Objectives
We aimed to evaluate the relationship between baseline renal function and changes in telomere length in Han Chinese.
Methods
The telomere restriction fragment (TRF) length of leukocytes in ...the peripheral blood was measured in healthy volunteers recruited in 2014. The estimated glomerular filtration rate (eGFR) was calculated based on serum creatinine (Scr) and serum cystatin C (CysC)-eGFRcys and eGFRScr-cys through the Cockcroft-Gault formula (eGFRC-G) or the Chronic Kidney Disease Epidemiology Collaboration (CKD-EPI / eGFRCKD-EPI) equation. The correlation between telomere length changes over time and renal function was analyzed.
Results
Leukocyte TRF lengths were negatively correlated to age (r = -0.393, p < 0.001) and serum CysC (r = -0.180, p < 0.01), while positively associated with eGFRCKD-EPI, eGFRC-G, eGFRcys, and eGFRScr-cys (r = 0.182, 0.122, 0.290, and 0.254 respectively, p < 0.01). The 3-year change of telomere length was 46 bp/years. When adjusted for age, the associations between telomere length changes and baseline, subsequent TRF lengths, and serum CysC were no longer present. No association was observed between TRF length changes and renal function.
Conclusion
The rate of telomere length changes was affected by age and baseline telomere length. The telomere length changes might be important markers for aging.
The measurement of the energy spectrum of cosmic ray helium nuclei from 70 GeV to 80 TeV using 4.5 years of data recorded by the Dark Matter Particle Explorer (DAMPE) is reported in this work. A ...hardening of the spectrum is observed at an energy of about 1.3 TeV, similar to previous observations. In addition, a spectral softening at about 34 TeV is revealed for the first time with large statistics and well controlled systematic uncertainties, with an overall significance of 4.3σ. The DAMPE spectral measurements of both cosmic protons and helium nuclei suggest a particle charge dependent softening energy, although with current uncertainties a dependence on the number of nucleons cannot be ruled out.
Electron resonant interaction with whistler mode waves is traditionally considered as one of the main drivers of radiation belt dynamics. The two main theoretical concepts available for its ...description are quasi‐linear theory of electron scattering by low‐amplitude waves and nonlinear theory of electron resonant trapping and phase bunching by intense waves. Both concepts successfully describe some aspects of wave‐particle interactions but predict significantly different timescales of relativistic electron acceleration. In this study, we investigate effects that can reduce the efficiency of nonlinear interactions and bridge the gap between the predictions of these two types of models. We examine the effects of random wave phase and frequency variations observed inside whistler mode wave packets on nonlinear interactions. Our results show that phase coherence and frequency fluctuations should be taken into account to accurately model electron nonlinear resonant acceleration and that, along with wave amplitude modulation, they may reduce acceleration rates to realistic, moderate levels.
Key Points
Chorus wave phase randomly fluctuates between subpackets inside longwave packets
Wave phase coherence significantly influences the efficiency of electron acceleration via nonlinear resonant interaction
Fluctuations of wave frequency within longwave packets similarly reduce the efficiency of nonlinear resonant electron acceleration
Abstract
We select the largest sample of Swift gamma-ray bursts (GRBs) so far to reexamine the classification in terms of time duration, hardness ratio, and physical collapse model. To analyze the ...sample selection effect, we divide the observed Swift GRB sample into four subsamples according to signal-to-noise level, spectral quality, and extended emission. First, we find that only the sample of Swift GRBs with well-measured peak energy can be evidently divided into two types at a boundary of ∼1 s, and other data sets are well described by three Gaussian functions. Using Swift GRBs with known redshift, a Kolmogorov–Smirnov test shows the intrinsic duration distributions of five data sets are equally distributed. Second, we ascertain in the plane of hardness ratio versus duration that the hardness ratio of short GRBs is significantly higher than those of middle classes and long GRBs, while the latter two components are the same in statistics, implying the so-called middle class to be artificial. Third, we apply a collapse model to discriminate the boundaries between collapse and noncollapse Swift bursts. It is interesting to find that a significant fraction, ≥30%, of Swift short GRBs could have originated from the collapsing progenitors, while all long GRBs are produced from the collapsars only. Finally, we point out that short GRBs with extended emission are the main contributors to the noncollapsar population with longer duration.
