In his target article ‘The Illusions of the Modern Synthesis’, Denis Noble argues that the Modern Synthesis is undermined by the major findings of molecular biology. The supposed falsification of ...Weisman’s Barrier and of standard interpretations of Francis Crick’s Central Dogma has paved the way for Lamarckian forms of inheritance which are prohibited by that theory of evolution. I argue that August Weismann postulated two barriers against two kinds of Lamarckism. However, his second barrier was speculative. It was made more concrete through the articulation of Francis Crick’s Central Dogma. These two barriers still preclude Lamarckism or Lamarckian forms of inheritance, as understood by Weismann.
Memories on film Catchpole, Jessica
Lancet neurology,
10/2023, Letnik:
22, Številka:
10
Journal Article
Recenzirano
Odprti dostop
Previous events have explored wide-ranging topics, including discussions about psychosis after a screening of A Beautiful Mind, and debating the ethical and societal effects of genetic engineering ...after watching the movie Gattaca. The film screened at the finale event was Eternal Sunshine of the Spotless Mind, in which two people—Joel (Jim Carrey) and Clementine (Kate Winslet)—undergo a procedure to forget each other when their relationship ends. The panel also included neuropsychologist Vaughan Bell (South London and Maudsley NHS Trust and University College London, London, UK), neuroscientist Julia Harris (The Francis Crick Institute, London, UK), and artist and member of Headway East London, Dave Mercer, who lives with memory loss as the result of a brain injury.
Although F. Scott Fitzgerald remains one of the most recognizable literary figures of the twentieth century, his legendary life - including his tempestuous romance with his wife and muse Zelda - ...continues to overshadow his art. However glamorous his image as the poet laureate of the 1920s, he was first and foremost a great writer with a gift for fluid, elegant prose. This introduction reminds readers why Fitzgerald deserves his preeminent place in literary history. It discusses not only his best-known works, The Great Gatsby (1925) and Tender Is the Night (1934), but the full scope of his output, including his other novels and his short stories. This book introduces new readers and students of Fitzgerald to his trademark themes, his memorable characters, his significant plots, the literary modes and genres from which he borrowed, and his inimitable style.
Este artigo pretende examinar a visão de modernidade encenada no projeto poético de Francis Ponge, levando em consideração alguns modelos literários e culturais presentes na tradição francesa. ...Trata-se, assim, de tentar entender de que modo o poeta problematiza a ideia que temos da poesia ao escapar das dicotomias que caracterizariam as definições de modernidade em oposição a certo passado. Para tanto, pretende-se investigar a articulação entre os textos "rascunhados" de Ponge --que compõem os livros Comment une figue de paroles et pourquoi e La Table--e o desenvolvimento do olhar lançado à matéria na era do surgimento da anatomia a partir do século XVI. Tal aproximação permite também um diálogo com o conceito de serendipidade, cujo paradigma indiciário aponta para a linguagem como conjunto de indícios a serem seguidos. Palavras-chave: Francis Ponge; poesia moderna; serendipidade; anatomia. This article seeks to examine the vision of modernity staged in Francis Ponge's poetic project. taking into account some of the literary and cultural models present in the French tradition. It is thus an attempt to understand how the poet problematizes the idea we have of poetry by escaping from the dichotomies that would characterize the definitions of modernity in opposition to a certain past. To this end, we aim to examine the articulation between Ponge's "drafts"--which form part of his books Comment une figue de parole et pourquoi and La Table--and the development of a gaze fixed on matter in the era of the appearance of anatomy from the sixteenth century onwards. Such an approach also enables a dialogue with the concept of serendipity, whose indicium paradigm points to language as a set of pointers to be followed. Keywords: Francis Ponge; modern poetry; serendipity; anatomy. Cet article a pour but d'examiner la vision de modernité mise en scène dans le projet poétique de Francis Ponge, en prenant en compte quelques modèles littéraires et culturels présents dans la tradition française. Il s'agit donc, d'essayer de comprendre de quelle manière le poète problématise l'idée qu'on fait de la poésie tout en évitant des dichotomies qui caractériseraient les définitions de modernité en opposition à un certain passé. Pour ce faire, il faut investiguer la relation entre les "brouillons" de Ponge--qui composent les livres Comment une figue de paroles et pourquoi e La Table--et le développement du regard vers la matière à l'époque de l'avènement de l'anatomie à partir du XVIe siècle. Tel croisement permet également d'établir un dialogue avec le concept de sérendipité, dont le paradigme indiciaire montre le langage comme un ensemble d'indices à être poursuivis. Mots-clés: Francis Ponge; poésie moderne; sérendipité; anatomie.
Bringing together established Fitzgerald scholars from the United Kingdom, Europe and North America, this collection offers eleven new readings of F. Scott Fitzgerald’s 1934 novel, Tender is the ...Night. Contributors include editors of the F. Scott Fitzgerald Review, the general editor of the Cambridge Edition of the Writings of F. Scott Fitzgerald, members of the Fitzgerald Society Executive, and the directors of the biennial F. Scott Fitzgerald conference.
