Correction for 'Benzoflavone derivatives as potent antihyperuricemic agents' by Jatinder V. Singh
et al.
,
MedChemCommun
, 2019, DOI:
10.1039/c8md00512e
.
Herein, we demonstrate that tritylamines undergo an unprecedented copper-mediated cyclization involving the cleavages of two CH bonds and one CN bond to give 9-arylacridine derivatives. This kind ...of acridines is of interest due to their biological properties and their unique optical and electro- and photochemical properties. Some of obtained acridine derivatives exhibit intense fluorescence in the solid state.
SNH Arylamination of 5-, 6-, 7-, and 8-nitroquinolines in anhydrous DMSO gave not only the arylamino derivatives of the respective nitroquinolines, but also the arylamino derivatives of ...nitrosoquinolines. In the case of 6-nitroquinoline, the first representatives of polycyclic structures on the basis of pyrido3,2-aphenazine 7-oxide were isolated.
A diastereoselective zinc-mediated propargylation of non-enolizable norbornyl alpha-diketones and an efficient AgI-catalyzed cycloisomerization of the resulting alpha-keto homopropargyl alcohols ...with terminal alkynes leading to spirocyclic dihydrofurans have been reported. The dihydrofurans obtained were subjected to hydrogenation to afford spiro tetrahydrofuran derivatives in nearly quantitative yields (98-99%). Eventually, the prepared alpha-spiro tetrahydrofuran norbornyl monoketones were utilized as precursors for acid-mediated Grob-type fragmentation reactions and converted into 1-oxaspiro4.5decan-6-one derivatives by treatment with p-toluenesulfonic acid.
Codes of finance Lepinay, Vincent Antonin
2011., 20110808, 2011, 2011-08-08, 20110101, 2011-08
eBook, Book
The financial industry's invention of complex products such as credit default swaps and other derivatives has been widely blamed for triggering the global financial crisis of 2008. Codes of Finance ...takes readers behind the scenes of the equity derivatives business at one of the world's leading investment banks before the crisis, providing a detailed firsthand account of the creation, marketing, selling, accounting, and management of these financial instruments--and of how they ultimately created havoc inside and outside the bank.
An efficient synthesis of N-substituted indole derivatives was realized by combining the Pd-catalyzed one-pot multicomponent coupling approach with cleavage of the C(sp3)N bonds. Three or four ...components of aryl iodides, alkynes, and amines were involved in this coupling process. The cyclopentadiene-phosphine ligand showed high efficiency. A variety of aryl iodides, including cyclic and acyclic tertiary amino aryl iodides, and substituted 1-bromo-2-iodobenzene derivatives could be used. Both symmetric and unsymmetric alkynes substituted with alkyl, aryl, or trimethylsilyl groups could be applied. Cyclic secondary amines such as piperidine, morpholine, 4-methylpiperidine, 1-methylpiperazine, 2-methylpiperidine, and acyclic amines including secondary and primary amines all showed good reactivity. Further application of the resulting indole derivatives was demonstrated by the synthesis of benzosilolo2,3-bindole. PUBLICATION ABSTRACT
•The fractional differences and sums within delta and nabla are studied summarized and related by some identities so that it becomes helpful to proceed to other types of fractional differences.•The ...definition of left and right fractional differences with discrete exponential kernels and their corresponding sums have been given and studied on the time scale hZ. (CFC and CFR h-fractional differences and their corresponding CF h-fractional sums)•The definition of left and right fractional differences with discrete MittagLeffler kernels and their corresponding sums have been given and studied on the time scale hZ. (ABC and ABR h-fractional differences and their corresponding AB h-fractional sums)•Working on hZ will guarantee better numerical solutions for complex system models depending on discrete fractional calculus and it will affect the domain of convergence for the fractional differences and sums.
