Oxidative Stress in BPH Savas, M; Verit, A; Ciftci, H ...
Journal of Nepal Medical Association,
2009 Jan-Mar, Letnik:
48, Številka:
173
Journal Article
Recenzirano
Odprti dostop
In the present study, we investigated the relationship between potency of oxidative stress and BPH and this may assist to contribute to the realistic explanation of the ethiopathogenesis of BPH.
...Seventy four newly diagnosed men with BPH (mean age: 54+/-11.2), who had not undergone any previous treatment for BPH, and 62 healthy volunteers (mean age: 55+/-14) were enrolled in the present study. To determine the antioxidative status of plasma, total antioxidant capacity (TAC) was calculated, and to determine the oxidative status of plasma (TOS) total peroxide levels were measured. The ratio of TAC to total peroxide was accepted as an indicator of oxidative stress (OSI). Data are presented as mean SD +/- unless specified. Student t-test and correlation analyses were used to evaluate the statistical significance differences in the median values recorded for all parameters between BPH and control group.
Plasma TAC TOS were found in patients and controls (1.70 +/- 0.32, 1.68 +/- 0.19 micromol Trolox Equiv./L), (12.48 +/- 1.98, 12.40 +/- 1.14 micromol / L) respectively. OSI was calculated as 7.57 +/- 1.91, 7.48 +/- 1.33, respectively. Plasma TAC, TOS and OSI levels were not found to be significantly difference between patients and control subjects (p>0.05, p>0.05, p>0.05).
The present study has shown that there were not relationship between potency of oxidative stress and BPH. Further well designed studies should be planned to find out whether the oxidative stress-related parameters play role in BPH as an interesting pathology in regard of the etiopathogenesis.
Epispadias surgery has mainly two components: bladder and genitourethral reconstruction. Herein, a novel vulvoplasty method, an alternative for the latter component, carried out in a rare case of ...female epispadias was presented. In a 6-year-old girl admitted with complaint of total incontinence, epispadias without evident extrophy associated with adequate bladder capacity was determined. Firstly the vulvoplasty in which a circumferencial skin flap around the urethral meatus was rolled backwards, and secondly bladder neck reconstruction was performed. The vulvoplasty resulted in sufficient cosmetic outcome and continence up to half an hour, and after cervicoplasty total day and night continence at rest or on exertion were obtained. It was concluded that this vulvoplasty with sufficient cosmetic outcome could be considered as a first stage operation in female epispadias, because it could facilitate bladder neck reconstruction by increasing urethral resistance, and contribute to continence.
Background: The purpose of the study was to compare the effect of varicocelectomy with that of clomiphene citrate on seminal improvement and pregnancy rates in patients with subclinical varicocele.
...Methods: A total of 42 infertile men with left subclinical varicocele were randomized to group I (21 patients, surgery) and group II (21 patients, medical therapy). The patients in group I were treated with varicocelectomy and those in group II with clomiphene citrate, 50 mg/day, orally. Sperm parameters (sperm density, motility and morphology) were recorded before and 6 months after beginning the treatment and pregnancy rates were estimated. In statistical analysis, paired and independent‐samples t‐tests, Kaplan–Meier and Log rank tests and Fisher's exact test were used.
Results: Mean ± SD age of the series was 32.7 ± 6.1 years, that of group I was 32.2 ± 5.5 years and that of group II was 33.1 ± 6.7 years (P = 0.680). All seminal parameters increased after both surgical and medical treatment, but only increases in sperm density and motility following varicocelectomy were statistically significant. Changes in seminal parameters between groups I and II were statistically insignificant. Pregnancy was seen in two cases in group I and in one in group II (P = 0.500). The cumulative pregnancy rates were 12.5% in group I and 6.7% in group II (P = 0.589).
Conclusions: Clomiphene citrate did not increase sperm density and motility as effectively as subclinical varicocelectomy, but there was no statistically significant difference between surgical and medical therapy methods in terms of seminal improvement and pregnancy rate.