The paper presents the recent trends and ideas for flexible operation of Francis turbines using Full-Size Frequency Converter (FSFC) or Doubly-Fed Induction Machine (DFIM) technology for ...variable-speed operation. This technology allows for the speed of the runner to be adjusted in order to maximize the efficiency and/or reduce dynamic loads of the turbine according to the available head and power generation demands. Continuous speed variation of up to ±10% of the design rotational speed can be achieved with the DFIM technology, while for FSFC there is no such limit by the technology itself. For off-design operation of Francis turbines, depending on the variation of the head and the hydraulic design, the hydraulic efficiency gain from variable-speed operation compared to its synchronous-speed representative can go up to 10%. In addition, turbines operated at variable-speed can have significant improvement in the response times for power output variations, being able to utilize the flywheel effect from the rotating masses (also known as synthetic inertia). This review focuses on the investigations and the achievements done so far and does not tend to enter deeply into each multidisciplinary aspect of the technology itself. Possible further development directions are also disclosed, mainly towards the hydraulic design and optimization of variable-speed Francis turbines.
•Variable-speed turbines can improve off-design efficiency up to 10% for larger head variations.•Variable-speed operation is done by decoupling the stator from the grid or decoupling the rotor magnetic field from the rotor.•Variable-speed operation gives precise, faster and smoother response to load variations.•Both deterministic and stochastic pressure pulsations are dependent on the speed variations.•Design speed of the runner should be a synchronous value due to the need of bypassing the variable-speed equipment.
There are multiple causes. ...we draw attention towards that, which means the foundation of the ecumenical movement, namely the dialogue of love and the dialogue of truth, which should not be ...mistaken for the quantitative negotiations for Christian unity. ...we promote the cause of spiritual ecumenism. Pope Francis in 2019 on his visit in Romania spoke about the ecumenism of blood, of the poor, and of prayer. Keywords: ecumenism, dialogue of love, dialogue of truth, Christian unity, Pope Francis.
The central question of this article concerns Hegel's concept of recognition (Anerkennung) and its meaning for the current political and social debate regarding issues of identity in our postmodern ...society. In the dominant interpretations of this pivotal Hegelian concept--for example in Honneth's or Fukuyama's work--the relationship between self-consciousness and absolute "negativity" has not been given due consideration. Departing from Hegel's determination of sickness and death in his philosophy of nature, the specific role and nature of absolute negativity in his concept of spirit andfreedom will be clarified. Following the death of the immediate living being--as the manifestation of infinity in a finite entity--the free spirit is born. According to Hegel, man as a self-conscious being is not only part of infinite life, but he is this infinity in andfor itself. Recognition as the concept of spirit is the actualisation of self-consciousness through doubling itself: the I that becomes We and the We that becomes I. The infinity of the spirit that is actualised in and through a doubling of self-consciousness contains this death of its natural being--absolute negativity. Now, this recognition can only become "real" due to a reciprocal action of at least two self-conscious people: both acting against themselves and towards each other. As became clear in the battle of life and death, in which both parties put their lives at stake in trying to kill each other, this action against themselves--as the actualisation of absolute negativity--is only made possible by both parties acting against each other, thereby enabling each other to put their lives at risk. As long as both parties fight no recognition is actualised. For actual recognition both the negation of immediate nature and "education" (formation/Bildung) are necessary. Recognition in this sense implies that you "mean" something in the eyes of others on the basis of what you can do, your skills and attitudes. Now, in his philosophy of spirit for Hegel this formation offreedom (as the prerequisite of recognition) is actualised by labour, as the latter is professionally performed in the ethical life of a community (that is directed towards such actualisation of freedom). The so called system of needs, as presented in Hegel's reinterpretation of modern economy, is a vital moment for this actualisation of freedom in "civil society" (Burgerliche Gesellschaft). From the perspective of Hegel's concept of recognition and freedom, pressing issues concerning "identity" in postmodern society can be viewed and interpreted in a new way. The ubiquity of our technological consumer society tends to undermine socially fixed structures of recognition, erode communities and can therefore, lead to both alienation and mass formation. In an atomised and consumptive environment a compensative desire for recognition might manifest itself and remain inactive and turn into a cult of victimhood. This passive way of identity creation carries with it the risk offorming one's identity in an externally negative way, i.e. in an irresolvable battle against the supposed offenders. Such a counterculture might in fact destroy the elementary conditions for a civil society and give rise to a kind of postmodern "tribalisation". The article ends with a critical review of Hegel's concept of recognition from a wider perspective, looking at a more fundamental motive behind the primacy of selfconsciousness in modern philosophy. Could it be a manifestation of a titanic power in modernity? One that Hegel is trying to tame, but simultaneously falls prey to? This idea might also present us with an alternative perspective on both Hegel's philosophy of spirit and our current situation. KEYWORDS: recognition, freedom, nature, self-consciousness, negativity, education, labour, civil society, identity politics, consumer-culture TREFWOORDEN: erkenning, vrijheid, natuur, zelfbewustzijn, negativiteit, vorming, arbeid, burgermaatschappij, identiteitspolitiek, consumptiecultuur
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