The aim of this article is to recall and study fractional derivatives with singular kernels on hZ and define fractional derivatives with non-singular exponential and Mittag–Leffler kernels on hZ and study some of their properties. We shall follow the nabla time scale analysis and relate the h−nabla classical discrete fractional derivatives to the delta existing ones studied before by some authors. Some dual identities between left and right and delta and nabla, left and right h−fractional difference types will be investigated. The nabla h− discrete versions of the Mittag-Leffler functions will be recalled by means of the nabla h−fatorial functions and nabla h−Taylor polynomials. The discrete Laplace on hZ and its convolution theory are used often to proceed in our investigation. The obtained results will generalize the nabla classical discrete fractional differences and the nabla discrete fractional differences with discrete exponential and ML−kernels studied recently by Abdeljawad and Baleanu by setting h=1.
A novel, efficient, and practical method for the synthesis of imidazopyridine derivatives has been developed through the copper-catalyzed aerobic oxidative CH functionalization of substituted ...pyridines with N-(alkylidene)-4H-1,2,4-triazol-4-amines. The procedure occurs by cleavage of the NN bond in the N-(alkylidene)-4H-1,2,4-triazol-4-amines and activation of an aryl CH bond in the substituted pyridines. This is the first example of the preparation of imidazopyridine derivatives by using pyridines as the substrates by transition-metal-catalyzed CH functionalization. This method should provide a novel and efficient strategy for the synthesis of other nitrogen heterocycles. PUBLICATION ABSTRACT
No nonlocality. No fractional derivative Tarasov, Vasily E.
Communications in nonlinear science & numerical simulation,
September 2018, 2018-09-00, 20180901, Letnik:
62
Journal Article
Recenzirano
Odprti dostop
•Principle of nonlocality for fractional derivatives is suggested.•A criterion, which allows one to identify false fractional derivatives, is proposed.•Conformable and local fractional derivatives ...are equivalent to integer derivatives.•Alternative and M-fractional derivatives are equivalent to integer derivatives.•The Caputo–Fabrizio fractional derivatives are equivalent to integer derivatives.
The paper discusses the characteristic properties of fractional derivatives of non-integer order. It is known that derivatives of integer orders are determined by properties of differentiable functions only in an infinitely small neighborhood of the considered point. Therefore differential equation, which is considered for this point and contains a finite number of integer-order derivatives, cannot describe nonlocality in space and time. This allows us to propose a principle of nonlocality for fractional derivatives. We state that if the differential equation with fractional derivative can be presented as a differential equation with a finite number of integer-order derivatives, then this fractional derivative cannot be considered as a derivative of non-integer order. This means that all results obtained for this type of fractional derivatives can be derived by using differential operators with integer orders. To illustrate the application of the nonlocality principle, we prove that the conformable fractional derivative, the M-fractional derivative, the alternative fractional derivative, the local fractional derivative and the Caputo–Fabrizio fractional derivatives with exponential kernels cannot be considered as fractional derivatives of non-integer orders.
Aberrant fetal programming in gestational diabetes mellitus seems to increase the risk of obesity, type 2 diabetes, and cardiovascular disease. The inability to accurately identify gestational ...diabetes mellitus in the first trimester of pregnancy has thwarted ascertaining whether early therapeutic interventions reduce the predisposition to these prevalent medical disorders.
A metabolomics study was conducted to determine whether advanced analytical methods could identify accurate predictors of gestational diabetes mellitus in early pregnancy.
This nested observational case-control study was composed of 92 gravidas (46 in the gestational diabetes mellitus group and 46 in the control group) in early pregnancy, who were matched by maternal age, body mass index, and gestational age at urine collection. Gestational diabetes mellitus was diagnosed according to community standards. A comprehensive metabolomics platform measured 626 endogenous metabolites in randomly collected urine. Consensus multivariate criteria or the most important by 1 method identified low–molecular weight metabolites independently associated with gestational diabetes mellitus, and a classification tree selected a subset most predictive of gestational diabetes mellitus.
Urine for both groups was collected at a mean gestational age of 12 weeks (range, 6–19 weeks’ gestation). Consensus multivariate analysis identified 11 metabolites independently linked to gestational diabetes mellitus. Classification tree analysis selected a 7-metabolite subset that predicted gestational diabetes mellitus with an accuracy of 96.7%, independent of maternal age, body mass index, and time of urine collection.
Validation of this high-accuracy model by a larger study is now needed to support future studies to determine whether therapeutic interventions in the first trimester of pregnancy for gestational diabetes mellitus reduce short- and long-term morbidity.
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