Drawing from identity threat theory, this study aims to understand how and when employee voice can lead to abusive supervision. It proposes and examines a theoretical model in which employee voice is ...linked to abusive supervision through the mediating effect of leader identity threat.
We conducted a field study by collecting data from 93 supervisors and 533 subordinates in China at two different points in time. A structural equation model and Mplus software were used to examine the direct relationship between employee voice and abusive supervision, as well as the mediating effect of leader identity threat and the moderating effect of supervisor traditionality.
Our results showed that employee voice was positively related to leader identity threat and had an indirect effect on abusive supervision via leader identity threat. In addition, we found that supervisor traditionality moderated the relationship between employee voice and leader identity threat. Subordinates' voice increased perceptions of leader identity threat among supervisors with high traditionality, whereas supervisors with low traditionality did not make this association. Finally, the indirect effect of employee voice on abusive supervision via leader identity threat was moderated by supervisor traditionality.
First, this study broadens our understanding of the antecedents of abusive supervision by proposing that employee voice may induce abusive supervision. Second, it develops an identity threat perspective to explain why employee voice is positively related to abusive supervision. Finally, it enriches the research on implicit leadership theories by proposing that supervisors' cultural values can also influence supervisors' sense-making of subordinates' behaviors.
Ginseng, Panax ginseng (C. A. Mey.), is a well-known Chinese traditional medicine in the Far East and has gained popularity in the West during the last decade. There is extensive literature on the ...chemical constituents and bioactivities of ginseng. In this paper we compiled the chemical constituents isolated and detected from ginseng including polysaccharides, ginsenosides, peptides, polyacetylenic alcohols, fatty acids, etc. Meanwhile we summarized the biological activities of ginseng, which have been reported over the past few decades, including: anti-aging activity, anti-diabetic activity, immunoregulatory activity, anti-cancer activity, neuroregulation activity, wound and ulcer healing activity, etc. Nevertheless, further studies to exploit other kinds of constituents and new biological activities of ginseng are still necessary to facilitate research and development in the future.
The extrinsic diet and the intrinsic developmental programs are intertwined. Although extensive research has been conducted on how nutrition regulates development, whether and how developmental ...programs control the timing of nutritional responses remain barely known. Here, we report that a developmental timing regulator, BLMP-1/BLIMP1, governs the temporal response to dietary restriction (DR). At the end of larval development, BLMP-1 is induced and interacts with DR-activated PHA-4/FOXA, a key transcription factor responding to the reduced nutrition. By integrating temporal and nutritional signaling, the DR response regulates many development-related genes, including gska-3/GSK3β, through BLMP-1-PHA-4 at the onset of adulthood. Upon DR, a precocious activation of BLMP-1 in early larval stages impairs neuronal development through gska-3, whereas the increase of gska-3 by BLMP-1-PHA-4 at the last larval stage suppresses WNT signaling in adulthood for DR-induced longevity. Our findings reveal a temporal checkpoint of the DR response that protects larval development and promotes adult health.
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•gska-3 suppresses WNT signaling upon DR•The heterochronic gene BLMP-1 interacts with PHA-4 to time DR responses•BLMP-1-controlled timing protects larval development upon DR•BLMP-1-controlled timing promotes adult longevity upon DR
Hu et al. uncover how the developmental timing regulator BLMP-1/BLIMP1 governs the temporal response to dietary restriction (DR) by interacting with DR-activated PHA-4/FOXA. Their findings reveal a temporal checkpoint of the DR response crucial for protecting larval development and promoting adult health.