Large scale epitaxial growth and transfer of monolayer MoS2 has attracted great attention in recent years. Here, we report the wafer-scale epitaxial growth of highly oriented continuous and uniform ...monolayer MoS2 films on single-crystalline sapphire wafers by chemical vapor deposition (CVD) method. The epitaxial film is of high quality and stitched by many 0°, 60° domains and 60°-domain boundaries. Moreover, such wafer-scale monolayer MoS2 films can be transferred and stacked by a simple stamp-transfer process, and the substrate is reusable for subsequent growth. Our progress would facilitate the scalable fabrication of various electronic, valleytronic, and optoelectronic devices for practical applications.
A new alpha-emitting isotope U-214, produced by the fusion-evaporation reaction W-182(Ar-36,4n) U-214, was identified by employing the gas-filled recoil separator SHANS and the recoil-a correlation ...technique. More precise a-decay properties of even-even nuclei U-216,U-218 were also measured in the reactions of Ar-40, Ca-40 beams with W-180,W-182,W- 184 targets. By combining the experimental data, improved alpha-decay reduced widths delta(2) for the even-even Po-Pu nuclei in the vicinity of the magic neutron number N = 126 are deduced. Their systematic trends are discussed in terms of the N-p N-n scheme in order to study the influence of protonneutron interaction on a decay in this region of nuclei. It is strikingly found that the reduced widths of( 214,216)U are significantly enhanced by a factor of two as compared with the NpNn systematics for the 84 <= Z <= 90 and N < 126 even-even nuclei. The abnormal enhancement is interpreted by the strong monopole interaction between the valence protons and neutrons occupying the pi 1f (7/2) and nu 1f(5/2) spin-orbit partner orbits, which is supported by the large-scale shell model calculation.
We explore the mechanism of MeV and sub‐MeV electron precipitations into the atmosphere in the outer radiation belt, through quasi‐linear pitch‐angle scattering by electromagnetic ion cyclotron ...(EMIC) waves, when strong compressional Pc4–Pc5 ultralow‐frequency (ULF) waves are simultaneously present. Theoretically, the opposite magnetic field and density modulations produced by such ULF waves can significantly reduce the minimum electron energy for cyclotron resonance with EMIC waves, and this could potentially lead to the loss of lower energy (MeV and sub‐MeV) electrons. Statistical satellite observations of simultaneous, intense EMIC and ULF waves reveal the parameter domains most conducive to such lower energy electron losses, which are shown to be mostly located near the geosynchronous orbit. Selected events further suggest that such a mechanism could be efficient in the outer radiation belt and that even larger effects might occur during strong injections from the plasma sheet.
Key Points
Occurrence rates of simultaneous, intense EMIC and Pc4–Pc5 ULF waves in the outer radiation belt are provided
The minimum energy of electrons precipitated by EMIC waves could theoretically decrease by 25% due to ULF waves
We conjecture that EMIC waves could cause sub‐MeV electron loss in the presence of intense Pc5 ULF waves near L=6
Abstract
We report on analysis of observations of the bright transient X-ray pulsar Swift J0243.6+6124 obtained during its 2017-2018 giant outburst with Insight-HXMT, NuSTAR, and Swift observatories. ...We focus on the discovery of a sharp state transition of the timing and spectral properties of the source at super-Eddington accretion rates, which we associate with the transition of the accretion disk to a radiation pressure dominated (RPD) state, the first ever directly observed for magnetized neutron star. This transition occurs at slightly higher luminosity compared to already reported transition of the source from sub- to super-critical accretion regime associate with onset of an accretion column. We argue that this scenario can only be realized for comparatively weakly magnetized neutron star, not dissimilar to other ultra-luminous X-ray pulsars (ULPs), which accrete at similar rates. Further evidence for this conclusion is provided by the non-detection of the transition to the propeller state in quiescence which strongly implies compact magnetosphere and thus rules out magnetar-like fields.
