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  • DNA sequencing at 40: past,...
    Shendure, Jay; Balasubramanian, Shankar; Church, George M; Gilbert, Walter; Rogers, Jane; Schloss, Jeffery A; Waterston, Robert H

    Nature (London), 10/2017, Letnik: 550, Številka: 7676
    Journal Article

    This review commemorates the 40th anniversary of DNA sequencing, a period in which we have already witnessed multiple technological revolutions and a growth in scale from a few kilobases to the first human genome, and now to millions of human and a myriad of other genomes. DNA sequencing has been extensively and creatively repurposed, including as a 'counter' for a vast range of molecular phenomena. We predict that in the long view of history, the impact of DNA sequencing will be on a par with that of the microscope.