Binge eating is the most common form of disordered eating associated with obesity, reduced quality of life, and medical and psychological comorbidities. It therefore affects the well-being of ...individuals. This underscores the fact that it is a serious public health problem. The study aimed to investigate binge eating and anxiety across gender, age and body mass index in a large population sample of adults in Slovenia.
A total of 3,310 adult volunteers participated in this cross-sectional study. Questionnaires, including a binge eating and anxiety scale and an eating behaviour questionnaire, were completed by 1,487 subjects (90.9% female, ages 18 to 69).
The frequency of reported binge eating was 29.9%, with 9.8% of participants reporting severe binge eating, and the presence of overweight and obesity was high (41.8%). BMI was associated with this problematic eating, and explained 5.4% of the variation in binge eating. Importantly, anxiety was the most important factor related to binge eating, with younger participants and women reporting significantly more anxiety.
The high presence of binge eating, obesity and anxiety in the Slovenian population-based sample is worrying. Anxiety is clearly an important factor in understanding the relationship between negative affect and binge eating, as it accounts for a greater proportion of the variance in binge eating symptoms than BMI. Particularly concerning was the fact that the youngest participants showed the greatest anxiety. Targeting anxious adolescents and females is important from a health perspective because it can impact the physical and mental health of the population in the long term.
The aim of the study is to show the differences between the measured and estimated values of resting energy expenditure and any changes occurring after the 6-month weight loss intervention program.
...We included 33 healthy adults aged 25-49 years with an average body mass index 29.1±2.7 kg/m 2 for female and 29.8±2.8 kg/m
for male. The measured resting energy expenditure was obtained by indirect calorimeter MedGem® Microlife and estimated resting energy expenditure by the Harris-Benedict equation, the Mifflin-St Jeor equation, the Owen equation, the Wright equation, and by the Tanita body composition analyser. All measurements and calculations were carried out before and after the 6-month intervention. Results were compared using paired t-tests. P value less than 0.05 was considered statistically significant.
A comparison of the measured resting energy expenditure of female subjects with the estimated resting energy expenditure using the Harris-Benedict equation, the Mifflin-St Jeor equation and the Wright equation showed a statistically significant difference. A comparison of the measured resting energy expenditure of male subjects with the estimated resting energy expenditure using the Harris-Benedict equation and the Wright equation showed a statistically significant difference. There was a significant difference in the measured resting energy expenditure and estimated resting energy expenditure using Tanita.
We concluded that the most comparable equation for our sample was the Owen's equation. After losing weight, the measured resting energy expenditure has decreased, which must be taken into account in further diet therapy.
To examine the effects of various maternal and neonatal perinatal factors on the child's body mass index (BMI) and physical fitness at school-age.
Data from two registries, the SLOfit database (a ...national surveillance system of children's motor and physical development) and Slovenian National Perinatal Information System (NPIS) were analysed. Perinatal data for 2,929 children born in 2008 were linked to results of SLOfit testing of these children in 2016. Linear regression analysis was used to assess the potential relationship between several perinatal factors (very preterm birth, birth mass, maternal age, hypertensive disorders of pregnancy, gestational diabetes, parity, plurality, maternal pre-pregnancy BMI, mode of delivery, presentation, Apgar score at 5 minutes, and admission to a neonatal intensive care unit (NICU)) and child's BMI or child's physical fitness index (PFI) at the age of eight years. We also included child's school grade and maternal educational level in the analysis. A p value <0.05 was considered statistically significant.
Children born to mothers with lower pre-pregnancy BMI and higher education had lower BMI and higher PFI (p<0.001) at school-age. Physical fitness was also inversely associated with nulliparity (p<0.001) and NICU admission (p=0.020).
Among all perinatal factors studied, higher maternal education and lower pre-pregnancy BMI seem to be the most significant determinants of child's BMI and physical fitness at school-age.
Maščobno tkivo ima vlogo pri številnih endokrinih in presnovnih procesih. Lepin je bil med prvimi odkritimi dejavniki iz maščobnega tkiva, ki delujejo avto-, para- in endokrino. Od opredelitve ...leptina so odkrili še številne druge dejavnike, od katerih se nekateri izločajo iz maščobnih celic, nekateri pa iz drugih celic maščobnega tkiva.
Adipose tissue is implicated in many endocrine and metabolic processes. Leptin was among the first identified adipose-secreted factors, which act in an auto-, para- and endocrine manner. Since ...leptin, many other adipose tissue factors were determined, some primarily secreted from the adipocytes, some from other cells of the adipose tissue.
So-called adipokines are not only involved in obesity and its complications, as are insulin resistance, type 2 diabetes and other components of the metabolic syndrome, but also in growth, reproduction, bone metabolism, immune response, cancer development and many other important biological processes. Research in the field of adipokines has revealed new insights into the physiological and pathophysiologal processes and opened new therapeutic possibilities. In the present article, a special emphasis is devoted to research in children and adolescents.
Maščobno tkivo ima vlogo pri številnih endokrinih in presnovnih procesih. Lepin je bil med prvimi odkritimi dejavniki iz maščobnega tkiva, ki delujejo avto-, para- in endokrino. Od opredelitve leptina so odkrili še številne druge dejavnike, od katerih se nekateri izločajo iz maščobnih celic, nekateri pa iz drugih celic maščobnega tkiva.
Tako imenovani adipokini niso povezani le z debelostjo in njenimi zapleti, kot so rezistenca proti inzulinu, sladkorna bolezen tipa 2 in druge komponente metabolnega sindroma, temveč tudi z rastjo, razmnoževanjem, presnovo kosti, imunskim odzivom, razvojem rakavih bolezni in mnogimi drugimi pomembnimi biološkimi procesi. Raziskave na področju adipokinov so opredelile nove fiziološke in patofiziološke procese in odprle nove možnosti zdravljenja. V tem prispevku poseben poudarek namenjamo raziskavam pri otrocih in mladostnikih.