In the remote sensing field, deep learning-based methods have become mainstream for remote sensing image object detection in recent years. However, traditional methods, such as convolutional neural ...networks (CNNs), mainly ignore the dependencies between features, failing to capture the spatial relationships and relative positions of objects, which affects the detection performance of dense objects, especially small-size objects. To this end, a high-order feature association network (HOFA-Net) for dense object detection in remote sensing has been proposed to better capture the interdependencies between features of channel and spatial dimensions, yielding more distinguishable features. First, we employ CNNs to learn high-level but low-resolution features of objects. To capture feature interdependencies while retaining crucial information, we design a feature association module based on size adaptation nonlocal. This module partitions the low-resolution and high-level features into local regions and utilizes nonlocal residual connections to capture the local contextual information of objects. In addition, we introduce a high-order feature association (HFA) module designed to learn nonlinear feature correlations and interdependencies within the features. In addition, a covariance normalization acceleration strategy is introduced to accelerate computation. Experimental results on two public remote sensing datasets, including the DOTA dataset and the Tiny Person dataset, demonstrate the superiority and effectiveness of the proposed method through comparative experiments.
The study explored the potential protective impact of the probiotic fungus
in Fuzhuan brick tea on ulcerative colitis, along with the underlying mechanism. A spore suspension of
was administered to ...C57BL/6 mice to alleviate DSS-induced colitis. The findings indicated that administering
evidently enhanced the ultrastructure of colonic epithelium, showing characteristics such as enhanced TJ length, reduced microvilli damage, and enlarged intercellular space. After HLL supplementation, the activation of the liver inflammation pathway, including TLR4/NF-kB and NLRP3 inflammasome caused by DSS, was significantly suppressed, and bile acid metabolism, linking liver and gut, was enhanced, manifested by restoration of bile acid receptor (FXR, TGR5) level. The dysbiosis of the gut microbes in colitis mice was also restored by HLL intervention, characterized by the enrichment of beneficial bacteria (
,
,
, and
) and fungi (
,
,
,
, and
), which was closely associated with lipid metabolism and amino acid metabolism, and was negatively correlated with inflammatory gene expression. Hence, the recovery of gut microbial community structure, implicated deeply in the inflammatory index and metabolites profile, might play a crucial role in the therapeutic mechanism of HLL on colitis.
The activities and stabilities of Pt, Ni, Co, and Cu catalysts for H
2 production by aqueous-phase reforming of glycerol, as well as the effect of support on activity and stability, were studied ...using a fixed-bed flow reactor. Both of the fresh and spent catalysts were characterized by XRD, N
2 adsorption/desorption, TPO, H
2-TPR, and H
2 chemisorption. It was found that the activity of the metal catalysts increased in the order of Co, Ni, Cu and Pt. Additionally, Pt was highly stable, whereas Ni and Co showed significant deactivation with time on stream. It was also found that the activity of supported Pt catalysts was given as follows: SAPO-11
<
AC(active carbon)
<
HUSY
<
SiO
2
<
MgO
<
Al
2O
3. Moreover, basic support resulted in high activity and higher hydrogen molar concentration, whereas acidic support and neutral Al
2O
3 support tended to increase alkane formation. It was shown by XRD that Pt was caused to sinter on all of the supported Pt catalysts during the reaction. In addition, trace amount of carbon deposition was found on all of the supported Pt catalysts. However, no remarkable deactivation was observed over Pt/Al
2O
3, Pt/SiO
2, Pt/AC, and Pt/HUSY catalysts. Noteworthy was the investigation of the two zeolite-supported catalysts. However, low activities as well as the collapse of the support were obtained. In addition, little influence of the collapse of the support on the stability of Pt/HUSY was observed, whereas Pt/SAPO-11 exhibited remarkable deactivation.
A new photoelectrochemical (PEC) biosensor was developed by using carboxyl‐functionalized graphene and CdSe nanoparticles. This sensitive interface was then successfully applied to detection of ...thrombin based on the dual‐quenched effect of PEC nanoparticle, which relied on the electron transfer of a bipyridinium relay and energy transfer of AuNPs. After recognition with an aptamer, the PEC nanoparticle was removed and a signal‐on PEC biosensor was obtained. Moreover, the bio‐barcode technique used in the preparation of PEC nanoparticle could avoid cross‐reaction and enhances the sensitivity. Taking advantages of the various methods mentioned above, the sensitivity could be easily enhanced. In addition, in this work we also investigated graphene that was modified with different functional groups and AuNPs of different particle sizes. Under optimal conditions, a detection limit of 5.9×10−15 M was achieved. With its simplicity, selectivity, and sensitivity, this strategy shows great promise for the fabrication of highly efficient PEC biosensors.
