Maščobno tkivo ima vlogo pri številnih endokrinih in presnovnih procesih. Lepin je bil med prvimi odkritimi dejavniki iz maščobnega tkiva, ki delujejo avto-, para- in endokrino. Od opredelitve ...leptina so odkrili še številne druge dejavnike, od katerih se nekateri izločajo iz maščobnih celic, nekateri pa iz drugih celic maščobnega tkiva.
Adipose tissue is implicated in many endocrine and metabolic processes. Leptin was among the first identified adipose-secreted factors, which act in an auto-, para- and endocrine manner. Since ...leptin, many other adipose tissue factors were determined, some primarily secreted from the adipocytes, some from other cells of the adipose tissue.
So-called adipokines are not only involved in obesity and its complications, as are insulin resistance, type 2 diabetes and other components of the metabolic syndrome, but also in growth, reproduction, bone metabolism, immune response, cancer development and many other important biological processes. Research in the field of adipokines has revealed new insights into the physiological and pathophysiologal processes and opened new therapeutic possibilities. In the present article, a special emphasis is devoted to research in children and adolescents.
Maščobno tkivo ima vlogo pri številnih endokrinih in presnovnih procesih. Lepin je bil med prvimi odkritimi dejavniki iz maščobnega tkiva, ki delujejo avto-, para- in endokrino. Od opredelitve leptina so odkrili še številne druge dejavnike, od katerih se nekateri izločajo iz maščobnih celic, nekateri pa iz drugih celic maščobnega tkiva.
Tako imenovani adipokini niso povezani le z debelostjo in njenimi zapleti, kot so rezistenca proti inzulinu, sladkorna bolezen tipa 2 in druge komponente metabolnega sindroma, temveč tudi z rastjo, razmnoževanjem, presnovo kosti, imunskim odzivom, razvojem rakavih bolezni in mnogimi drugimi pomembnimi biološkimi procesi. Raziskave na področju adipokinov so opredelile nove fiziološke in patofiziološke procese in odprle nove možnosti zdravljenja. V tem prispevku poseben poudarek namenjamo raziskavam pri otrocih in mladostnikih.
Hiperandrogenemija u postmenopauzi prezentira se simptomima virilizacije. Navedeno stanje zahtijeva pomnu dijagnostičku obradu radi pronalaženja uzroka povišenih vrijednosti androgenih hormona te ...planiranja ade- kvatnog liječenja. Diferencijalno dijagnostički između ostalog u obzir dolaze tumori nadbubrežnih žijezda i jajnika.
Grigoris Lambrakis bio je grčki političar, liječnik, sportaš i član Medicinskog fakulteta Sveučilišta u Ateni. Kao sportaš, Lambrakis je držao grčki rekord u skoku u dalj tijekom dvadeset i tri ...godine, a osvojio je i nekoliko zlatnih medalja na Balkanskim atletskim igrama. Imao je izvrsno medicinsko obrazovanje. Kao predavač na Atenskom sveučilištu, Lambrakis je postao pionirom ginekološke endokrinologije. U njegovoj se liječničkoj karijeri očitovala njegova dobrohotnost. Također, neprestano je prisustvovao međunarodnim pacifističkim susretima i prosvjedima. Njegova je politička karijera zasjenila njegov medicinski rad i sveučilišni rad predavača opstetricije i ginekologije. Lambrakis je svjetski poznat kao mučenik za mir. Cilj je ovog izlaganja predstaviti njegov život, a posebice pojasniti njegova medicinska postignuća.
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Provider: - Institution: - Data provided by Europeana Collections- All metadata published by Europeana are available free of restriction under the Creative Commons CC0 1.0 Universal Public Domain ...Dedication. However, Europeana requests that you actively acknowledge and give attribution to all metadata sources including Europeana
Provider: - Institution: - Data provided by Europeana Collections- All metadata published by Europeana are available free of restriction under the Creative Commons CC0 1.0 Universal Public Domain ...Dedication. However, Europeana requests that you actively acknowledge and give attribution to all metadata sources including Europeana
Provider: - Institution: - Data provided by Europeana Collections- All metadata published by Europeana are available free of restriction under the Creative Commons CC0 1.0 Universal Public Domain ...Dedication. However, Europeana requests that you actively acknowledge and give attribution to all metadata sources including Europeana
Provider: - Institution: - Data provided by Europeana Collections- All metadata published by Europeana are available free of restriction under the Creative Commons CC0 1.0 Universal Public Domain ...Dedication. However, Europeana requests that you actively acknowledge and give attribution to all metadata sources including Europeana
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