Izhodišča: V razvitem svetu se zaznava izrazit porast prekomerne prehranjenosti in debelosti med otroki in mladostniki. V raziskavi smo analizirali prekomerno prehranjenost in debelost med ...ljubljanskimi osnovnošolci, starimi od sedem do štirinajst let, v obdobju po osamosvojitvi Slovenije.
Economic aspects of obesity prevention Cecchini, Michele; Sassi, Franco
Bilten : ekonomika, organizacija, informatika v zdravstvu,
01/2011, Letnik:
27, Številka:
2
Journal Article
Recenzirano
Odprti dostop
Governments in OECD countries have intervened in a variety of ways to improve diets, increase physical activity and tackle obesity in recent years. The preventive interventions assessed in this ...analysis are drawn from the most commonly used approaches, including: health education and health promotion (mass media campaigns, school-based interventions, worksite interventions); regulation and fiscal measures (fiscal measures altering the prices of healthy and unhealthy foods, regulation of food advertising to children and mandatory nutrition labelling); and, counselling of individuals at risk in primary care. This report examines the characteristics, the costs and the relative success of each approach in improving health outcomes and social disparities in health, with specific reference to the European context.
V zadnjih letih so vlade držav OECD (Organizacije za gospodarsko sodelovanje in razvoj) posredovale na različne načine, da bi izboljšale prehranjevanje, spodbudile povečanje telesne dejavnosti v boju proti debelosti. Preventivni ukrepi, ocenjeni v tej analizi, so sestavljeni iz naslednjih najpogosteje uporabljenih pristopov: zdravstvena vzgoja in promocija zdravja (akcije javnega obveščanja, v šolah in na delovnem mestu), pravna ureditev in fiskalni ukrepi (fiskalni ukrepi spreminjajo cene zdrave in nezdrave hrane, urejajo oglaševanje hrane za otroke in predpisujejo obvezno označevanje hranilne vrednosti) ter svetovanje posameznikom, ki sodijo v bolj izpostavljene skupine, na ravni primarnega zdravstva. Prispevek preučuje lastnosti, stroške in relativni uspeh vsakega pristopa pri izboljšanju zdravstvenih rezultatov in socialnih razlik v zdravju s posebnim poudarkom na evropsko okolje.
Porast debelosti v moderni družbi je povezan z večjo pojavnostjo z debelostjo povezanih bolezni in predstavlja veliko finančno breme za javno zdravstvo. Pomembno odkritje na področju mikrobiologije ...prebavnega trakta sesalcev je povezano z vlogo prebavne mikrobiote pri razvoju debelosti. Z novimi molekularnimi metodami in poskusi z gnotobiotskimi živalmi so do neke mere pojasnili udeležbo prebavne mikrobiote pri uravnavanju telesne mase in energijskega ravnovesja gostitelja. Prebavna mikrobiota vpliva na vnos hranil in porabo energije iz hrane in pospešuje shranjevanje le-te v maščobna tkiva s procesi fermentacije, olajšane absorpcije in tudi z vplivom na izražanje gostiteljevih genov (protein Fiaf) ter na aktivnost gostiteljevih encimov (proteinska kinaza AMPK). Pri debelih miših in ljudeh je prebavna mikrobiota dokazano bolj učinkovita pri izkoriščanju energije iz hrane kot pri suhih. osebkih. Obstajajo značilne razlike v sestavi mikrobne združbe glede na debel oz. suh fenotip. V prebavilih debelih živali in ljudi se dosledno kaže povišan delež predstavnikov bakterij iz debla Firmicutes na račun zmanjšanja predstavnikov debla Bacteroidetes, obe prevladujoči debli pa v prebavilih sesalcev skupaj predstavljata do 90 % vseh bakterij. Izkazalo se je, da je prebavna mikrobiota udeležena tudi pri patofiziologiji debelosti preko dejavnikov, kot je mikrobni LPS. Rezultati raziskav kažejo, da lahko spremembe deleža maščob v hrani vplivajo na sestavo mikrobne združbe ter da te spremembe vplivajo na pojavnost metabolnih bolezni. Odpira se novo področje manipulacije prebavne mikrobiote za zdravljenje debelosti in z njo povezanih bolezni.
The increased prevalence of obesity in modern society is associated with incidence of obesity related diseases and represents a financial burden on public health. Important discovery in the field of microbial ecology of the gut was the possible involvement of the gut microbiota in obesity development. Using new molecular techniques and gnotobiotic animal models has revealed the relation between the regulation of body mass and energy balance of the host with the microbial community of the gut. Gut microbiota affects nutrient intake, facilitate the extraction of energy from food and promote storage of the calories in host adipose tissue through processes of fermentation, absorption and through the effect on the expression of host genes (e.g. Fiaf) and the activity of host enzymes (e.g. AMPK). In obese mice and humans the gut microbiota is clearly able to obtain energy from food more effectively as in the lean subjects. There are significant differences in the composition of microbial communities in relation to fat vs. lean phenotype. In the gut of obese animals and humans the increased proportion of the Firmicutes at the expense on Bacteroidetes was consistently detected. Both are the dominant bacterial groups in mammalian gastrointestinal tract, accounting together for 90% of all bacteria. It has been shown that gut microbiota is involved also in patophysiology of obesity through factors such as microbial LPS. Existing results show that high fat diet can affect the composition of microbial community in the gut and that these changes can further affect the incidence of metabolic disease. This evidence potentially opens a new field of manipulation of the gut microbiota as a new strategy to treat obesity and related diseases.