We evaluate the applicability and the effectiveness of the GPR attribute analysis for archaeological purposes and we test the attribute analysis on GPR data obtained in the river harbor area of the ...Aquileia Archaeological Park, NE Italy, where cultural heritage of the Roman imperial period is buried at different depths beneath a silty loam layer at an average depth not greater than 3–4m. A multi-attribute approach is used to characterize the subsurface through several attribute categories, including instantaneous, section and volume attributes applied to quantities related not only to the reflection amplitude, but also to frequency and phase or other more complex parameters. The results allow the identification of different buried archaeological remains, from brick walls to isolated stone chunks also in a very complex environment characterized by several interconnected or superimposed archaeological remains.
•Applicability of GPR attribute analysis for archaeological purposes was evaluated.•A multi-attribute was used to characterize the subsurface in Aquileia, NE Italy.•Instantaneous, section and volume attributes were included.•Different buried remains in a very complex environment were identified.
It has been verified that long noncoding RNAs (lncRNAs) have great effects on various biological behaviors of human diseases. Although more and more lncRNAs have been studied in human cancers, ...countless lncRNAs still need to be excavated. This study aims to investigate the impacts of lncRNA SNHG16 on proliferation and metastasis of human hemangioma endothelial cell (HemECs). qRT‐PCR analysis was carried out to explore the expression pattern of SNHG16, miR‐520d‐3p, and STAT3. The effect of SNHG16 on cell proliferation was detected by MTT and colony formation assay. Flow cytometry analysis was performed to test the apoptosis of HemECs cells. Migration and invasion of HemECs cells were determined and examined by transwell assays. Tube formation assay helped to observe the influence of SNHG16 expression on the vasoformation of HemECs cells. The correlations among SNHG16, miR‐520d‐3p, and STAT3 were certified by bioinformatics analysis, pull‐down assay, and dual‐luciferase reporter assay. Finally, rescue assays were conducted to demonstrate the effects of SNHG16‐miR‐520d‐3p‐STAT3 axis on biological behaviors of HemECs cell. SNHG16 was strongly expressed in proliferating phase hemangioma tissues and HemECs cells. Silenced SNHG16 negatively affected proliferation, migration, and invasion of HemECs cell. LncRNA SNHG16 acted as a ceRNA to upregulate STAT3 through binding with miR‐520d‐3p in HemECs cell. LncRNA SNHG16 acted as a ceRNA to drive proliferation, vasoformation, migration, and invasion of HemECs cells through modulating miR‐520d‐3p/STAT3 axis.
LncRNA SNHG16 acted as a ceRNA to drive proliferation, vasoformation, migration, and invasion of HemECs cells through miR‐520d‐3p/STAT3 axis.
The increase in travel mode options has led to changes in the travel decision-making behaviors of passengers and differences in spatial patterns of the markets of high-speed rail and air travel. ...Taking China’s central cities as the research subject, we analyze the spatial differentiation characteristics of high-speed rail and air transportation markets from a geographic perspective based on the passenger travel utility function. We analyze the influence on passenger travel decision-making behavior from the perspectives of the socioeconomic level and fare structure. The findings show that in the central city transportation market, passengers have a stronger preference for air travel. However, there are differences between regions, with high-speed rail dominating more in the partial north and air focusing on the partial south. As the value of time per capita increases, the dominant range of air travel gradually increases, while the dominant range of high-speed rail travel is compressed to some extent. An increase in fares does not cause a significant decrease in air demand; however, a reduction in fares leads to an increase in air passenger travel satisfaction.
Archaeological GPR data from antennas of different frequencies allow the identification of buried cultural heritage at different scales. Therefore, multi-frequency GPR systems are recommended for ...complicated subsurface archaeological conditions. GPR data fusion approaches, automatically or semi-automatically, can integrate data measurements from different frequency antennas, combine them into a single representation, and partially overcome the unavoidable trade-off between penetration and resolution. We propose an adaptively weighted fusion method for multi-frequency GPR data based on genetic algorithms (GAs). In order to evaluate the feasibility and the effectiveness of the strategy for archaeological prospection, we tested the procedure on GPR datasets acquired in two totally different archaeological conditions: rammed layers of an ancient wall, in Henan Province, China, and complex and elusive prehistoric archaeological features within a natural stratigraphic sequence on the volcanic Stromboli Island, Italy. The results demonstrate that the proposed strategy can maximize the information content of GPR profiles, enhancing the GPR interpretation possibilities in an automatic and objective way for different targets and in different subsurface conditions.
This paper uses the Multidimensional Fatigue Inventory (MFI-16) to investigate the fatigue status of pilots, and the reliability and validity of the scale are tested by Cronbach's α and exploratory ...factor analysis. The founding shows that mild fatigue and above accounted for 67.7%. For further quantify the impact of different flights on pilots' fatigue, research improves the fatigue coefficient model based on the results of pilot fatigue feeling questionnaire. Combined with multifactor analysis of variance and multiple linear regression, it is found that the independent variables have different and positive effects on the dependent variables, and there is no multicollinearity. Through the actual test, its accuracy is improved by 16.7% compared with the original model.
Background
Febrile seizures (FS) usually occur in childhood and may cause irreversible neuronal damage, cognitive functional defects, and an increase in the risk of epilepsy later in life. ...Anti-epileptic drugs (AEDs), currently used to treat FS in children, can relieve seizures. However, their effects in preventing the risk of developing epilepsy in later life are unsatisfactory. Moreover, AEDs may damage child brain development. Here, we evaluated the efficiency of xenon in treating prolonged FS (PFS) and preventing epilepsy in Sprague-Dawley pups.
