP), DBP, and MAP responses to high‐salt diet. In addition, SNPs rs12641823, rs6834933, rs2271036, and rs22710367 were significantly associated with the longitudinal changes in SBP, DBP, MAP, or PP over 8 years of follow‐up. SNP rs73814824 was significantly associated with the incidence of hypertension over 8 years. Gene‐based analysis showed that corin gene was significantly associated with longitudinal BP changes and hypertension incidence after 8‐year follow‐up. This study suggests that corin may play a role in salt sensitivity, BP progression, and development of hypertension.
The government and the market are the two main means for resource allocation, and both play important roles in economic development and environmental protection. Based on the theoretical mechanism ...analysis, this study empirically investigated the relationship between government intervention, market development, and China's provincial pollution emission efficiency by using the static panel OLS, system generalized method of moments (SYS-GMM), and panel threshold effect model during the period 2000–2017. The results show that the impact of government intervention on China's provincial pollution emission efficiency shows a non-linear U-shaped curve relationship, and there is a positive correlation between market development and provincial pollution emission efficiency in China. Government intervention and market development are complementary, rather than a substitute for each other, in promoting China's provincial pollution emission efficiency. When government intervention is set as the threshold variable, the impact of government intervention on China's provincial pollution emission efficiency shows the feature of “promotes first, then inhibits.” However, when market development is set as the threshold variable, government intervention is only conducive to the improvement of China's provincial pollution emission efficiency at a moderate marketization level. Lastly, some policy implications related to the government and the market in enhancing China's provincial pollution emission efficiency are presented.
Display omitted
•The relationship between government intervention, market development and pollution emission efficiency is investigated from both theoretical and empirical perspectives.•Government intervention and market development are complementary in promoting China’s provincial pollution emission efficiency.•Panel threshold effect model is employed to explore the joint impact of government intervention, market development on China’s provincial pollution emission efficiency.
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