PECking order! A new photoelectrochemical (PEC) biosensor was developed by using carboxyl‐functionalized graphene and CdSe nanoparticles (NPs). This sensitive interface was successfully applied to detection of thrombin based on the dual‐quenched effect of a PEC nanoparticle, which relied on the electron transfer of a bipyridinium relay and energy transfer of AuNPs (see figure). After recognition with an aptamer, the PEC nanoparticle was removed and a signal‐on PEC biosensor was obtained. (TEOA=triethanolamine.)
The cold atom gravimeter (CAG) has proven to be a powerful quantum sensor for the high-precision measurement of gravity field, which can work stably for a long time in the laboratory. However, most ...CAGs cannot operate in the field due to their complex structure, large volume and poor environmental adaptability. In this paper, a home-made, miniaturized CAG is developed and a truck-borne system based on it is integrated to measure the absolute gravity in the field. The measurement performance of this system is evaluated by applying it to measurements of the gravity field around the Xianlin reservoir in Hangzhou City of China. The internal and external coincidence accuracies of this measurement system were demonstrated to be 35.4 μGal and 76.7 μGal, respectively. Furthermore, the theoretical values of the measured eight points are calculated by using a forward modeling of a local high-resolution digital elevation model, and the calculated values are found to be in good agreement with the measured values. The results of this paper show that this home-made, truck-borne CAG system is reliable, and it is expected to improve the efficiency of gravity surveying in the field.
•Label-free was applied to analyze the changes in peptides and epitopes.•Mixed starter fermentation had more significant effect on digestion of milk protein.•Mixed starter hydrolyzed epitopes more ...widely, thereby reducing the risk of allergy.•Molecular simulation was used to evaluate the potential of epitopes.
Milk allergy is one of the most common food allergies, in which αS-casein is the major milk allergen. Under optimized conditions, mixed starter (containing Lactobacillus plantarum 7-2 and commercial starter) effectively degraded αS-casein of skimmed milk and reduced the pressure of stomach digestion. The fermented milk prepared by mixed starter was determined by ELISA, the antigenicity of αS-casein was reduced by 77.53%. Compared with the fermented milk prepared by commercial starter, label-free quantitative proteomics demonstrated that the mixed starter more efficiently degraded the epitopes of major milk allergens and influenced the digestion pattern of the fermented milk. Therefore, L. plantarum 7-2 shows positive potential in reducing the antigenicity of αS-casein and others. In addition, this study predicted that the new epitopes produced in the fermentation process could induce immunity using molecular simulation.
In coal mines, bolt loosening in the cage guide is affected by the harsh environmental factors and cage hoist vibration, leading to significant threats to work safety. It is crucial, to this effect, ...to successfully detect the status of multipoint bolts of guide structures. This paper proposes a system to monitor bolt status in harsh environments established based on the RFID technique. A proof-of-concept model was demonstrated consisting of a bolt gearing system, passive UHF RFID tags, a reader, and monitoring software. A tinfoil metal film is fixed on the retaining plate and an RFID tag bonded to a large gear, with the bolt to be detected fixed in the center of a smaller gear. The radio-frequency signal cannot be received by the reader if the tag is completely obscured by the tinfoil, and if the bolt is loose, the tag's antenna is exposed when the gear revolves. A radio-frequency signal that carries corresponding bolt's information is transmitted by the RFID tag to the RFID reader due to coil coupling, identifying loose bolt location and reporting them in the software. Confirmatory test results revealed that the system indeed successfully detects bolt loosening and comparative test results (based on a reed switch multipoint bolt loosening monitor system) provided valuable information regarding the strengths and weaknesses of the proposed system.
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