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  • Drop-out, adherence, and co...
    Motl, Robert W; Russell, Daniel I; Pilutti, Lara A; Metse, Alexandra P; Marck, Claudia H; Chan, Bryan; Zheng, Peixuan; Learmonth, Yvonne C

    Multiple sclerosis, 04/2024, Letnik: 30, Številka: 4-5
    Journal Article

    We documented reporting and rates of drop-out, adherence, and compliance from 40 randomized controlled trials (RCTs) included in our meta-analysis on safety of exercise training (ET) in MS. We adopted definitions and metrics of adherence and compliance provided by the MoXFo adherence group. Drop-out was reported in 100% of the RCTs and approximated 10% for intervention and control conditions. Adherence and compliance were reported in approximately 50% and 10% of the RCTs, respectively, and approximated 80% and 70%, respectively. Standardized metrics for reporting adherence and compliance are important in future RCTs for understanding the impact on outcomes and translation of research evidence into practice.