Current agricultural practices, developed during the green revolution, are becoming unsustainable, especially in the face of climate change and growing populations. Nanotechnology will be an ...important driver for the impending agri-tech revolution that promises a more sustainable, efficient and resilient agricultural system, while promoting food security. Here, we present the most promising new opportunities and approaches for the application of nanotechnology to improve the use efficiency of necessary inputs (light, water, soil) for crop agriculture, and for better managing biotic and abiotic stress. Potential development and implementation barriers are discussed, emphasizing the need for a systems approach to designing proposed nanotechnologies.
The need for appropriate science and regulation to underpin nanosafety is greater than ever as ongoing advances in nanotechnology are rapidly translated into new industrial applications and ...nano-enabled commercial products. Nevertheless, a disconnect persists between those examining risks to human and environmental health from nanomaterials. This disconnect is not atypical in research and risk assessment and has been perpetuated in the case of engineered nanomaterials by the relatively limited overlap in human and environmental exposure pathways. The advent of agri-nanotechnologies brings both increased need and opportunity to change this status quo as it introduces significant issues of intersectionality that cannot adequately be addressed by current discipline-specific approaches alone. Here, focusing on the specific case of nanoparticles, we propose that a transdisciplinary approach, underpinned by the One Health concept, is needed to support the sustainable development of these technologies.
Various nano-enabled strategies are proposed to improve crop production and meet the growing global demands for food, feed and fuel while practising sustainable agriculture. After providing a brief ...overview of the challenges faced in the sector of crop nutrition and protection, this Review presents the possible applications of nanotechnology in this area. We also consider performance data from patents and unpublished sources so as to define the scope of what can be realistically achieved. In addition to being an industry with a narrow profit margin, agricultural businesses have inherent constraints that must be carefully considered and that include existing (or future) regulations, as well as public perception and acceptance. Directions are also identified to guide future research and establish objectives that promote the responsible and sustainable development of nanotechnology in the agri-business sector.
Ultrasensitive Multifunctional Electronic SkinIn article number 2304004, Junshan Liu and co‐workers present an environment‐adaptable and ultrasensitive multifunctional e‐skin by using ...crack‐localization strategy. Cracked part and non‐cracked serpentine part are used for sensing strain and temperature, respectively. The e‐skin can be used in harsh environments, therefore it is of great potential for both human and robot‐oriented applications.
Fast, cheap, and reliable DNA sequencing could be one of the most disruptive innovations of this decade, as it will pave the way for personalized medicine. In pursuit of such technology, a variety of ...nanotechnology-based approaches have been explored and established, including sequencing with nanopores. Owing to its unique structure and properties, graphene provides interesting opportunities for the development of a new sequencing technology. In recent years, a wide range of creative ideas for graphene sequencers have been theoretically proposed and the first experimental demonstrations have begun to appear. Here, we review the different approaches to using graphene nanodevices for DNA sequencing, which involve DNA passing through graphene nanopores, nanogaps, and nanoribbons, and the physisorption of DNA on graphene nanostructures. We discuss the advantages and problems of each of these key techniques, and provide a perspective on the use of graphene in future DNA sequencing technology.
RNA origami is a method for designing RNA nanostructures that can self-assemble through co-transcriptional folding with applications in nanomedicine and synthetic biology. However, to advance the ...method further, an improved understanding of RNA structural properties and folding principles is required. Here we use cryogenic electron microscopy to study RNA origami sheets and bundles at sub-nanometre resolution revealing structural parameters of kissing-loop and crossover motifs, which are used to improve designs. In RNA bundle designs, we discover a kinetic folding trap that forms during folding and is only released after 10 h. Exploration of the conformational landscape of several RNA designs reveal the flexibility of helices and structural motifs. Finally, sheets and bundles are combined to construct a multidomain satellite shape, which is characterized by individual-particle cryo-electron tomography to reveal the domain flexibility. Together, the study provides a structural basis for future improvements to the design cycle of genetically encoded RNA nanodevices.
Triboelectrification is an effect that is known to each and every one probably since ancient Greek time, but it is usually taken as a negative effect and is avoided in many technologies. We have ...recently invented a triboelectric nanogenerator (TENG) that is used to convert mechanical energy into electricity by a conjunction of triboelectrification and electrostatic induction. As for this power generation unit, in the inner circuit, a potential is created by the triboelectric effect due to the charge transfer between two thin organic/inorganic films that exhibit opposite tribo-polarity; in the outer circuit, electrons are driven to flow between two electrodes attached on the back sides of the films in order to balance the potential. Since the most useful materials for TENG are organic, it is also named organic nanogenerator, which is the first using organic materials for harvesting mechanical energy. In this paper, we review the fundamentals of the TENG in the three basic operation modes: vertical contact-separation mode, in-plane sliding mode, and single-electrode mode. Ever since the first report of the TENG in January 2012, the output power density of TENG has been improved 5 orders of magnitude within 12 months. The area power density reaches 313 W/m2, volume density reaches 490 kW/m3, and a conversion efficiency of ∼60% has been demonstrated. The TENG can be applied to harvest all kinds of mechanical energy that is available but wasted in our daily life, such as human motion, walking, vibration, mechanical triggering, rotating tire, wind, flowing water, and more. Alternatively, TENG can also be used as a self-powered sensor for actively detecting the static and dynamic processes arising from mechanical agitation using the voltage and current output signals of the TENG, respectively, with potential applications for touch pad and smart skin technologies. To enhance the performance of the TENG, besides the vast choices of materials in the triboelectric series, from polymer to metal and to fabric, the morphologies of their surfaces can be modified by physical techniques with the creation of pyramid-, square-, or hemisphere-based micro- or nanopatterns, which are effective for enhancing the contact area and possibly the triboelectrification. The surfaces of the materials can be functionalized chemically using various molecules, nanotubes, nanowires, or nanoparticles, in order to enhance the triboelectric effect. The contact materials can be composites, such as embedding nanoparticles in a polymer matrix, which may change not only the surface electrification but also the permittivity of the materials so that they can be effective for electrostatic induction. Therefore, there are numerous ways to enhance the performance of the TENG from the materials point of view. This gives an excellent opportunity for chemists and materials scientists to do extensive study both in the basic science and in practical applications. We anticipate that a better enhancement of the output power density will be achieved in the next few years. The TENG is possible not only for self-powered portable electronics but also as a new energy technology with potential to contribute to the world energy in the near future.
Wearable systems that monitor muscle activity, store data and deliver feedback therapy are the next frontier in personalized medicine and healthcare. However, technical challenges, such as the ...fabrication of high-performance, energy-efficient sensors and memory modules that are in intimate mechanical contact with soft tissues, in conjunction with controlled delivery of therapeutic agents, limit the wide-scale adoption of such systems. Here, we describe materials, mechanics and designs for multifunctional, wearable-on-the-skin systems that address these challenges via monolithic integration of nanomembranes fabricated with a top-down approach, nanoparticles assembled by bottom-up methods, and stretchable electronics on a tissue-like polymeric substrate. Representative examples of such systems include physiological sensors, non-volatile memory and drug-release actuators. Quantitative analyses of the electronics, mechanics, heat-transfer and drug-diffusion characteristics validate the operation of individual components, thereby enabling system-level multifunctionalities.