Based on the investigation of melt inclusions using electron and ion microprobe analysis, we estimated the composition, evolution, and formation conditions of magmas responsible for the ...calcite-bearing ijolites and carbonatites of the Belaya Zima alkaline carbonatite complex (eastern Sayan, Russia). Primary melt and coexisting crystalline inclusions were found in the nepheline and calcite of these rocks. Diopside, amphibole (?), perovskite, potassium feldspar, apatite, calcite, pyrrhotite, and titanomagnetite were identified among the crystalline inclusions. The melt inclusions in nepheline from the ijolites are completely crystallized. The crystalline daughter phases of these inclusions are diopside, phlogopite, apatite, calcite, magnetite, and cuspidine. During thermometric experiments with melt inclusions in nepheline, the complete homogenization of the inclusions was attained through the dissolution of a gas bubble at temperatures of 1120-1130°C. The chemical analysis of glasses from the homogenized melt inclusions in nepheline of the ijolites revealed significant variations in the content of components: from 36 to 48 wt % SiO^sub 2^, from 9 to 21 wt % Al^sub 2^O^sub 3^, from 8 to 25 wt % CaO, and from 0.6 to 7 wt % MgO. All the melts show very high contents of alkalis, especially sodium. According to the results of ion microprobe analysis, the average content of water in the melts is no higher than a few tenths of a percent. The most salient feature of the melt inclusions is the extremely high content of Nb and Zr. The glasses of melt inclusions are also enriched in Ta, Th, and light rare earth elements but depleted in Ti and Hf. Primary melt inclusions in calcite from the carbonatites contain a colorless glass and daughter phlogopite, garnet, and diopside. The silicate glass from the melt inclusions in calcite of the carbonatite is chemically similar to the glasses of homogenized melt inclusions in nepheline from the ijolites. An important feature of melt inclusions in calcite of the carbonatites is the presence in the glass of carbonate globules corresponding to calcite in composition. The investigation of melt inclusions in minerals of the ijolites and carbonatites and the analysis of the alkaline and ore-bearing rocks of the Belaya Zima Massif provided evidence for the contribution of crystallization differentiation and silicate-carbonate liquid immiscibility to the formation of these rocks. Using the obtained trace-element compositions of glasses of homogenized melt inclusions and various alkaline rocks and carbonatites, we determined to a first approximation the compositions of mantle sources responsible for the formation of the rock association of the Belaya Zima alkaline-carbonatite complex. The alkaline rocks and carbonatites were derived from the depleted mantle affected by extensive metasomatism. It is supposed that carbonate melts enriched in sodium and calcium were the main agents of mantle metasomatism.PUBLICATION ABSTRACT
We show that the KKM principle implies two new general fixed point theorems for the Kakutani maps or the Browder maps. Consequently, we give unified transparent proofs of many of well-known results.
We study the relations of almost lower semicontinuity, lower semicontinuity and other generalized lower semicontinuity; then we establish a new approximate selection theorem for almost lower ...semicontinuous multimaps with the generalized Zima type condition in
C
-spaces. Our result unify and extend the approximate selection theorems in many published works.
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Clinical trials have shown that combining beta-blockers and angiotensin-converting enzyme (ACE) inhibitors has an additive effect in reducing mortality in patients with left ventricular dysfunction ...following acute myocardial infarction. Whether this additive effect also occurs in unselected post-myocardial infarction patients is unknown.
In total, 5397 patients who were discharged from hospital after suffering an acute myocardial infarction were followed for 1 year. The primary endpoint was all-cause mortality. The effects of the medications on 1-year survival were analyzed using a Cox regression model, which included propensity scores for beta-blocker and ACE inhibitor use to take account of any potential imbalance in drug prescription rates.
At hospital discharge, 55.9% of patients were receiving beta-blockers and 45.1%, ACE inhibitors. The 1-year mortality rate was 5.5%. Overall, combination of the two medications significantly reduced the 1-year mortality rate (hazard ratio HR=0.51; 95% confidence interval IC, 0.32–0.82);
P<.005) to a greater extent than ACE inhibitors alone (HR=0.78; 95% CI, 0.54–1.12;
P=.2) or beta-blockers alone (HR=0.67; 95% CI, 0.43–1.05;
P=.08). The same trend was also observed in low-risk patients without acute heart failure who had an ejection fraction 40%.
In unselected post-myocardial infarction patients, combined prescription of beta-blockers and ACE inhibitors had an additive effect on the 1-year survival rate.
La combinación de bloqueadores beta e inhibidores de la enzima de conversión de la angiotensina (IECA) ha demostrado reducir la mortalidad en pacientes con infarto de miocardio y disfunción sistóli-ca. Sin embargo, no sabemos si esta asociación presenta efectos aditivos sobre la supervivencia al año en una po-blación no seleccionada de pacientes con infarto agudo de miocardio con y sin elevación del segmento ST.
Se realizó un seguimiento durante un año a 5.397 pacientes dados de alta tras un infarto agudo de miocardio. El criterio de valoración fue la mortalidad por cualquier causa. Para analizar el efecto de la medicación se utilizó el modelo de regresión logística de Cox, en el que se incluyó el
propensity score para compensar las posibles desviaciones en la prescripción de los 2 grupos de fármacos.
En el momento del alta, el 55,9% de los pacientes recibió bloqueadores betay el 45,1%, IECA. La mortalidad al año fue del 5,5%. En el grupo total, la combinación se asoció con una reducción significativa de la mortalidad (
hazard ratio HR = 0,51; intervalo de confian-za IC del 95%, 0,32–0,82); p < 0,005) superior a la de los IECA solos (HR = 0,78; IC del 95%, 0,54–1,12; p = 0,2) y los bloqueadores beta solos (HR = 0,67; IC del 95%, 0,43–1,05; p = 0,08). Esta misma tendencia se observó en los pacientes de bajo riesgo, sin insuficiencia cardiaca en fase aguda y con fracción de eyección ± 40%.
En una población no seleccionada de pacientes con infarto agudo de miocardio, la prescripción conjunta de bloquedores beta e IECA en el momento del alta hospitalaria muestra efectos aditivos sobre la super-vivencia al año.
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Żołnierze powstrzymują atak zimy, odśnieżają ulice.- Extended description:- Information:- Soldiers ...prevent attack of winter, they remove snow from the streets.- All metadata published by Europeana are available free of restriction under the Creative Commons CC0 1.0 Universal Public Domain Dedication. However, Europeana requests that you actively acknowledge and give attribution to all metadata sources including Europeana
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