The independent control of two magnetic electrodes and spin-coherent transport in magnetic tunnel junctions are strictly required for tunneling magnetoresistance, while junctions with only one ...ferromagnetic electrode exhibit tunneling anisotropic magnetoresistance dependent on the anisotropic density of states with no room temperature performance so far. Here, we report an alternative approach to obtaining tunneling anisotropic magnetoresistance in α'-FeRh-based junctions driven by the magnetic phase transition of α'-FeRh and resultantly large variation of the density of states in the vicinity of MgO tunneling barrier, referred to as phase transition tunneling anisotropic magnetoresistance. The junctions with only one α'-FeRh magnetic electrode show a magnetoresistance ratio up to 20% at room temperature. Both the polarity and magnitude of the phase transition tunneling anisotropic magnetoresistance can be modulated by interfacial engineering at the α'-FeRh/MgO interface. Besides the fundamental significance, our finding might add a different dimension to magnetic random access memory and antiferromagnet spintronics.Tunneling anisotropic magnetoresistance is promising for next generation memory devices but limited by the low efficiency and functioning temperature. Here the authors achieved 20% tunneling anisotropic magnetoresistance at room temperature in magnetic tunnel junctions with one α'-FeRh magnetic electrode.
In order to study the temporal and spatial variations of PM2.5 and its chemical compositions in the region of Beijing, Tianjin, and Hebei (BTH), PM2.5 samples were collected at four urban sites in ...Beijing (BJ), Tianjin (TJ), Shijiazhuang (SJZ), and Chengde (CD), and also one site at Shangdianzi (SDZ) regional background station over four seasons from 2009 to 2010. The samples were weighted for mass concentrations and analyzed in the laboratory for chemical profiles of 19 elements (Al, As, Ba, Ca, Cd, Co, Cr, Cu, Fe, K, Mg, Mn, Ni, P, Pb, Sr, Ti, V, and Zn), eight water-soluble inorganic ions (Na+ , NH4+ , K+ , Mg2+ , Ca2+ , Cl- , NO3- , and SO42- , and carbon fractions (OC and EC). The concentrations of PM2.5 and its major chemical species were season dependent and showed spatially similar characteristics in the plain area of BTH. The average annual concentrations of PM2.5 were 71.8-191.2 μg m-3 at the five sites, with more than 90% of sampling days exceeding 50 μg m-3 at BJ, TJ, and SJZ. PM2.5 pollution was most serious at SJZ, and the annual concentrations of PM2.5 , secondary inorganic ions, OC, EC, and most crustal elements were all highest. Due to stronger photochemical oxidation, the sum of concentrations of secondary inorganic ions (NH4+ , NO3- , and SO42- was highest in the summer at SDZ, BJ, TJ, and CD. Analysis of electric charges of water-soluble inorganic ions indicated the existence of nitric acid or hydrochloric acid in PM2.5 . For all five sites, the concentrations of OC, EC and also secondary organic carbon (SOC) in the spring and summer were lower than those in the autumn and winter. SOC had more percentages of increase than primary organic carbon (POC) during the winter. The sums of crustal elements (Al, Ca, Fe, Mg, Ti, Ba, and Sr) were higher in the spring and autumn owing to more days with blowing or floating dust. The concentrations of heavy metals were at higher levels in the BTH area by comparison with other studies. In Shijiazhuang and Chengde, the PM2.5 pollution was dominated by coal combustion. Motor vehicle exhausts and coal combustion emissions both played important roles in Tianjin PM2.5 pollution. However, motor vehicle exhausts had played a more important role in Beijing owing to the reduction of coal consumption and sharp increase of cars in recent years. At SDZ, regional transportation of air pollutants from southern urban areas was significant.
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