The aim of this study was to verify the effectiveness and safety of the 808-nm wavelength for use on benign lesions of the oral cavity that are stained with toluidine blue solution.
The toluidine ...blue solution according to Mashberg is used in stomatology for the detection of leuko-erythroplasic lesions. In our experience, we have used it to stain even serous cysts, angiomas, and fibromas. We chose a 808-nm wavelength emitted from a power diode laser, because it is well absorbed by the blue color and barely by the healthy mucosa. The non-contact photocoagulation kept the surrounding borders intact when we used the pulsed-emission, 50 ms 7 W, without anesthesia. No sutures were needed. The leukoplasic borders of the lesions were histologically examined before and after the treatment.
The vaporized lesions healed completely in about 5-7 days without any kind of treatment, leaving some slight elastic white scars. A mild edema-erythema followed the treatment for 5-7 days.
The selective results confirm the effectiveness of this therapeutic procedure on pigmented benign lesions, pre-treated with exogenous chromophores and photocoagulated without bleeding, with a minimum energy 808-nm laser.
We conducted this study to evaluate the immediate venous morphologic alterations produced in the great saphenous veins by the endovenous diode 808-nm laser used for the treatment of superficial ...venous insufficiency and varicose veins of the lower limbs and to clarify the clinical implications of the histologic findings.
Chosen for the study were 24 limbs of 16 patients with CEAP classification 3 to 6, ultrasound-documented greater saphenous insufficiency, and venous diameters between 3.9 mm and 17 mm (mean, 8.04 mm) without phlebitis, saphenous aneurysms, congenital malformations, or deep venous insufficiency. All limbs underwent surgical saphenofemoral disconnection, and the greater saphenous vein was treated with an endovenous diode 808-nm laser by continuous emission at 8 to 12 W and variable retraction speed (</>1 mm/s). Spinal or local, but not tumescent, anesthesia was used. Twenty-nine specimens (3 to 5 cm long) of 24 proximal greater saphenous and five anterior accessory saphenous veins were excised and studied by light microscopy for diameter and thickness of the venous wall, extent of injury into the intima, media, and adventitia, as well as penetration of thermal damage.
The histologic evaluation showed thermal injury to the intima in all specimens and full-thickness intimal injury in 22 specimens (75%); the average penetration of thermal injury in 29 specimens was 194.40 μm (range, 10 to 900 μm; 14.61% of the mean wall thickness); complete intimal circumference injury occurred in 8 specimen veins <10 mm in diameter (27.5%), full thickness damage in 6 (20.7%), and perforation in 2 (6.9%).
Saphenous ablation using 808-nm laser by variable retraction speed, combined with saphenofemoral interruption, leads to sufficient vein wall injury to assure venous occlusion. Full thickness thermal injury or perforation is infrequent. Optimal results can be obtained in veins <10 mm in diameter.
The aim of our study was to follow-up 15 patients with stretch marks treated positively with the CuBr laser (577-511 nm) in 1998-99 and followed-up for 2 years.
The patients were Italian women, young ...to middle age (average 30 years old), with skin coloration classified as Fitzpatrick II-III. Biopsies were taken on some patients before the treatment and 1 month after the first treatment. Double-blind histological, histochemical and photographic evaluation was performed. Results obtained as well as to the contradictory effects reported elsewhere in the literature were compared.
On average, the results were positive and there were some pathogenic considerations that justified the use of laser.
Our purpose was to evaluate the effectiveness of cleansing by CO2 laser with a rotating mirror scanner in accelerating ulcer granulation and reducing sensitization, bleeding, and the need for painful ...medications.
Cleansing, the first step in treating phlebostatic ulcers, may be performed with a defocussed CO2 laser, but laser-to-target distance, technique, and duration of the procedure may vary.
We studied 20 patients, ages 38-85, with "common" phlebostatic ulcers showing a tendency not to granulate. The patients were divided into two groups by sex (7 females and 3 males) and by size of ulcer. The first group was treated using the CO2 laser and rotating mirror scanner; the second was treated surgically with scissors and tweezers. In both groups debridement was followed by mobile and fixed elastocompressing bandage, mobilization, and phlebotonics. Six patients in the first group and four in the second subsequently underwent short stripping to correct the incompetent saphenous circulation.
Ulcer cleansing was achieved in all 20 cases. In the laser group, the treatment was well tolerated by 9 patients and granulation was achieved in 10 days on average; in the second group, cleansing was very painful in 5 cases and granulation was achieved in 25 days on average. Both groups had good cicatrization at 3 months after elastocompression, zinc dioxide medication, mobilization, and phlebotonics. The 6-month follow-up revealed only one recurrence--a small ulcer at a different location--in the first group and no cases of recurrence in the second.
Cleansing by CO2 laser and rotating mirror scanner allows the acceleration of ulcer granulation and reduces sensitization, bleeding, and the need for painful and costly medications.
The Authors have discussed the importance of ER/PR assay in breast cancer care. 162 patients were studied. The dextran-coated charcoal technique was used as the standard most readily available. The ...Authors point out the importance of specimen handling as is shown by time-decay studies, and the differences in ER/PR level at the time of the biopsy and mastectomy cut-section, and its eventual influence to better understanding assay results. The establishment of a center of control between different labs would also help in the development of more exact regimens for cancer care.
Bilateral carcinoma of the breast Gabrielli, F; Domeniconi, R; Adovasio, R ...
Minerva chirurgica,
1981-Feb-28, Letnik:
36, Številka:
4
Journal Article
In the light of literature and personal experience the Authors analyse the problem of bilateral breast cancer. Distinction between primary cancer (synchronous or metachronous) and metastasis in the ...second breast is made on the bases of clinical and histological criteria. Lobular cancer, either in situ of infiltrating, has a higher incidence of bilaterality. Aethiology, incidence, prognostic significance of the second cancer are briefly discussed; particularly, it is emphasized that there is a "high risk" group of patients in which the incidence of primary contralateral cancer is much higher. The Authors stress the importance of clinical examination of the other breast at the time of initial mastectomy for a proven breast cancer. The risk of metachronous cancer may be prevented by prophylactic contralateral mastectomy in the "high risk" patients or by random biopsy of the opposite breast in all the patients undergoing surgical therapy for cancer in the first breast. It is opinion of the Authors that early diagnosis may be also obtained if the patients are carefully followed by regular physical examinations and by diagnostic aids (mammography, ultrasonography, thermography).
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