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  • Kawaguchi, Shuji; Matsuda, Fumihiko

    Methods in molecular biology (Clifton, N.J.), 01/2020, Letnik: 2131
    Journal Article

    HLA is essential for various medical applications, such as genomic studies of multifactorial diseases, including immune system and inflammation-related disorders. Therefore, an accurate HLA typing method that is applicable for any allele registered in HLA allele databases is required to deduce scientific evidence related to disorders. Here, we describe a method for determining HLA alleles from next-generation sequencing (NGS) results by using currently available HLA sequence data in public HLA databases and show its application in association analysis.