The results of treatment of 443 patients with endometrial carcinoma (surgery--101 (22.8%), combined therapy--183 (41.3%) and complex therapy--159 (35.9%) are presented. The role of ...clinico-morphological factors, including steroid hormone receptor levels in tumor, is discussed with a view to combat tumor.
It is shown as necessary to create specialized aid to cancer families in the general structure of oncological service. The results of 2-year clinical-genetic monitoring of high-risk group relative to ...ovarian, breast and endometrial cancer are presented.
Comparative investigation of prostaglandin E (PGE) levels in primary malignant and benign epithelial tumors, metastases, and normal tissue of the ovaries has revealed more significant variations in ...PGE levels in malignant tumors than in benign ones. PGE content was reliably higher in adenocarcinomas as against benign tumors and normal ovarian tissue. No noticeable differences in PGE levels of benign tumors and normal tissue were revealed. The possibility of using arachidonic acid cyclooxygenase metabolism blockers in therapy of ovarian carcinoma, besides the common methods of treatment, is discussed.
Formation of registers of families afflicted by tumors of certain sites and dynamic follow-up of "healthy" members of such families is a new approach to early diagnosis and prevention of cancer. The ...results of a clinico-genetic study of hormone-dependent tumors of the female genitals and breast served as a basis for the development of a pattern of medico-genetic follow-up which, in turn, may facilitate integration of the above method with treatment for cancer of said and other sites.
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