Methods
Prolonged FS was induced by hyperthermic treatment. After 90 min of PFS, the pups in the xenon treatment group were immediately treated with 70% xenon/21% oxygen/9% nitrogen for 60 min. The levels of glutamate, mitochondrial oxidative stress, mitophagy, and neuronal injury, seizures, learning, and memory functions were measured at specific time points.
Results
Neonatal period PFS led to spontaneous seizure, learning and memory dysfunction, accompanied by increased levels of glutamate, mitochondrial oxidative stress, mitophagy, and neuronal injury. Xenon treatment alleviated the changes caused by PFS and reduced the risk of PFS developing into epilepsy later.
Conclusion
Our results suggest that xenon inhalation could be a potential therapeutic strategy to attenuate neuronal injury and prevent epilepsy in patients with FS.
Due to the rapid growth of the global economy, energy consumption has been steadily increasing, leading to increasing issues such as energy shortages and environmental concerns. Biomass energy, a ...critical renewable energy source, plays a vital role in advancing low-carbon energy development and resource sustainability. In this study, experiments were conducted to study the migration of C, H, and N elements of corn straw during the microwave heating process, and the effects of residence time, heating temperature, and microwave power were also investigated. The results showed that when the temperature rose, both the proportion of C and H elements fluctuated slightly. Specifically, when the temperature rose from 75 °C to 275 °C, there was a 1.02% increase in the proportion of the C element and a 0.25% decrease in the proportion of the H element. Residence time appeared to be a significant factor influencing the changes in C, H, and N elements. For a 40 min residence time, the proportion of the C element increased from 31.77% to 35.36%, while the proportion of the H element decreased from 4.50% to 3.83%. When there was an increase in the microwave power between 160 W and 200 W, higher temperatures were reached in the samples, leading to the carbonization process of corn straw being more complete. Consequently, the proportion of the C element rose with extended residence time, whereas the proportion of the H element decreased as the residence time increased.
Ground penetrating Radar (GPR) is an efficient tool for subsurface geophysical investigations, particularly at shallow depths. The non-destructiveness, cost efficiency, and data reliability are the ...important factors that make it an ideal tool for the shallow subsurface investigations. Present study encompasses; variations in central frequency of transmitting and receiving GPR antennas (Tx-Rx) have been analyzed and frequency band adjustment match filters are fabricated and tested accordingly. Normally, the frequency of both the antennas remains similar to each other whereas in this study we have experimentally changed the frequencies of Tx-Rx and deduce the response. Instead of normally adopted three pairs, a total of nine Tx-Rx pairs were made from 50MHz, 100MHz, and 200MHz antennas. The experimental data was acquired at the designated near surface geophysics test site of the Zhejiang University, Hangzhou, China. After the impulse response analysis of acquired data through conventional as well as varied Tx-Rx pairs, different swap effects were observed. The frequency band and exploration depth are influenced by transmitting frequencies rather than the receiving frequencies. The impact of receiving frequencies was noticed on the resolution; the more noises were observed using the combination of high frequency transmitting with respect to low frequency receiving. On the basis of above said variable results we have fabricated two frequency band adjustment match filters, the constant frequency transmitting (CFT) and the variable frequency transmitting (VFT) frequency band adjustment match filters. By the principle, the lower and higher frequency components were matched and then incorporated with intermediate one. Therefore, this study reveals that a Tx-Rx combination of low frequency transmitting with high frequency receiving is a better choice. Moreover, both the filters provide better radargram than raw one, the result of VFT frequency band adjustment filter is much better than CFT frequency band adjustment filter.
•The variable frequency GPR antenna pairing scheme provides more choice in selection of antenna frequency for survey of an area.•Major reason behind the usefulness of the scheme is the swap effect of all antenna pairs which is different from each other.•The frequency bandwidths clarify the influence and impact of transmitting frequency is greater on the data than the receiving one.•Whenever, transmitting frequencies are higher than the receiving frequencies, the random interference (noise) is greater.•The frequency band adjustment match filters efficiently enhance the GPR data quality.•The output results of VFT band adjustment match filter are better than the CFT.
Activated carbon (AC) is widely utilized in water treatment, gas adsorption, and purification as well as the protection of environment due to the characteristics of prominent catalytic and adsorbent ...effect. The heating performances are therefore of significant importance for the further applications. The main objective of this study was therefore to detail the heating performance of activated carbon in microwave field, and the factors affecting the heating performance were also explored. In this study, the heating performance of AC as affected by microwave power (400, 450, 500, 550, and 600 W), feeding load (5, 10, 15, 20, and 25 g), and reactor volume (50, 100, 150, 200, and 250 mL) were detailed and reported. The results showed that when the microwave powers were 400, 450, 500, 550, and 600 W, the temperatures of AC increased to the desired value (about 200 °C) within 90, 85, 70, 60, and 35 s with average heating rates of 2.0, 2.2, 2.8, 3.0, and 5.9 °C/s, respectively. When the feeding loads were 5, 10, 15, 20, and 25 g, the temperatures of AC increased to desired temperature within 40, 70, 60, 50, and 50 s with average heating rates of 4.2, 2.8, 3.1, 3.50, and 3.55 °C/s, respectively. When the reactor volumes were 50, 100, 150, 200, and 250 mL, the temperatures of AC increased to the desired temperature within 25, 60, 70, 70, and 160 s with average heating rates of 7.6, 3.3, 2.8, 2.6, and 1.2 °C/s, respectively. In general, the faster heating rate of activated carbon was achieved at higher microwave power, more feeding load, and smaller reactor volume. Fitting formulae were given to predict the transient temperatures of AC in the microwave field, and the relative errors were in the ranges of −15.4~12.4%, −15.4~13.5% and −18.7~12.4% at different microwave powers, feeding loads, and reactor volumes, respectively.
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