E-viri
Recenzirano
Odprti dostop
-
Weaver, Richard J; Blomme, Eric A; Chadwick, Amy E; Copple, Ian M; Gerets, Helga H J; Goldring, Christopher E; Guillouzo, Andre; Hewitt, Philip G; Ingelman-Sundberg, Magnus; Jensen, Klaus Gjervig; Juhila, Satu; Klingmüller, Ursula; Labbe, Gilles; Liguori, Michael J; Lovatt, Cerys A; Morgan, Paul; Naisbitt, Dean J; Pieters, Raymond H H; Snoeys, Jan; van de Water, Bob; Williams, Dominic P; Park, B Kevin
Nature reviews. Drug discovery, 02/2020, Letnik: 19, Številka: 2Journal Article
Drug-induced liver injury (DILI) is a patient-specific, temporal, multifactorial pathophysiological process that cannot yet be recapitulated in a single in vitro model. Current preclinical testing regimes for the detection of human DILI thus remain inadequate. A systematic and concerted research effort is required to address the deficiencies in current models and to present a defined approach towards the development of new or adapted model systems for DILI prediction. This Perspective defines the current status of available models and the mechanistic understanding of DILI, and proposes our vision of a roadmap for the development of predictive preclinical models of human DILI.
Avtor
![loading ... loading ...](themes/default/img/ajax-loading.gif)
Vnos na polico
Trajna povezava
- URL:
Faktor vpliva
Dostop do baze podatkov JCR je dovoljen samo uporabnikom iz Slovenije. Vaš trenutni IP-naslov ni na seznamu dovoljenih za dostop, zato je potrebna avtentikacija z ustreznim računom AAI.
Leto | Faktor vpliva | Izdaja | Kategorija | Razvrstitev | ||||
---|---|---|---|---|---|---|---|---|
JCR | SNIP | JCR | SNIP | JCR | SNIP | JCR | SNIP |
Baze podatkov, v katerih je revija indeksirana
Ime baze podatkov | Področje | Leto |
---|
Povezave do osebnih bibliografij avtorjev | Povezave do podatkov o raziskovalcih v sistemu SICRIS |
---|
Vir: Osebne bibliografije
in: SICRIS
To gradivo vam je dostopno v celotnem besedilu. Če kljub temu želite naročiti gradivo, kliknite gumb Nadaljuj.