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  • Comparison of serum S100B protein changes in off pump vs on pump CABG
    Trunk, Primož ...
    ObjectiveČ The S100B protein has been recognized as an early marker of cerebral damage. Elevated levels of S100B were detected in patients after the cardiac surgery with the use of cardiopulmonary ... bypass. We were interested if there are any differences in S100B serum concentrations between the off pump CABG and on pump CABG group of patients. MethodsČ We studied 35 patients undergoing CABG surgery and measured the concentration of S100B protein in blood samples taken preoperatively, at the end of operation and first day after the surgery. The patients were divided in two groups, those having off-pump operations and those having heart operations with the use of cardiopulmonary bypass. ResultsČ We found peak levels of S100B immediately after surgery. The median concentration of S100B in off pump group was 0.40 gžL compared to 1.50 gžL in on-pump group of patients (p=0.0006). ConclusionsČ The results are consistent with some other studies and suggest that heart surgery without the use of cardiopulmonary bypass could be less invasive regarding the cerebral damage.
    Vir: 5th International Congress on Coronary Artery Disease - From Prevention to Intervention - ICCAD, Florence, Italy, October 19-22, 2003 : abstracts (str. 142)
    Vrsta gradiva - prispevek na konferenci
    Leto - 2003
    Jezik - angleški
    COBISS.SI-ID - 1434225

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