Urethral calculus is a rare form of urolithiasis with an incidence lower than 0.3%. We determined the outcomes of 15 patients with urethral stone, of which 8 were pediatric, including an undiagnosed ...primary fossa navicularis calculus. Fifteen consecutive male patients, of whom eight were children, with urethral calculi were assessed between 2000 and 2005 with a mean of 19 months' follow-up. All stones were fusiform in shape and solitary. Acute urinary retention, interrupted or weak stream, pain (penile, urethral, perineal) and gross hematuria were the main presenting symptoms in 7 (46.7%), 4 (26.7%), 3 (20%) and 1 (6.6%) patient, respectively. Six of them had accompanying urethral pathologies such as stenosis (primary or with hypospadias) and diverticulum. Two patients were associated with upper urinary tract calculi but none of them secondary to bladder calculi. A 50-year-old patient with a primary urethral stone disease had urethral meatal stenosis accompanied by lifelong lower urinary tract symptoms. Unlike the past reports, urethral stones secondary to bladder calculi were decreasing, especially in the pediatric population. However, the pediatric patients in their first decade are still under risk secondary to the upper urinary tract calculi or the primary ones.
Penelitian ini bertujuan untuk mendeskripsikan; (1) keefektifan pendekatan open-ended dan CTL ditinjau dari hasil belajar kognitif; (2) keefektifan pendekatan open-ended dan CTL ditinjau dari hasil ...belajar afektif ;dan (3) perbedaan keefektifan pendekatan open-ended dan CTL ditinjau dari hasil belajar kognitif dan afektif. Penelitian ini merupakan penelitian eksperimen semu yang menggunakan dua kelompok eksperimen. One sample t-test digunakan untuk mendeskripsikan keefektifan pendekatan open-ended dan CTL pada masing-masing variabel. T2 Hotelling digunakan untuk mengetahui ada tidaknya perbedaan keefektifan pendekatan open-ended dan CTL secara simultan pada keempat variabel dependen. Hasil penelitian menunjukkan bahwa: (1) pendekatan open-ended dan CTL tidak efektif ditinjau dari hasil belajar kognitif; (2) pendekatan open-ended dan CTL efektif ditinjau dari hasil belajar afektif; dan (3) tidak ada perbedaan keefektifan antara pendekatan open-ended dan CTL ditinjau dari hasil belajar kognitif dan afektif. Kata kunci: open-ended, contextual teaching and learning, prestasi belajar, berpikir kreatif, sikap belajar matematika, minat belajar matematika.
Progress in female sexual dysfunction Verit, Fatma Ferda; Yeni, Ercan; Kafali, Hasan
Urologia internationalis,
2006, Letnik:
76, Številka:
1
Journal Article
Recenzirano
Female sexual dysfunction (FSD) is a significant age-related, progressive and highly prevalent problem that affects a substantial number of women that causes personal distress and has negative ...effects on quality of life and interpersonal relationships.
The female sexual response cycle consists of three phases: desire, arousal, and orgasm, and is initiated by non-adrenergic/non-cholinergic, e.g. vasoactive intestinal polypeptide and nitric oxide, neurotransmitters that maintain vascular and non-vascular smooth muscle relaxation resulting in increased pelvic blood flow, vaginal lubrication, and clitoral and labial engorgement. Furthermore, hormonal status may influence female sexual function. For the diagnosis of FSD, a detailed history should be taken initially, followed by a physical examination and laboratory studies.
Due to the fact that there has been little research and attention on FSD, our knowledge in this field is quite limited and there is still no approved therapy. Future advances in evaluation and treatment of female sexual problems are forthcoming.
In studying integer arithmetic operations, mentally retarded students use more learning using teaching materials that are still abstract and difficult to understand. The purpose of this study was to ...analyze the need for media use in the form of mathematics learning videos for mentally retarded students. This type of research is descriptive qualitative research. The data sources for this study were 3 teachers who taught mentally retarded students in class III elementary school (SD) at SDLB Negeri Metro. The instruments in this study were a needs questionnaire for the development of instructional video media, observation sheets and interview guidelines. Data collection techniques in this study were carried out by distributing questionnaires, observations, and interviews. Based on the results of the analysis and discussion, it can be interpreted that: (1) Media is needed in the form of mathematics learning videos that are in accordance with the conditions of mentally retarded students, (2) already know the numbers 1 to 10 and can add up to a value of 10, (3) it is still possible to use learning media with teacher guidance, and (4) students are more interested in using learning videos in learning mathematics.
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