E-viri
Recenzirano
-
Vecchi, V; Maccolini, E; Oddo Bravetti, G; Guidelli Guidi, S; Serra, L
Tumori, 1984-Dec-31, Letnik: 70, Številka: 6Journal Article
The authors describe a case of optic neuropathy in a child undergoing MOPP chemotherapy for Hodgkin's disease stage IIISA. Visual acuity improved after substitution of the aforementioned regimen with ABVD chemotherapy, and reached 1 during maintenance therapy with vinblastine. Various neurologic deficits have been ascribed to vincristine, a well-known neurotoxin. This case of optic neuropathy is supposed to be a rare example of involvement of the 2nd cranial nerve due to vinca alkaloids. The absence of neurotoxicity of vinblastine in this case is emphasized.
