Poslije dr. Kamila Firingera koji je udario temelje Državnom arhivu u Osijeku 1952. godine izredalo se nekoliko ravnatelja koji su s većim ili manjim uspjehom pomogli da Osječki arhiv postane glavni ...arhiv Slavonije i dominantno mjesto za povijesna istraživanja tog područja. Uloga dr. Stjepana Sršana, rođenog u međimurskom Podturnu 7. travnja 1941.. a umrlog u Osijeku 30. srpnja 2014. nije malo. On se je bavio različitim temama, a istraživanje povijesti plemstva u području gdje je ono imalo vodeću ulogu na političkom i gospodarsku planu svakako nije malo. Sršan je u tome načinio najznačajniji iskorak i time omogućio sadašnjim i budućim povjesničarima da laganije istraže pojedine elemente te povijesti.
Prague, 24 June: Another two cases of A/H1N1 (swine) flu have been registered in the Czech Republic, bringing the total to nine, Health Ministry spokesman Vlastimil Srsen told CTK today. "The eighth ...case is a young woman who returned to the Czech Republic from Canada on Wednesday, 17 June. On the day of arrival she registered first symptoms, mainly fatigue and feeling pressure in her chest," Srsen said.
Prague, 4 June: The Czech Republic has confirmed a second case of the new H1N1 (swine) flu, the infected person being a woman who has arrived from the US state of Arizona, Health Ministry spokesman ...Vlastimil Srsen told CTK today. "The national reference laboratory for influenza today confirmed the second case of the infection by the new A/H1N1 flu virus. A woman who arrived from Arizona on May 27 has been tested positive," Srsen said. "Before an anti-virus medicine was administered to her the doctors took samples for virological tests. The course of the disease was mild," Srsen said.
Rijeka, 5 February: British national Paul Dexter Farrow, indicted along with Ivan Andabak of Croatia for smuggling 660 kilograms of cocaine, has been extradited by Spain to Croatia, Rijeka County ...Court spokesman Zoran Srsen said on Monday. The Rijeka court requested Dexter Farrow's extradition from Gambia, where he was at the time, as well as his questioning and delivery of documents related to the case, but Gambia failed to do so, Srsen said.
Nonlinear optics is the study of the interaction of intense laser light with matter. This Third Edition has been rewritten to conform to the standard SI system of units and includes comprehensively ...updated material on the latest developments in the field. The book introduces the entire field of optical physics and specifically the area of nonlinear optics. It focuses on the fundamental issues including the electromagnetic origin of optical phenomena, the quantum mechanical description of the optical properties of matter, the role of spatial symmetries in determining the optical response, causality and Kramers Kronig relations, and ultrafast and high intensity optical effects.
Background:
While the role of stereotactic radiotherapy for brain metastases is increasing, evidence on the comparative efficacy and safety of fractionated stereotactic radiotherapy (FSRT) and ...single-session radiosurgery (SRS) is scarce.
Methods:
Longitudinal volumetric analysis was performed in a consecutive cohort of 120 patients and 190 brain metastases (>0.065 cm
3
in volume / > ~5 mm in diameter) treated exclusively with FSRT (
n
= 98) and SRS (
n
= 92), respectively. A total of 972 tumor segmentations was used, averaging 5.1 time points per metastasis. Progression was defined using a volumetric extension of the RANO-BM criteria. Local control and radionecrosis were compared for lesions treated with FSRT and SRS, respectively.
Results:
Metastases treated with FSRT were significantly larger at baseline (mean, 4.66 vs. 0.40 cm
3
,
p
< 0.001). Biologically effective dose (BED) for metastases (α/β = 12, linear-quadratic-cubic model) was significantly associated with local control, whereas BED for normal brain (α/β = 2, linear-quadratic model) was significantly associated with radionecrosis. Median time to local progression was 22.9 months in the FSRT group compared to 14.5 months in the SRS group (
p
= 0.022). Overall radionecrosis rate at 12 months was 3.4% for FSRT and 14.8% for SRS (
p
= 0.010). Radionecrosis °IV requiring resection with histologic proof of radiation necrosis also was significantly reduced in the FSRT group (FSRT 0.0% vs. SRS 3.9%,
p
= 0.041). In multivariate analysis, FSRT was associated with reduced risk of progression (HR 0.47,
p
= 0.015) and reduced risk of radionecrosis (HR 0.18,
p
= 0.045).
Conclusions:
This volumetric study provides initial evidence that the improvements in therapeutic ratio expected for FSRT in larger brain metastases, might equally extend into the domain of smaller metastases, traditionally less considered for fractionated treatment. FSRT might constitute an important tool to further increase local control and reduce radionecrosis risk in stereotactic radiotherapy for brain metastases, that should be assessed in randomized intervention trials.
Gender Affirmation J Salgado, Christopher; J. Monstrey, Stan; Djordjevic, Miroslav
2016, 20170101
eBook
Some people pursue medical interventions as part of the process of expressing their gender, and an increasing number of gender affirmation surgeries are being performed. This book, which provides ...comprehensive coverage of the subject, is edited by three well-respected and experienced authors with over 20 contributors from around the world. It features full coverage of both medical and surgical treatment, supported by over 350 full-color drawings and photos and surgical video.
PDF
