Calibration of the Advanced LIGO detectors is the quantification of the detectors' response to gravitational waves. Gravitational waves incident on the detectors cause phase shifts in the interferometer laser light which are read out as intensity fluctuations at the detector output. Understanding this detector response to gravitational waves is crucial to producing accurate and precise gravitational wave strain data. Estimates of binary black hole and neutron star parameters and tests of general relativity require well-calibrated data, as miscalibrations will lead to biased results. We describe the method of producing calibration uncertainty estimates for both LIGO detectors in the first and second observing runs.