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  • Roellinghoff, F; Benilov, A; Dauvergne, D; Dedes, G; Freud, N; Janssens, G; Krimmer, J; Létang, J M; Pinto, M; Prieels, D; Ray, C; Smeets, J; Stichelbaut, F; Testa, E

    Physics in medicine & biology, 03/2014, Letnik: 59, Številka: 5
    Journal Article

    Prompt-gamma profile was measured at WPE-Essen using 160 MeV protons impinging a movable PMMA target. A single collimated detector was used with time-of-flight (TOF) to reduce the background due to neutrons. The target entrance rise and the Bragg peak falloff retrieval precision was determined as a function of incident proton number by a fitting procedure using independent data sets. Assuming improved sensitivity of this camera design by using a greater number of detectors, retrieval precisions of 1 to 2 mm (rms) are expected for a clinical pencil beam. TOF improves the contrast-to-noise ratio and the performance of the method significantly.